Smartsheet vs RealTime-CTMS

Trello

Google Sheets

monday.com

Clinical Conductor CTMS

CRIO

Data+

Compare Smartsheet and RealTime-CTMS based on features, pricing, verified reviews, integrations & more on GetApp. Find out which software is best for your business in 2026.

monday.com is a cloud-based Work OS, where teams create workflow apps in minutes to run their processes, projects, and everyday work. Teams shape workflows and projects, code-free, with a platform that adapts to shifting needs, liberates teams from manual grunt work, and connects teams in a collaborative work space.

Trello is a project management tool that helps teams organize and manage their tasks. It caters to a range of industries and teams, from marketing to engineering. Trello's simple and intuitive interface makes it easy for any team to get started and stay on top of their work.

Google Sheets is a cloud-based spreadsheet platform designed to help businesses of all sizes collaborate with clients and partners to create and edit data on spreadsheets.

Smartsheet, an online work execution platform, empowers organizations to plan, track, automate, and report on work. Over 80,000 brands rely on Smartsheet for project and work management because of its easy-to-use interface, real-time gantt charts and dashboards, and work automation features.

Access Controls/Permissions

Accounting

Activity Dashboard

Activity Planning

Activity Tracking

Ad hoc Reporting

Agile Methodologies

Alerts/Notifications

Analytics

Approval Process Control

Approval Workflow

Asset Tracking

Assignment Management

Audit Trail

Availability Management

Backlog Management

Bar Chart

Bid Management

Billing & Invoicing

Brainstorming

Brand Management

Budget Management

Budget Tracking

Budgeting/Forecasting

Bug Tracking

Business Process Automation

Calendar Management

Calibration Management

Campaign Analytics

Campaign Management

Campaign Planning

Capacity Management

Change Management

Change Order Management

Channel Management

Charting

Client Management

Client Portal

Collaboration Tools

Color Codes/Icons

Commenting/Notes

Commercial

Communication Management

Compliance Tracking

Contact Database

Content Management

Contract/License Management

Contractor Management

Cost Estimating

Cost-to-Completion Tracking

Customizable Dashboard

Customizable Fields

Customizable Reports

Customizable Templates

Dashboard

Dashboard Creation

Data Connectors

Data Import/Export

Data Synchronization

Data Tabulation

Data Visualization

Deadline Management

Dependency Tracking

Digital Asset Management

Discussions/Forums

Display Ad Management

Document Management

Document Review

Document Storage

Drag & Drop

Due Date Tracking

Electronic Data Capture

Email Management

Email Reminders

Employee Management

EMR/EHR

Equipment Tracking

Event Calendar

Event Management

Expense Management

Expense Tracking

Feedback Management

File Management

File Sharing

File Transfer

Financial Management

Financial Reporting

For AEC Industry

For IT Project Management

For Residential

Forms Automation

Forms Creation & Design

Forms Management

Functions/Calculations

Gantt/Timeline View

Goal Setting/Tracking

HIPAA Compliant

HR Management

Smartsheet

Android

Web-based

iPad

iPhone

Compliance Coordinator

It's been great having so many templates to choose from and customize. Awesome that it can be integrated with MS Teams.

Marketing Manager

I love the ease to customize your sheet for whatever you need and however you like it. Love being able to switch around columns and sort rows so quickly too.

Head of Program Operations

The project being web-based helps to share information with other members of the team. The ability to export to various formats, as well as get team updates is a huge benefit.

Client Delivery Associate

Overall, the experience is positive - strong tools, robust features, easy to learn. I would recommend this to anyone who needs to have data interact with multiple systems and user types.

Quality and Governance manager 

I am a big fan of smart sheet. Not only is the tool extremely capable for more complex project needs but the service team is also extremely helpful.

Digital Marketing Director

A good advantage is the presence of a strong community that helps to find answers quickly. Smartsheet also makes quite easy to share results with teammates.

Director of Digital Engagement

I then took the Smartsheet training to be certified and that opened my eyes to the power of the tool (and also to the fact that the sheets I hated were users in our company using it very, very WRONG).

