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Proofpoint Core Email Protection vs Microsoft Defender for Office 365 Comparison (2026)

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Proofpoint Core Email Protection logo

Proofpoint Core Email Protection

Microsoft Defender for Office 365 logo

Microsoft Defender for Office 365

Overview

Proofpoint Email Protection is a computer security management software designed to help businesses identify and block threats using AI-enabled tools. It offers an advanced business email compromise (BEC) defense feature, which enables administrators to analyze various attributes including message header and senders’ IP address.

Microsoft Defender for Office 365 is a cloud-based email security software designed to help businesses automatically detect, investigate, and resolve potential email threats on a centralized platform. Supervisors can configure security policies, perform spoof checks, and maintain a record of reported incidents.

  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials
  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials

Video & Screenshots

Pricing

Starting from

Empty state illustration for "No pricing info"

No pricing info

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

Starting from

Empty state illustration for "No pricing info"

No pricing info

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

User reviews

4.2

45

5

4

3

2

1

18

21

4

1

1

  • Value for money
  • Ease of use
  • Features
  • Customer support
71%
would recommend this app

4.6

243

5

4

3

2

1

158

71

8

5

1

  • Value for money
  • Ease of use
  • Features
  • Customer support
76%
would recommend this app

Pros

“Proofpoint's Email protection is excellent in identifying and blocking phishing attacks.”
KR

Kiran R.

Vulnerability Assessor

“Good overall product; sometimes difficult to configure / customize, but surely one of the best in terms of update and protection.”
IM

Ilario M.

ICT Infrastructure Manager

“Easy integration with Outlook 365, friendly management console”
IM

Ilario M.

ICT Infrastructure Manager

Pros

“Features such as Safe Links and Safe Attachments add an extra layer of protection without significantly impacting user productivity.”
Verified reviewer profile picture

Swetha C.

Technical Program Mananger

“The platform also integrates well with other Microsoft security products, making it a strong choice for organisations already invested in Microsoft 365.”
JD

Josh D.

IT Support Engineer

“For people who rely heavily on email for advocacy, school, benefits, medical care, and family communication, security matters.”
MC

Michelle C.

CEO

Cons

“Quarantine interface is bit complex to use and manage.”
KR

Kiran R.

Vulnerability Assessor

“Some areas of Proofpoint proved to be a bit difficult to customize for our organization.”
BS

Bryson S.

Systems Administrator

“Bad customer support, sometimes too many true positives are there which can be dangerous for a firm.”
kS

kartik S.

information security engineer

Cons

“Some of the reports, alerts, and security language can feel too technical, especially for people who are not IT professionals.”
MC

Michelle C.

CEO

“Some advanced phishing or spoofing protections aren’t perfect and may miss high-level impersonation attacks without additional layers or tuning.”
MW

Mekailah W.

Ceo

“Steep learning curve when configuring advanced rules or email routing, and support documentation isn't always compatible with our usage scenario.”
AO

Alvin O.

Cyber Security Specialist

  • Vendor responds to reviews
  • Last reviewa year ago
  • Vendor responds to reviews
  • Last reviewa month ago

Key features

  • Total features41
  • API
  • Access Controls/Permissions
  • Activity Dashboard
  • Activity Monitoring
  • Activity Tracking
  • Alerts/Escalation
  • Alerts/Notifications
  • Allow/Block List
  • Anomaly/Malware Detection
  • Anti Spam
  • Anti Virus
  • Application Security
  • Authentication
  • Data Loss Prevention
  • Data Security
  • Data Synchronization
  • Data Verification
  • Email Attachment Protection
  • Email Filtering
  • Email Management
  • Email Monitoring
  • Email Routing
  • Email Tracking
  • Encryption
  • Endpoint Protection
  • Event Analysis
  • Event Logs
  • Filtering
  • Firewalls
  • Fraud Detection
  • Greylisting
  • Intrusion Detection System
  • Microsoft Outlook Integration
  • Monitoring
  • Network Monitoring
  • Network Scanning
  • Phishing Protection
  • Policy Management
  • Real-Time Analytics
  • Real-Time Monitoring
  • Real-time Alerts
  • Reporting/Analytics
  • SURLB/URIBL Filtering
  • Search
  • Spam Analysis
  • Spam Blocker
  • Spam Detection
  • Spam Quarantine
  • Threat Intelligence
  • Threat Protection
  • Threat Response
  • Vulnerability Scanning
  • Whitelisting/Blacklisting
  • Total features22
  • API
  • Access Controls/Permissions
  • Activity Dashboard
  • Activity Monitoring
  • Activity Tracking
  • Alerts/Escalation
  • Alerts/Notifications
  • Allow/Block List
  • Anomaly/Malware Detection
  • Anti Spam
  • Anti Virus
  • Application Security
  • Authentication
  • Data Loss Prevention
  • Data Security
  • Data Synchronization
  • Data Verification
  • Email Attachment Protection
  • Email Filtering
  • Email Management
  • Email Monitoring
  • Email Routing
  • Email Tracking
  • Encryption
  • Endpoint Protection
  • Event Analysis
  • Event Logs
  • Filtering
  • Firewalls
  • Fraud Detection
  • Greylisting
  • Intrusion Detection System
  • Microsoft Outlook Integration
  • Monitoring
  • Network Monitoring
  • Network Scanning
  • Phishing Protection
  • Policy Management
  • Real-Time Analytics
  • Real-Time Monitoring
  • Real-time Alerts
  • Reporting/Analytics
  • SURLB/URIBL Filtering
  • Search
  • Spam Analysis
  • Spam Blocker
  • Spam Detection
  • Spam Quarantine
  • Threat Intelligence
  • Threat Protection
  • Threat Response
  • Vulnerability Scanning
  • Whitelisting/Blacklisting

Integrations

  • Total integrationsN/A
    • Total integrationsN/A