Castor EDC vs Greenlight Guru Clinical

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Jotform

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The only GCP & 21 CFR compliant system that's affordable for every researcher and has all the features of expensive systems. Start now.

21 CFR Part 11 Compliance

Access Controls/Permissions

Activity Dashboard

Alerts/Notifications

Audit Management

Audit Trail

Clinical Study Management

Configurable Workflow

CRF Tracking

Customizable Branding

Customizable Fields

Customizable Forms

Customizable Reports

Customizable Templates

Data Capture and Transfer

Data Extraction

Data Import/Export

Data Storage Management

Data Synchronization

Data Verification

Data Visualization

Digital Signature

Distributed Capture

Document Classification

Document Imaging

Document Management

Document Storage

Drag & Drop

Electronic Data Capture

Electronic Signature

EMR/EHR

Enrollments/Onboarding

Forms Management

HIPAA Compliant

Metadata Management

Mobile Access

Monitoring

Multi-Language

Patient Management

Patient Monitoring

Progress Tracking

Randomization

Real-Time Data

Real-Time Monitoring

Real-Time Reporting

Reminders

Remote Data Capture

Reporting/Analytics

Role-Based Permissions

Secure Data Storage

Surveys & Feedback

Third-Party Integrations

Trial Design

User Management

Workflow Management

Castor EDC

Web-based

OpenClinica

Greenlight Guru Clinical

ClinCapture

Basic

Research technician

The option to come back and add more answers to a multiple-choice question while still working on the form (this is not a change to an answer but merely an addition of data). If I complete a form and later modify the contents of more than one question, the messages should be specific to each change rather than general for the entire page, since the reasons for each change might be different.

Senior Research Nurse

Also, I use an Ipad to log in to castor most of the times and I am not sure that when I need to input numbers on multiple fields the keyboard doesn't stay in numbers and I have to constantly swap from letters to numbers.

I’ve been working with several EDC instruments and in Castor I’ve found an all in one tool with randomization, monitoring, high security level data storing, and a great flexibility to customize the eCRF.

Practicing physician. Director of clinical cancer research

In particular the survey was well designed to perform real-time quality assessment to promote completion of each section and provide feedback if answers were unclear. If there are any problems, human staff were readily available to resolve them.

Clinical Research Practitioner

As mentioned, the randomisation aspect is quick, however since one of the updates the button has now moved to the left of the screen and it just says "not randomised". Until you select this option is may not be obvious that this is how you randomise patients as it looks like a statement, rather than an option to select.

Clinical research coordinator

Easy to navigate, less auto queries, less system checks inhibiting data entry, given ts a web application with no requirement to download the soft ware on a desk top, it’s easier to work on from anywhere and anytime.

Physician PhD-student

Sometimes the automatic track changes is a bit too sensitive: when I'm filling in the questionnaire and make 1 mistake, I have to change everything and explain it for every changed field.

It might be helpful to have a comment box available for each of the cases reported, in case the person completing the survey has any question about what is being asked for or is not certain that their best response is exactly what is being asked for.

Research Data Abstractor

once subject ID# has been made, it cannot be edited/corrected anymore like for example entering the subject number in a wrong format (for multicenter studies).

Data Officer

I like that I can see repeated forms and access monitoring section to see any outstanding queries.

More time to make changes or the ability to come back and modify them at any time while still filling out the form.

Sometimes it's seems like there are multiple places for the introduction text and the only way to find out was to just trail and error.

Medical staff

I can add complete studies and capture different types of data.

PhD Student

You can add and remove based on your Case Reporting Form or questionnaires

Study Coordinator

What I liked least about Castor was that it did not collect all the information that, in my personal opinion, was necessary for the complete management of the trial.

Veterinary Technician

Needs a location to see a comprehensive list of pets due for another sample collection or next year visit

in clinical trials, we use it to collect data from patients

Senior Research Nurse Study Coordinator

Even the ability to send surveys/questionnaires to patients is very convenient.

study coordinator

Combination of patient personal information in the same database as clinical information

Clinicial Project Manager

Sometimes, the queries are not visible in which CRFs are located.

Clinical Trial Pharmacist

Depending in which language you chose, it allows you to log in.

It was helpful that a good amount of time was allowed to enter multiple case reports.  

None so far maybe because this is the first trial we have on this EDC and not a lot of participants and not a lot of information to enter.

PhD-student and psychological assistent

Overall it's intuitive and if you have a technical question, you can e-mail and will get a quick response.

The flexibility to customize the EDC intrument.

The fields are very well categorised and it is easy to see where the information you need is located.

Clinical Data Manager

To find out a list of all Notification given to all staff.

Site couldnt enter different units for lab results

Nurse supervisor

Very good experience in handling forms and participant data.

