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MasterControl Quality Excellence vs Vanta Comparison (2026)

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Good recommendations?

MasterControl Quality Excellence logo

MasterControl Quality Excellence

Vanta logo

Vanta

Overview

MasterControl Qx, the #1 QMS for life sciences, simplifies FDA, EMA, and ISO compliance, and speeds quality products to market.

Vanta helps 9,000+ teams start and scale their security programs, like Atlassian, Quora to Chili Piper and incident.io. Automate 35+ compliance frameworks, centralize GRC, accelerate security reviews, and build trust.

  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials
  • Platforms supported
  • Web-based
  • iPhone app
  • Android app
  • Windows Phone app
  • Typical customers
  • Freelancers
  • Small businesses
  • Mid size businesses
  • Large enterprises
  • Customer support
  • Phone
  • Online
  • Knowledge base
  • Video tutorials

Video & Screenshots

Pricing

Starting from

12000

/user

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

Starting from

Empty state illustration for "No pricing info"

No pricing info

  • Free trial available
  • Credit cardless trial
  • Free account
  • Subscription based

User reviews

4.5

576

5

4

3

2

1

313

223

38

2

0

  • Value for money
  • Ease of use
  • Features
  • Customer support
68%
would recommend this app

4.2

33

5

4

3

2

1

21

6

1

0

5

  • Value for money
  • Ease of use
  • Features
  • Customer support
73%
would recommend this app

Pros

“It is a reliable and mature solution for managing quality systems in regulated environments and it supports digital transformation initiatives effectively. While there are areas that could be improved in terms of usability and flexibility, the platform provides strong compliance support and helps standardize quality processes across different functions and sites.”
Verified reviewer profile picture

Simone B.

Quality compliance specialist

“MasterControl Quality Excellence is a solid and comprehensive eQMS platform, particularly suitable for highly regulated industries such as pharmaceuticals and medical devices.”
Verified reviewer profile picture

Simone B.

Quality compliance specialist

“Some modules could benefit from a more modern and user-friendly interface, and system performance may occasionally slow down when handling large processes or extensive datasets.”
Verified reviewer profile picture

Simone B.

Quality compliance specialist

Pros

“It saves a ton of time when dealing with compliance and security tasks, especially compared to doing everything manually.”
MP

Mario P.

QA Engineer

“The dashboard and easy progress bar indicating where work is still needed guides you through everything you need to know and achieve.”
AB

Alex B.

Managing Director

“Vanta really takes the stress out of managing compliance and security by automating so much of the work.”
MP

Mario P.

QA Engineer

Cons

“Some of the pain points are the cost of licensing, not having the ability for multiple collaborators to edit the same document simultaneously, and search functionality being tough for users who aren't as familiar with document numbers/names.”
JA

Johana A.

Jr MasterControl Sys Admin

“The performance on "on prem" version, pdf publishing time and constant issues with pdf not beeing generated, issues with custom forms created by MC.”
MM

Michal M.

IT QMS Software Administrator

“With the cloud and licensing model changes, we've seen a dramatic increase in licensing fees, while simultaneously losing the ability to implement custom solutions and assign user rights freely.”
Verified reviewer profile picture

Jeremy R.

Sr. Manager, SQA

Cons

“The pricing was too high and we still had to handle auditor ourselves which we were not vvery fond of doing.”
JD

Jana D.

Ops Manager

“I needed to do a chargeback after they refused to return the money even though I notified them same day they were previously told I would not renew.”
JS

Joel S.

CEO

“Also, they make very difficult to reach them when you have a problem.”
JS

Joel S.

CEO

  • Vendor responds to reviews
  • Last review5 days ago
  • Vendor responds to reviews
  • Last review10 months ago