Marketing

I think Smartsheet is a great tool for several reasons, but one of the most important is the ability to collaborate with your team in real time.

Research Coordinator

I especially like the ability to assign tasks to a certain person. The calendar feature has also been great to track past and upcoming events.

QA  Coordinator

You can pull off amazing things if you sit down and build it. I was able to build a completely automated revenue and labor estimator that shows me how profitable each member of my team is.

Product Manager

Smartsheet is super dedicated to project management...their templates are quite useful and run the gamut from gantt charts to expense reports.

Junior Content Producer

It's shear-ability, ease to use, and major effectiveness when project managing. It's great to control every step of the way.

Director of Solutions

I find answers to my questions quickly in the Smartsheet community and existing templates save me a great deal of time...and make me look smart.

director

Collaborative; User friendly; Relatively inexpensive; Good Dashboard (once you understand it).

The only complaint that I have is that if the spreadsheet is very large, the page can be slightly laggy.

Technical Analyst

Some features seem to be missing or limited features available.

Director, Business Solutions & IT

Tools like Zapier make it easy to integrate with, and you can also upgrade to a live data connector to visualize your data in a tool like tableau.

Senior Director of Operations

Visually did not work for some users in my organization. Was confusing on what tasks needed to be completed.

Smartsheet screenshot: Smartsheet multiple platform

Smartsheet screenshot: Smartsheet real-time dashboard

Smartsheet screenshot: Smartsheet content collaboration

Smartsheet screenshot: Smartsheet Grid view

Smartsheet screenshot: Smartsheet Gantt view

Smartsheet screenshot: Smartsheet card view

Freelancers

Large Enterprises

Mid Size Business

Non Profit

Public Administrations

Small Business

Clinical Conductor CTMS (CC CTMS) is the most used by research sites worldwide. Part of the CCTrialSuite, CC CTMS is helping leading hospitals and health systems of every size or complexity to maximize their decentralized trial results. Optimize recruiting, enrollment, finances, reporting and more.

CRIO, the leader in eSource technology, is a health tech company helping pharma, biotech, research sites, and academic research centers streamline regulatory workflows with one system that delivers a single source of clinical data capture.

Data+ Research is a fully compliant & customizable application development platform for health and life-science industries, offering a wide range of apps for clinical data management, drug development, patient registries, biobank and lab management and more

RealTime-CTMS is an end-to-end clinical trial management system designed to streamline clinical study information and company processes

21 CFR Part 11 Compliance

Clinical Study Management

Compliance Management

Customizable Forms

Data Capture and Transfer

Digital Signature

Enrollments/Onboarding

Monitoring

Patient Management

Patient Monitoring

Patient Recruiting

Progress Tracking

Randomization

Real-Time Data

Real-Time Monitoring

Real-Time Reporting

Reminders

Reporting & Statistics

Role-Based Permissions

Scheduling

Third-Party Integrations

Trial Design

User Management

Workflow Management

RealTime-CTMS

Clinical Research Quality Control Specialist

I am fairly new to using RealTime but my company has used it for quite a while. I'm impressed with the software and especially very impressed with the customer service.

Study Start-Up and Regulatory Manager

I love how the accounting side helps link patient visits to reimbursements. This has made my job so much better for AP/AR and tracking payments.

Director, Business Operations

Very user friendly and easy to navigate. I really like the University section where you can view videos of how to do things.

CEO & Research Director 

The new customized reloadable cards that we give our patients are a wonderful addition and has saved us lots of time and money, plus take us to a new level of professionalism.

Patient Recruitment Specialist

On top of that, I have had a great costumer service experience. Every team member I work with goes above and beyond to make sure all my concerns are addressed as soon as possible.

Smartsheet vs RealTime-CTMS Comparison (2026)

Smartsheet vs RealTime-CTMS Comparison (2026)

Smartsheet

RealTime-CTMS

Overview

Video & Screenshots

Pricing

User reviews

Key features

Integrations

Alternatives