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MailCleaner vs Microsoft Defender for Office 365 Comparison (2026)

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Good recommendations?

MailCleaner

Microsoft Defender for Office 365

Overview

MailCleaner offer cloud or on-premise anti spam and anti virus protection for ISP SME SMI & large companies, non profit organizations and governments

Microsoft Defender for Office 365 is a cloud-based email security software designed to help businesses automatically detect, investigate, and resolve potential email threats on a centralized platform. Supervisors can configure security policies, perform spoof checks, and maintain a record of reported incidents.

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Video & Screenshots

Pricing

Starting from

130

Per year

Free trial available
Credit cardless trial
Free account
Subscription based

Starting from

No pricing info

Free trial available
Credit cardless trial
Free account
Subscription based

User reviews

4.6

Value for money

Ease of use

Features

Customer support

77%

would recommend this app

4.6

243

158

Value for money

Ease of use

Features

Customer support

76%

would recommend this app

Pros

“Basically it will provide security against dangerous emails or any other sorts of SPAM.”

Fiona W.

Affiliate Marketer

Pros

“Features such as Safe Links and Safe Attachments add an extra layer of protection without significantly impacting user productivity.”

Swetha C.

Technical Program Mananger

“The platform also integrates well with other Microsoft security products, making it a strong choice for organisations already invested in Microsoft 365.”

Josh D.

IT Support Engineer

“For people who rely heavily on email for advocacy, school, benefits, medical care, and family communication, security matters.”

Michelle C.

CEO

Cons

Not enoughreviews yet

Cons

“Some of the reports, alerts, and security language can feel too technical, especially for people who are not IT professionals.”

Michelle C.

CEO

“Some advanced phishing or spoofing protections aren’t perfect and may miss high-level impersonation attacks without additional layers or tuning.”