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Integration Software with AS2 Capability (2026)

Last updated: March 2026

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25 software options

MuleSoft Anypoint Platform logo

The complete platform for SOA, SaaS integration & APIs

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MuleSoft provides comprehensive integration solutions tailored to the needs of many industries and business use cases with over 3,500 production deployments.

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Boomi logo

Cloud Integration Platform

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Eliminate technology fragmentation by integrating all applications. Empower IT and business teams to quickly connect your business with no-code/low-code tools, including a drag-and-drop interface, pre-built connectors, and data mapping infused with intelligence from the Boomi user community.

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Cleo Integration Cloud logo

Secure Integration and Data Movement Platform

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Cleo Integration Cloud (CIC) is a cloud-based integration platform, purpose-built to design, build, operate and optimize critical ecosystem integration processes.

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1 EDI Source logo

Complete EDI Software Solutions and Expert In-House Support

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1 EDI Source, an Epicor solution provides EDI integration for your ERP tailored to your needs. The industry standard for exchanging data between vendors and customers is automated communication through the use of EDI ERP Integration. Gain real-time visibility and automation with our integration

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ConnectPointz logo

Electronic data interchange (EDI) and integration software

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EDI, API or SOAP. ConnectPointz is designed to help enterprises organize and exchange business data with trading partners. It allows employees to communicate with merchants, track customers’ shopping cart activities, and manage sales across various online channels including Amazon, eBay and more

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Iguana logo

Integration Engine for healthcare information exchange

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Iguana is the only enterprise-calibre integration engine built specifically to handle the requirements of modern healthcare.

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Celigo Integrator.io logo

Integration Platform-as-a-Service (iPaaS) software

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Celigo is an Integration Platform-as-a-Service (iPaaS) software designed to help organizations integrate and connect with multiple third-party systems to automate various business processes across applications.

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Babelway logo

The Future of B2B Integration

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Babelway is the future of B2B integration. Take control of partner integration with a powerful enterprise-grade platform that's as easy to use as an online app.

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CData Arc logo

B2B Integration Made Easy

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CData Arc is integration and managed file transfer software designed to help businesses connect applications and automate electronic data interchange (EDI) processes using a visual workflow designer on a drag-and-drop interface.

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eiPlatform logo

Enterprise integration and interface management solution

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PilotFish’s eiConsole for Healthcare Interface Engine IDE has built-in support for all versions of HL7 2.x, 3.x, extended and non-standards compliant versions. We also have built-in support for DICOM, CCD/CDA, FHIR and X12 EDI.

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Lobster Data World logo

Connecting People & Data for a Better Future.

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Lobster is a 360° digital ecosystem that streamlines data integration, orchestration, and connectivity across enterprises.
The Lobster Data Platform, Data Network and a growing portfolio of plug-and-play Lobster Data Products build our Lobster Data World.

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Netix Flow logo

Simplified Supply Chain Management

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Netix Flow helps to optimize your procure-to-pay process by automating the flow of business-critical documents into your existing third-party systems. Giving you end-to-end visibility and increased efficiency of your supply chain.

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Missing Link logo

MissingLink, the automated, flexible procure-to-pay solution

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We offer a full turnkey solution if you want to automate incoming sales or outgoing purchase orders. Missing Link helps reduce the workload on your team and ensures a successful rollout to your base.

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VL OMNI logo

Connecting data and transforming businesses

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VL OMNI is a cloud-based EU-GDPR compliant platform for agile and scalable iPaaS data integration. It enables managers to create strategic data integrations that maintain a central point of data truth.

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Zenbridge logo

We make integrations easier.

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Send & receive EDI using easy-to-use APIs. Save your company from EDI nightmares.

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Link logo

Link is a fully managed business integration platform.

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Link by Bizbrains is a cloud-based integration platform that helps businesses optimize data connectivity between platforms, partners, and internal systems.

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Adeptia Connect logo

Self-serve capabilities for non-technical business users

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Adeptia Connect paves a shorter path to innovation and growth through its uniquely designed AI-powered data mapping, self-service integration, and large file data ingestion capability.

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X4 BPMS logo

Automated business process management

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X4 BPMS is an automated business process management solution designed to help users model, technically implement, execute, and monitor all business processes

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Tranzactor logo

Integration platform for streamlining trucking logistics

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Tranzactor is a cloud-based suite of integration solutions designed to help businesses in logistics, intermodal, trucking, and warehousing sectors automate processes related to data transformation, decision support, and electronic data interchange

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Statelake logo

Integration platform for connecting multiple applications

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Statelake is a middleware integration platform designed to connect systems and automate data exchange between applications, databases, and devices for enterprises. It connects your systems, internal and external, old and new, enabling cost-effective data and process automation.

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Business Integration Suite logo

SEEBURGER Business Integration Suite - Hybrid Integration

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SEEBURGER Business Integration Suite (BIS) is the hybrid integration platform to provide integration across all scenarios, including API integration, API Management B2B/EDI, MFT, E-Invoicing, IoT and ERP integration. BIS can be deployed on-premises, in the various clouds, or in a mix of the above.

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WebEDI logo
(0)

Experience automation across the entire supply chain.

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ecosio's Web EDI boosts supply chain efficiency by providing partners with an easy-to-use platform to exchange automated messages. Meanwhile, all technical tasks are handled by ecosio's EDI experts.

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E-invoicing and Peppol logo
(0)

Eliminating e-invoicing issues with minimum effort

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Stay compliant with current e-invoicing legislation and benefit from effortless automation with E-invoicing as a Service from ecosio.

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EDI as a Service logo
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Maximum automation. Minimum effort

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ecosio's EDI as a Service solution provides clients with "Connections That Work". From technical setup to ongoing operation, ecosio's EDI and e-invoicing experts take care of all B2B integration tasks, enabling clients to focus on what they do best.

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OpenText Trading Grid logo
(0)

Cloud-based EDI integration solution

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OpenText Trading Grid is an enterprise software solution that allows traders to view and interact with multiple market data feeds at once. The software also allows traders to customize their trading experience by adding pre-built charting tools, technical indicators, and other features.

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