Key features

  • Total features132
  • API
  • Access Controls/Permissions
  • Access Expiration Management
  • Activity Dashboard
  • Activity Tracking
  • Alerts/Escalation
  • Alerts/Notifications
  • Approval Process Control
  • Archiving & Retention
  • Assessment Management
  • Asset Tracking
  • Attestation
  • Audit Management
  • Audit Performance
  • Audit Planning
  • Audit Trail
  • Automated Scheduling
  • Bills of Material
  • Business Process Control
  • Calibration Management
  • Change Management
  • Collaboration Tools
  • Commenting/Notes
  • Communications Management
  • Complaint Management
  • Compliance
  • Compliance Management
  • Compliance Tracking
  • Configurable Workflow
  • Consent Management
  • Content Management
  • Corrective and Preventive Actions (CAPA)
  • Cross-system Integration
  • Customer Complaint Tracking
  • Customizable Forms
  • Customizable Reports
  • Customizable Templates
  • Dashboard
  • Dashboard Creation
  • Data Governance
  • Data Import/Export
  • Data Security
  • Data Storage Management
  • Data Synchronization
  • Data Visualization
  • Defect Tracking
  • Design Management
  • Digital Signature
  • Document Automation
  • Document Capture
  • Document Check-in/Check-out
  • Document Classification
  • Document Coding & Control
  • Document Control
  • Document Generation
  • Document Lifecycle Management
  • Document Management
  • Document Review
  • Document Storage
  • Document Templates
  • Documentation Management
  • EDI
  • Electronic Signature
  • Email Alerts
  • Enterprise Risk Management
  • Equipment Management
  • Event Logs
  • Evidence Management
  • Exceptions Management
  • Execution
  • FDA Compliance
  • File Management
  • File Sharing
  • For Engineering Documents
  • For Healthcare
  • Forms Management
  • Full Text Search
  • Generative AI
  • Governance
  • HIPAA Compliant
  • ISO Compliance
  • ISO Standards Management
  • IT Risk Management
  • Incident Management
  • Inspection Management
  • Internal Controls Management
  • Inventory Management
  • Issue Management
  • Issue Tracking
  • Log Management
  • MES
  • Machine and equipment
  • Maintenance
  • Maintenance Management
  • Maintenance Scheduling
  • Manufacturing Software
  • Mobile Access
  • Monitoring
  • Multi-Language
  • Multi-Location
  • Multiple Format Support
  • Nonconformance Tracking
  • Onboarding
  • Operational Risk Management
  • Order Management
  • PCI Assessment
  • PCI Compliance
  • Performance Analysis
  • Performance Metrics
  • Policy Creation
  • Policy Library
  • Policy Management
  • Policy Training
  • Predictive Analytics
  • Prioritization
  • Product Data Management
  • Production Scheduling
  • Project Management
  • Quality Assurance
  • Quality Control
  • Quality Management
  • Real-Time Analytics
  • Real-Time Data
  • Real-Time Monitoring
  • Real-Time Notifications
  • Real-Time Reporting
  • Real-Time Updates
  • Remediation Management
  • Reminders
  • Reporting & Statistics
  • Reporting/Analytics
  • Response Management
  • Revision History
  • Risk Alerts
  • Risk Analysis
  • Risk Assessment
  • Risk Management
  • Risk Methodology
  • Risk Reporting
  • Risk Scoring
  • Role-Based Permissions
  • Root Cause Analysis
  • Routing
  • Rules-Based Workflow
  • Safety Management
  • Scheduling
  • Search/Filter
  • Secure Data Storage
  • Security Auditing
  • Self Service Portal
  • Sensitive Data Identification
  • Single Sign On
  • Status Tracking
  • Supplier Management
  • Supplier Quality Control
  • Surveys & Feedback
  • Task Management
  • Template Management
  • Third-Party Integrations
  • Traceability
  • Training Management
  • Trend Analysis
  • User Management
  • Vendor Management
  • Version Comparison
  • Version Control
  • Version Rollback
  • Vulnerability Scanning
  • Workflow Management
  • Total features98
  • API
  • Access Controls/Permissions
  • Access Expiration Management
  • Activity Dashboard
  • Activity Tracking
  • Alerts/Escalation
  • Alerts/Notifications
  • Approval Process Control
  • Archiving & Retention
  • Assessment Management
  • Asset Tracking
  • Attestation
  • Audit Management
  • Audit Performance
  • Audit Planning
  • Audit Trail
  • Automated Scheduling
  • Bills of Material
  • Business Process Control
  • Calibration Management
  • Change Management
  • Collaboration Tools
  • Commenting/Notes
  • Communications Management
  • Complaint Management
  • Compliance
  • Compliance Management
  • Compliance Tracking
  • Configurable Workflow
  • Consent Management
  • Content Management
  • Corrective and Preventive Actions (CAPA)
  • Cross-system Integration
  • Customer Complaint Tracking
  • Customizable Forms
  • Customizable Reports
  • Customizable Templates
  • Dashboard
  • Dashboard Creation
  • Data Governance
  • Data Import/Export
  • Data Security
  • Data Storage Management
  • Data Synchronization
  • Data Visualization
  • Defect Tracking
  • Design Management
  • Digital Signature
  • Document Automation
  • Document Capture
  • Document Check-in/Check-out
  • Document Classification
  • Document Coding & Control
  • Document Control
  • Document Generation
  • Document Lifecycle Management
  • Document Management
  • Document Review
  • Document Storage
  • Document Templates
  • Documentation Management
  • EDI
  • Electronic Signature
  • Email Alerts
  • Enterprise Risk Management
  • Equipment Management
  • Event Logs
  • Evidence Management
  • Exceptions Management
  • Execution
  • FDA Compliance
  • File Management
  • File Sharing
  • For Engineering Documents
  • For Healthcare
  • Forms Management
  • Full Text Search
  • Generative AI
  • Governance
  • HIPAA Compliant
  • ISO Compliance
  • ISO Standards Management
  • IT Risk Management
  • Incident Management
  • Inspection Management
  • Internal Controls Management
  • Inventory Management
  • Issue Management
  • Issue Tracking
  • Log Management
  • MES
  • Machine and equipment
  • Maintenance
  • Maintenance Management
  • Maintenance Scheduling
  • Manufacturing Software
  • Mobile Access
  • Monitoring
  • Multi-Language
  • Multi-Location
  • Multiple Format Support
  • Nonconformance Tracking
  • Onboarding
  • Operational Risk Management
  • Order Management
  • PCI Assessment
  • PCI Compliance
  • Performance Analysis
  • Performance Metrics
  • Policy Creation
  • Policy Library
  • Policy Management
  • Policy Training
  • Predictive Analytics
  • Prioritization
  • Product Data Management
  • Production Scheduling
  • Project Management
  • Quality Assurance
  • Quality Control
  • Quality Management
  • Real-Time Analytics
  • Real-Time Data
  • Real-Time Monitoring
  • Real-Time Notifications
  • Real-Time Reporting
  • Real-Time Updates
  • Remediation Management
  • Reminders
  • Reporting & Statistics
  • Reporting/Analytics
  • Response Management
  • Revision History
  • Risk Alerts
  • Risk Analysis
  • Risk Assessment
  • Risk Management
  • Risk Methodology
  • Risk Reporting
  • Risk Scoring
  • Role-Based Permissions
  • Root Cause Analysis
  • Routing
  • Rules-Based Workflow
  • Safety Management
  • Scheduling
  • Search/Filter
  • Secure Data Storage
  • Security Auditing
  • Self Service Portal
  • Sensitive Data Identification
  • Single Sign On
  • Status Tracking
  • Supplier Management
  • Supplier Quality Control
  • Surveys & Feedback
  • Task Management
  • Template Management
  • Third-Party Integrations
  • Traceability
  • Training Management
  • Trend Analysis
  • User Management
  • Vendor Management
  • Version Comparison
  • Version Control
  • Version Rollback
  • Vulnerability Scanning
  • Workflow Management

