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OpenClinica vs ResearchManager Comparison (2026)

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OpenClinica

ResearchManager

Overview

OpenClinica is a compliant, all-in-one clinical data management platform offering electronic data capture with collaborative drag and drop interface for designing studies, randomization and supply management, patient reported outcomes (ePRO & eCOA), plus reporting tools with chart visualizations

The Clinical Research Suite is an online platform tailored for managing clinical trials, facilitating organizations in planning, strategizing, and executing life science research. It empowers researchers to collect and analyze data in standardized formats, optimizing scientific research and decisio

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Video & Screenshots

Pricing

Starting from

1000

Per month

Free trial available
Credit cardless trial
Free account
Subscription based

Starting from

No pricing info

Free trial available
Credit cardless trial
Free account
Subscription based

User reviews

4.6

Value for money

Ease of use

Features

Customer support

85%

would recommend this app

4.2

118

Value for money

Ease of use

Features

Customer support

62%

would recommend this app

Pros

“Our research on the efficacy and safety of medications was supported by OpenClinica's reporting and analytics capabilities, which gave us insights into patient demographics, treatment outcomes, and adverse events.”

Angelica B.

University Intern

“The support provided by the Openclinica team cannot be beat. If I may list two things, the OC system is incredibly user friendly.”

Adam P.

Data Manager

“Some training sessions go really well, especially when you are with someone hire up on the support team, but there have been many sessions where the trainer is referring to a manual to instruct me on my question and I lose a lot of my "training hours" waiting for them to figure it out and then pass on the information.”

Bethany F.

CDM II

Pros

In other systems, I have seen a more practical solution where each data point has a default status of “SDV not performed”, which can then be changed to “SDV performed” or “SDV not OK”. If “SDV performed” is selected and the site subsequently changes the entered data, the status automatically changes to “Data changed after SDV”.

Marta L.

CRA

“Value for money, affordable subscription model, customer support, ability to customize.”

Piotr G.

CEO

“Currently, it is only visible that a query has been raised for a given parameter, but the actual status is not clear.”

Marta L.

CRA

Cons

“The randomization tool is pretty sophisticated but it also costs extra and whenever you need to do updates to the tool it's a much more difficult process then simply publishing it to test.”

Bethany F.

CDM II

“This also adds layers of difficulty to the testing.”

Bethany F.

CDM II

Cons

“From a monitor’s perspective, the weakest point is that SDV can only be performed for closed visits, and only at the page level rather than for individual data points.”

Marta L.

CRA

“The user interface can feel somewhat complex for first-time users, and some advanced functions are not immediately intuitive.”

Mateusz L.

Data Science Analyst

“There is no real-time troubleshooting option available. If the issues issnt addressed in the FAQ an email needs to be sent and in most of the cases the response is in dutch.”

Gabriella M.

Research Director