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Top Rated Endpoint Protection Software with Mac

Last updated: May 2026

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104 software options

Jamf Protect logo

Jamf Protect

Endpoint protection software for MacOS users

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Jamf Protect is an endpoint protection software designed to help businesses monitor events across Mac devices and detect, prevent and resolve threats. The platform notifies administrators about malicious activities across scripts, applications, and users and automatically quarantines files for further analysis.

Features of Jamf Protect include log forwarding, CIS benchmarks, on-device activity analysis, threat intelligence, behavioral analytics, and more.

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ManageEngine Endpoint Central logo

ManageEngine Endpoint Central

Desktop, mobile device & patch management software

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Endpoint Central (formerly Desktop Central) from ManageEngine is an integrated desktop & mobile device management application that enables the centralized management of desktops, servers, laptops, tablets & smartphones.

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Heimdal Next-Gen Endpoint Antivirus logo

Heimdal Next-Gen Endpoint Antivirus

Next-Gen Antivirus for Unparalleled Detection and Response.

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Heimdal Next-Gen Endpoint Antivirus is an NGAV solution featuring unparalleled threat intelligence, forensics, and firewall integration for a complete endpoint detection and response approach. With it, you will not only secure your workstations but make everyone’s life easier in the process too.

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Automox logo

Automox

Cloud-based platform for patch management

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Automox is the endpoint management platform built for the era of autonomous operations

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Netwrix Endpoint Protector logo

Netwrix Endpoint Protector

Data loss prevention and endpoint protection tool

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Netwrix Endpoint Protector is a data loss prevention tool which assists businesses of all sizes with data encryption and file scanning. Key features of the platform include compliance management and reporting, policy management, device control, and sensitive data identification.

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Heimdal Ransomware Encryption Protection logo

Heimdal Ransomware Encryption Protection

An Advanced Ransomware Encryption Blocking Agent.

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Heimdal Ransomware Encryption Protection is an innovative, 100% signature-free module that provides market-leading detection of ransomware attacks, as well as remediation in case of encryption. It is effective against both fileless and file-based strains, quietly securing all your digital assets.

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Iru logo

Iru

Collapse the IT stack with Iru.

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AI-powered platform that unifies identity, endpoints, and compliance—giving IT teams time and control back.

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NinjaOne logo

NinjaOne

Unified endpoint management & IT automation platform

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NinjaOne Endpoint Management enables IT organizations of all sizes and experience levels to take a more proactive approach to IT management, which yields significant efficiency gains, improved user satisfaction and a stronger security posture.

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Tanium logo

Tanium

Autonomous IT, driven by AI and real-time intelligence

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The Tanium Autonomous IT Platform unifies endpoint management and security on a single, unified platform. Real time endpoint intelligence and AI driven automation deliver continuous visibility, control, and closed loop action across IT, cloud, mobile, and OT - accelerating decisions, lowering costs,

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Acronis Cyber Protect Cloud logo

Acronis Cyber Protect Cloud

AI-powered data protection and cybersecurity

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Acronis Cyber Protect Cloud is AI-powered cyber protection for modern MSPs, natively integrating operations management, cybersecurity and data protection in one platform.

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Acronis Cyber Protect logo

Acronis Cyber Protect

Integrated data protection and cybersecurity in one solution

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Acronis Cyber Protect brings together data protection and cybersecurity in one, easy-to-use solution.

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Rippling logo

Workforce management across HR, finance, and IT. 

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Rippling is a cloud-based workforce management system that helps businesses manage operations across HR, finance, and IT.

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Action1 logo

Patching That Just Works

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Action1 reinvents patch management with an infinitely scalable and highly secure platform configurable in 5 minutes that just works.

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1Password logo

Password manager for businesses and families

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1Password protects all company secrets such as passwords, security tokens, 2FA codes, documents, and passkeys to centralize and simplify the sign-in experience. Developers have access to features that help secure secrets and speed up workflows throughout the software development life cycle.

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GoodAccess logo

Zero Trust Architecture as a Service

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Cybersecurity platform (SASE/SSE) that enables easy Zero Trust Architecture implementation for medium enterprises, any scale.

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UTunnel VPN logo

Cloud VPN, Zero Trust Network Access, and Mesh Networking

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UTunnel offers easy-to-deploy Cloud VPN, Zero Trust Access, and Mesh Networking solutions. Safeguard your business with secure remote access and encrypted site-to-site connectivity between distributed business networks. Deployment in minutes, Robust Support, and Affordable Pricing Plans!

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ThreatLocker logo

Zero Trust Platform

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ThreatLocker is a Zero Trust platform that blocks unknowns, enforces least privilege, and protects endpoints from cyber threats.

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Admin By Request logo

Local admin rights, managed.

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Endpoint privilege management with just-in-time admin elevation, full auditing, and secure remote access for Windows, macOS, and Linux. Anti-malware file scanning, SSO and MFA enforcement, ML and AI automation, temporary local admin accounts, and a full inventory and detailed auditlog.

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SentinelOne logo

Protect your Endpoints, Cloud, and Data

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SentinelOne delivers autonomous cybersecurity powered by AI, enabling real-time prevention, detection, and response to threats across endpoints, cloud workloads, and identity systems—empowering organizations to stay ahead of cyberattacks with speed, visibility, and control.

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GateKeeper Enterprise logo

Shared PC authentication, proximity, 2FA/MFA wireless token.

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GateKeeper Enterprise is an access management software which helps businesses in healthcare, manufacturing, and other industries handle proximity-based authentication for PCs and websites. It enables organizations to automatically lock employees’ unattended devices and securely store passwords.

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VMware Cloud Director Availability logo

Streamline your Cloud Migration and Disaster Recovery

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VMware Cloud Director Availability provides replications and failover at a vApp or virtual machine level. VMware Cloud Director Availability is a unified solution, that provides on-premises to cloud and cloud to cloud onboarding, migration, and disaster recovery for multi-tenant cloud sites.

Read more about VMware Cloud Director Availability

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Password Depot logo

The oustanding password manager.

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Password Depot is a password management solution that helps businesses ensure optimal protection for sensitive data. The application allows users to safeguard passwords, documents, identities, debit or credit cards, and more with AES Rijndael 256 double encryption. It generates secure passwords and automates data entry, eliminating the need for manual typing. Users can access their passwords across multiple devices, including Windows, Mac, iOS, and Android.

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DNSFilter logo

Cloud-based cybersecurity and network monitoring platform

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DNSFilter is a cybersecurity management software that enables enterprises, K-12 schools, and universities to detect online security threats and malware using artificial intelligence (AI) technology, machine learning (ML) algorithms, and content filtering capabilities.

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Malwarebytes for Business logo

Complete cybersecurity software for businesses

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Malwarebytes is a network security software that enables businesses to identify and detect potential cyberthreats across networks or enterprise servers. The cloud-based Malwarebytes Nebula platform lets administrators gain visibility into threat patterns from the centralized dashboard.

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INLYSE Malware.AI logo

VISUAL AI BASED MALWARE DETECTION

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INLYSE Malware.AI is a revolutionary visual AI-based malware detection solution that utilizes cutting-edge technology to convert files into graphical representations and analyze them comprehensively for any signs of malware.

Read more about INLYSE Malware.AI

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