Research Analyst

Data Entry

The way they showed the queries because it was difficult to respond.

I like how the EDC looks because it is very visual, and it is easy to see what remains to be completed.

consutant analyst

ease of access, ease of navigation, user friendly in allocating the stuy i needed for analyses and report

Pharmacist

The presentation of the website but it could be improved,

it is great so far. when I enter data it automatically saves.

Lead Clinical Research Coordinator

It was easy to navigate with no lag time or slowness to entering in data.

Clinical Research Coordinator

It is extremely useful and definitely simplifies data capture

This is a not very intuitive website but it has many functionalities.

Research Scientist MD, MPH

Queries are not salient enough and are sometimes easy to miss

Technical Supervisor

Visually I feel formatting could be better.

This type of structure makes my work easier

In addition, it is fast and without visual noise.

Clinical Reasearch

This is my first job in data entry and Castor has made it easy.

Castor EDC is a website easy to access but it could be improved

Research assistant

I rarely had issues with it and when I did, they were quickly/ easily resolved.

User Interface

Questionnaires

Ease of Use

Query Management

Layout

Among reviewers who comment on Castor EDC's layout, 88% feel positive. Users say the interface is visually clear, modern, and easy to navigate, supporting efficient data management. They appreciate the simplicity and flexibility. However, some reviewers mention clunky elements, excessive options, and inconsistent experience across devices.

Navigation

Clinical Trials

Bugs and Issues

Small Business

Mid-size Business

Large Enterprises

Freelancers

Castor

Viedoc

Viedoc delivers powerful eClinical solutions that streamline clinical trials, making data collection, management, and analysis faster and easier. Trusted in 75+ countries, powering 7,000+ studies with more than 1.6M+ participants.

Castor is the leading EDC platform, letting researchers build studies in hours and seamlessly integrate EMR/EHR, ePRO, eCOA, and device data. With 90% of studies passing UAT in under four weeks, Castor accelerates research with no-code setup, real-time monitoring, and full regulatory compliance.

Consultant Anaesthetist

Customer service and support has been fantastic throughout.

Clinical Research Associate

Greenlight Guru Clinical's electronic data capture is designed to help businesses in the medtech industry collect data from clinical investigations and post-market clinical follow-ups (PMCF). The platform offers predefined templates and QA files, which enable organizations to ensure compliance.

Approval Process Control

Web Forms

Proprietary

Senior Clinical Research Nurse - Team Leader

Very comprehensive feature set, including patient enrolment and real-time data collection, greatly enhances the efficiency of managing clinical trials.

Research Trial Manager

This created a lot of issues for us in the long run, as when you want to edit a single form at a certain timepoint, it ends up changing all the timepoints that use this same form

Clinical Research Facility team leader.

Its robust data collection and management features ensure high-quality data capture, significantly reducing errors.

Research Data Manager

We can raise only one query per question and if we want to edit the query, we have to close it first and open a new one.

Clinical Operations Associate

I dislike how only 1 eConsent module can be used per process, I would like the ability to have the signature in select spots for sub consent portions.

Senior Clinical Research Nurse

data entry information, especially when correcting/double checking for accuracy, can take time as users need to scroll up and down several times.

Research Nurse

Its comprehensive features ensure regulatory compliance and efficient data management, significantly enhancing our workflow.

Clinical Research Associate II

The lack of in-depth monitoring reports makes it difficult to generate detailed overview of data points.

Clinical Research Data Entry Clerk

You cannot navigate between visits without leaving page and entering participant view again.

i use Greenlight guru for multiple clinical trial studies and for the most part the system is sturdy, quick and easy to train others in.

limitation in tailoring the platform to the specific needs of the trial.

I like the overview of the data events per participant, show if rules, and the ease of use.

The platform is intuitive and easy to use, with a straightforward interface that simplifies the management of clinical trials.

It is a great tool for data gathering and the ease of use help researchers to lighten the load of their job.

Clinical Research Specialist

Additionally, it would be nice to have more filter options of the CRFs.

It saves significant time and brings accuracy to the study.

Clinical Trials Assistant

I found it difficult to find the add note's icon

The high cost of ownership is the only downside to be addressed.

Sr Manager of Clinical Affairs

We've worked around them but would like to see more updates and changes overtime.

it some have some hic-cups occasionally but its great for most trials and I would recommend it.

Overall I would say customer service support was very good and I was easily able to pull out important data.

It is easy to use for a small company that does not have a full data management team.

Easy to use for set up of studies and really quick and efficient system support team.

Castor EDC vs Greenlight Guru Clinical Comparison (2026)

Castor EDC

Greenlight Guru Clinical

Overview

Video & Screenshots

Pricing

User reviews

Key features

Integrations

Alternatives