App comparison
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Macro
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Based on GetApp‘s extensive, proprietary database of in-depth, verified user reviews
Cloud-based electronic data capture for clinical research
Last updated: March 2026
Macro Alternatives & Competitors (2026)
Top 3 free alternatives
EDGE
Real-time clinical trial management with in-depth reporting
0.3
Value for money
Starting price
0.6
Functionality
21 CFR Part 11 Compliance
5/5
Appointment Management
5/5
Access Controls/Permissions
4.7/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
RealTime-CTMS
Cloud-based clinical trial management system
0.2
Value for money
Starting price
0.8
Functionality
Audit Trail
5/5
21 CFR Part 11 Compliance
4.8/5
Clinical Study Management
4.8/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
ClinCapture
Configurable EDC platform for sponsors and CROs
0.2
Value for money
Starting price
0.8
Functionality
Access Controls/Permissions
5/5
Approval Process Control
5/5
Audit Management
4/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
ShareCRF
EDC software for clinical research
Value for money
No pricing info
Starting price
0.7
Functionality
Audit Trail
4.8/5
Clinical Study Management
4.4/5
21 CFR Part 11 Compliance
3.8/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
Castor EDC
The top-rated EDC system in the world *EDC + ePRO + eConsent
Value for money
No pricing info
Starting price
0.6
Functionality
CRF Tracking
5/5
Clinical Study Management
4.7/5
21 CFR Part 11 Compliance
4.6/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
Researchmanager – Clinical Research Suite
EDC, CTMS, eTMF, ePRO, RTSM, eConsent, RIMS, LIMS
0.5
Value for money
No pricing info
Starting price
0.1
Functionality
Access Controls/Permissions
4.5/5
Audit Trail
4.3/5
21 CFR Part 11 Compliance
3.8/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.1
Value for money
No pricing info
Starting price
0.2
Functionality
21 CFR Part 11 Compliance
4.6/5
Audit Trail
4.5/5
Clinical Study Management
4/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.1
Value for money
No pricing info
Starting price
0.5
Functionality
Activity Tracking
5/5
Business Process Automation
5/5
Audit Management
4.9/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
Value for money
No pricing info
Starting price
0.3
Functionality
Clinical Study Management
5/5
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.2
Value for money
Starting price
0.4
Functionality
Customizable Fields
4.8/5
CRF Tracking
4.7/5
21 CFR Part 11 Compliance
4.7/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.3
Value for money
Starting price
0.5
Functionality
Audit Trail
5/5
21 CFR Part 11 Compliance
4.7/5
Clinical Study Management
4.7/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
Value for money
No pricing info
Starting price
0.4
Functionality
21 CFR Part 11 Compliance
5/5
Audit Trail
5/5
21 CFR Part 11 Compliance
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.2
Value for money
Starting price
0.5
Functionality
21 CFR Part 11 Compliance
5/5
Audit Trail
5/5
API
4/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.2
Value for money
Starting price
0.2
Functionality
Audit Trail
4.8/5
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.3
Value for money
No pricing info
Starting price
0.9
Functionality
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Activity Dashboard
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.1
Value for money
Starting price
0.7
Functionality
21 CFR Part 11 Compliance
4.9/5
Audit Trail
4.3/5
Access Controls/Permissions
4/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.3
Value for money
Starting price
0.9
Functionality
21 CFR Part 11 Compliance
4.8/5
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
0.2
Value for money
No pricing info
Starting price
1.1
Functionality
Audit Trail
5/5
Clinical Study Management
5/5
21 CFR Part 11 Compliance
4.7/5
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
1.6
Value for money
Starting price
0.6
Functionality
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Activity Dashboard
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5
4.6
Value for money
Starting price
3.9
Functionality
21 CFR Part 11 Compliance
N/A
Access Controls/Permissions
N/A
Activity Dashboard
N/A
Top Features
Data Import/Export
5/5
Data Verification
5/5
Data Capture and Transfer
4.5/5