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Castor EDC vs OpenClinica Comparison (2026)

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Castor EDC logo

Castor EDC

OpenClinica logo

OpenClinica

Overview

The only GCP & 21 CFR compliant system that's affordable for every researcher and has all the features of expensive systems. Start now.

OpenClinica is a compliant, all-in-one clinical data management platform offering electronic data capture with collaborative drag and drop interface for designing studies, randomization and supply management, patient reported outcomes (ePRO & eCOA), plus reporting tools with chart visualizations

  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials
  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials

Video & Screenshots

Pricing

Starting from

Empty state illustration for "No pricing info"

No pricing info

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

Starting from

1000

Per month

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

User reviews

4.7

204

5

4

3

2

1

141

58

4

1

0

  • Value for money
  • Ease of use
  • Features
  • Customer support
90%
would recommend this app

4.6

37

5

4

3

2

1

28

7

1

0

1

  • Value for money
  • Ease of use
  • Features
  • Customer support
85%
would recommend this app

Pros

“The option to come back and add more answers to a multiple-choice question while still working on the form (this is not a change to an answer but merely an addition of data). If I complete a form and later modify the contents of more than one question, the messages should be specific to each change rather than general for the entire page, since the reasons for each change might be different.”
DP

David P.

Research technician

“I’ve been working with several EDC instruments and in Castor I’ve found an all in one tool with randomization, monitoring, high security level data storing, and a great flexibility to customize the eCRF.”
JM

Javier M.

MD

“In particular the survey was well designed to perform real-time quality assessment to promote completion of each section and provide feedback if answers were unclear. If there are any problems, human staff were readily available to resolve them.”
WM

WILLIAM M.

Practicing physician. Director of clinical cancer research

Pros

“Our research on the efficacy and safety of medications was supported by OpenClinica's reporting and analytics capabilities, which gave us insights into patient demographics, treatment outcomes, and adverse events.”
AB

Angelica B.

University Intern

“The support provided by the Openclinica team cannot be beat. If I may list two things, the OC system is incredibly user friendly.”
Verified reviewer profile picture

Adam P.

Data Manager

“Some training sessions go really well, especially when you are with someone hire up on the support team, but there have been many sessions where the trainer is referring to a manual to instruct me on my question and I lose a lot of my "training hours" waiting for them to figure it out and then pass on the information.”
BF

Bethany F.

CDM II

Cons

“Also, I use an Ipad to log in to castor most of the times and I am not sure that when I need to input numbers on multiple fields the keyboard doesn't stay in numbers and I have to constantly swap from letters to numbers.”
EP

Evita P.

Senior Research Nurse

“Sometimes the automatic track changes is a bit too sensitive: when I'm filling in the questionnaire and make 1 mistake, I have to change everything and explain it for every changed field.”
LR

Lauren R.

Physician PhD-student

“The font size is too small.”
MI

Mona I.

Research Analyst

Cons

“The randomization tool is pretty sophisticated but it also costs extra and whenever you need to do updates to the tool it's a much more difficult process then simply publishing it to test.”
BF

Bethany F.

CDM II

“This also adds layers of difficulty to the testing.”
BF

Bethany F.

CDM II

  • Vendor responds to reviews
  • Last review2 years ago
  • Vendor responds to reviews
  • Last review3 years ago

Key features

  • Total features56
  • 21 CFR Part 11 Compliance
  • API
  • Access Controls/Permissions
  • Activity Dashboard
  • Alerts/Notifications
  • Audit Management
  • Audit Trail
  • CRF Tracking
  • Clinical Study Management
  • Configurable Workflow
  • Customizable Branding
  • Customizable Fields
  • Customizable Forms
  • Customizable Reports
  • Customizable Templates
  • Data Capture and Transfer
  • Data Extraction
  • Data Import/Export
  • Data Storage Management
  • Data Synchronization
  • Data Verification
  • Data Visualization
  • Digital Signature
  • Distributed Capture
  • Document Classification
  • Document Imaging
  • Document Management
  • Document Storage
  • Double Data Entry
  • Drag & Drop
  • EMR/EHR
  • Electronic Data Capture
  • Electronic Signature
  • Enrollments/Onboarding
  • Forms Management
  • HIPAA Compliant
  • Inventory Management
  • Metadata Management
  • Mobile Access
  • Monitoring
  • Multi-Language
  • Patient Management
  • Patient Monitoring
  • Progress Tracking
  • Randomization
  • Real-Time Data
  • Real-Time Monitoring
  • Real-Time Reporting
  • Reminders
  • Remote Data Capture
  • Reporting & Statistics
  • Reporting/Analytics
  • Role-Based Permissions
  • Scheduling
  • Secure Data Storage
  • Surveys & Feedback
  • Third-Party Integrations
  • Trial Design
  • User Management
  • Web Forms
  • Workflow Management
  • Total features35
  • 21 CFR Part 11 Compliance
  • API
  • Access Controls/Permissions
  • Activity Dashboard
  • Alerts/Notifications
  • Audit Management
  • Audit Trail
  • CRF Tracking
  • Clinical Study Management
  • Configurable Workflow
  • Customizable Branding
  • Customizable Fields
  • Customizable Forms
  • Customizable Reports
  • Customizable Templates
  • Data Capture and Transfer
  • Data Extraction
  • Data Import/Export
  • Data Storage Management
  • Data Synchronization
  • Data Verification
  • Data Visualization
  • Digital Signature
  • Distributed Capture
  • Document Classification
  • Document Imaging
  • Document Management
  • Document Storage
  • Double Data Entry
  • Drag & Drop
  • EMR/EHR
  • Electronic Data Capture
  • Electronic Signature
  • Enrollments/Onboarding
  • Forms Management
  • HIPAA Compliant
  • Inventory Management
  • Metadata Management
  • Mobile Access
  • Monitoring
  • Multi-Language
  • Patient Management
  • Patient Monitoring
  • Progress Tracking
  • Randomization
  • Real-Time Data
  • Real-Time Monitoring
  • Real-Time Reporting
  • Reminders
  • Remote Data Capture
  • Reporting & Statistics
  • Reporting/Analytics
  • Role-Based Permissions
  • Scheduling
  • Secure Data Storage
  • Surveys & Feedback
  • Third-Party Integrations
  • Trial Design
  • User Management
  • Web Forms
  • Workflow Management

Integrations

  • Total integrations1
  • eCRF
  • Total integrationsN/A
  • eCRF