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Secure Email Gateway Software with Compliance Management (2026)

Last updated: March 2026

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16 software options

SpamTitan logo

Anti-spam filter for business email. Vital email security.

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SpamTitan is an anti-spam email security solution that identifies & blocks phishing, malware, spear phishing, malicious and spam emails to protect business email, with multi-layered analysis and authentication. 5 Star product with great pricing and amazing front line support

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NeoCertified logo

Secure email for confidential & sensitive documents

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NeoCertified provides secure email encryption with Outlook integration for businesses of all industries, including healthcare, finance, legal & education

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Mailock logo

Secure emails with encryption and recipient authentication

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Exchange confidential information securely with the Mailock Enterprise secure email gateway. Encrypt messages and authenticate recipients.

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Libraesva Email Security logo

Exceptional Email Security

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Libraesva Email Security stops known and emerging email threats from reaching their target, so you only receive legitimate messages. It provides exceptional email security by integrating cloud email and a secure email gateway with Libraesva’s unique Adaptive Trust Engine.

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Avanan logo

Email Security — Reinvented

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Avanan catches the advanced attacks that evade default and advanced security tools. Its invisible, multi-layer security enables full-suite protection for cloud collaboration solutions such as Office 365, G-Suite, and Slack. The platform deploys in one click via API.

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Sealit logo

Full Security - Just 1 Click.

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Sealit protects your data, no matter how it's shared. End-to-end email and file encryption for small businesses or individuals.

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Virtru logo

Cloud-based data privacy and security platform

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Virtru offers a range of data protection products that provide encryption, access controls, key management, and persistent audit to meet security and privacy needs. Supports HIPAA, GDPR, CCPA, ITAR, CJIS, NIST, FERPA and CCMC compliance & integrates seamlessly into the platforms you already use.

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Inxmail logo

Email marketing software to create newsletters & emails

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Inxmail is the service-oriented tech specialist for secure, data-driven communication in email marketing.

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Trustifi logo

Protect Your Business Emails with AI-Powered Security

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Email security solution that helps manage threat detection, regulatory compliance, data encryption, whitelisting/blacklisting, and more.

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Cisco Secure Email logo

Cloud-based email security tool for preventing cyberattacks

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Cisco Secure Email is a cloud-based email security software designed to help businesses of all sizes provide protection against malicious files, malware, ransomware, phishing attacks, spoofing, and other cyber threats. It enables organizations to streamline data loss prevention (DLP) and encryption processes to safeguard critical business information.

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ContentCatcher logo

Cloud-based email security, phishing protection & anti-spam

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ContentCatcher is a web-based SaaS solution offering email security, encryption, anti-spam, phishing protection and compliant archiving to assist organizations of all levels to combat and mitigate malicious email threats, with features including anti-virus, filtering, URL defense, reporting and more

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365 Total Protection logo

Email security management for Microsoft Office 365

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365 Total Protection is an email security & compliance solution for Microsoft Office 365 with features for tracking emails in real time, handling infomail, blocking spam, filtering for compliance, defending against threats, black & whitelisting, archiving emails, analyzing communications, & more

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Sophos Email logo

Software for managing email encryption and secure networks

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Sophos Email is a cloud-based software designed to help businesses establish secure email networks and ensure protection from malware, intrusion, unauthorized access, and other online threats. The application includes anti-ransomware technology, which enables organizations to stop boot-record and ransomware attacks using behavioral analysis.

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modusCloud logo

Cloud email security, encryption, and archiving

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modusCloud is a cloud email security solution with tools for spam detection, threat monitoring, email archiving, phishing detection, and more. The cloud-based platform offers features including filtering, continuity, encryption, and archiving in order to provide businesses with email protection.

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Clearswift SECURE Email Gateway logo

Computer security and secure email gateway software

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Clearswift SECURE Email Gateway is a computer security software that helps busiensses manage data encryption, compliance, threat protection, and other operations on a centralized platform. It enables staff members to utilize the inspection engine to disassemble communication and manage data security across zip files and embedded documents.

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iQ.Suite aaS logo
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Enterprise email management & security solution for M365

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iQ.Suite aaS is a cloud-based enterprise email management and security solution for companies using Microsoft 365. It offers a comprehensive set of features including content-driven encryption, insider threat detection, wrong recipient protection, and more. iQ.Suite aaS offers malware and spam detection to minimize risk and secure emails from unauthorized access. Additionally, to ensure company policies are met, this solution can be used to apply business policies to email communications.

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