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MasterControl Quality Excellence vs Isolocity Comparison (2026)

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MasterControl Quality Excellence

Isolocity

Overview

MasterControl Qx, the #1 QMS for life sciences, simplifies FDA, EMA, and ISO compliance, and speeds quality products to market.

Isolocity is a top-rated eQMS for all industries. Isolocity strives to streamline compliance through automated workflows that provide valuable insights to help our users make informed decisions.

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Platforms supported

Web-based
iPhone app
Android app
Windows Phone app

Typical customers

Freelancers
Small businesses
Mid size businesses
Large enterprises

Customer support

Phone
Online
Knowledge base
Video tutorials

view more detailsview details

Video & Screenshots

Pricing

Starting from

12000

/user

Free trial available
Credit cardless trial
Free account
Subscription based

Starting from

/user

Per month

Free trial available
Credit cardless trial
Free account
Subscription based

User reviews

4.5

540

297

206

Value for money

Ease of use

Features

Customer support

68%

would recommend this app

4.6

Value for money

Ease of use

Features

Customer support

88%

would recommend this app

Pros

“It is a reliable and mature solution for managing quality systems in regulated environments and it supports digital transformation initiatives effectively. While there are areas that could be improved in terms of usability and flexibility, the platform provides strong compliance support and helps standardize quality processes across different functions and sites.”

Simone B.

Quality compliance specialist

“MasterControl Quality Excellence is a solid and comprehensive eQMS platform, particularly suitable for highly regulated industries such as pharmaceuticals and medical devices.”

Simone B.

Quality compliance specialist

“Some modules could benefit from a more modern and user-friendly interface, and system performance may occasionally slow down when handling large processes or extensive datasets.”

Simone B.

Quality compliance specialist

Pros

“Some modules do not fully align with operational needs; therefore, paper-based records are still used to bridge these gaps and ensure continued compliance with GMP requirements.”

Tal N.

Head of RA and Compliance

“Audit reports are limited as would like a score assigned to results instead of pass/fail and escalating from a non-conformance to a CPAR is duplicating the information, it should automatically transfer all the info over.”

Joan C.

Quality Manager

“This system is well designed and helps to ensure audit readiness when it comes to any certification system used.”

Robert F.

Quality Assurance Manager

Cons

“Some of the pain points are the cost of licensing, not having the ability for multiple collaborators to edit the same document simultaneously, and search functionality being tough for users who aren't as familiar with document numbers/names.”

Johana A.

Jr MasterControl Sys Admin

“The performance on "on prem" version, pdf publishing time and constant issues with pdf not beeing generated, issues with custom forms created by MC.”

Michal M.

IT QMS Software Administrator

“With the cloud and licensing model changes, we've seen a dramatic increase in licensing fees, while simultaneously losing the ability to implement custom solutions and assign user rights freely.”

Jeremy R.

Sr. Manager, SQA

Cons

“Some wait times were noticeable, and there were instances where pop-up windows could not be closed without using Ctrl-based keyboard commands, affecting the overall user experience.”

Ryan P.

QAP

“The user interface can feel a bit dated, which creates a slight learning curve when onboarding new team members to the system”

Cory F.

Director of Operations

“Some of the features are clunky, like the Document index doesn't sort in procedure # order, doesn't save once sorted, so every time you leave the screen and come back you need to do a re-sort.”

Thomas P.

Quality and Compliance Manager