Integrations

  • Total integrations12
  • 1Password
  • 360Learning
  • ADP Workforce Now
  • Arena
  • Asana
  • BambooHR
  • Bitbucket
  • Certn
  • Checkr
  • ClickUp
  • ComplianceWire
  • Datadog
  • DigitalOcean
  • Elium
  • Freshservice
  • GitHub
  • Google Cloud Storage
  • Google Workspace
  • Gusto
  • Heroku
  • Iru
  • Jamf Pro
  • Jira
  • Justworks
  • Microsoft 365
  • Microsoft Azure
  • Microsoft SQL Server
  • MongoDB
  • Namely
  • NetSuite
  • Netlify
  • NinjaOne
  • NordPass Business
  • Notion
  • Officient
  • Okta
  • OneLogin
  • PayCaptain
  • Paychex
  • Paycom
  • Paycor
  • Paylocity
  • Payworks
  • Personio
  • Pivotal Tracker
  • Priority Matrix
  • Probely
  • QuickBooks Payroll
  • Ramp
  • Re:amaze
  • Retool
  • Rippling
  • Rollbar
  • SAP BTP
  • SAP SuccessFactors HCM
  • SafeStack
  • ServiceNow
  • Shopify
  • Shortcut
  • SimpleMDM
  • Slack
  • SmartFile
  • Snowflake
  • Snyk
  • Square Payroll
  • Tableau
  • Trello
  • TriNet HR Plus
  • TriNet PEO
  • Tribeloo
  • Twingate
  • UKG Pro
  • VMware Workspace ONE UEM
  • Vendr
  • Vonage Business Communications
  • Webex Suite
  • Whimsical
  • Wiz
  • Workable
  • Workday HCM
  • Workday Peakon Employee Voice
  • Wrike
  • Xero
  • YouTrack
  • Zapier
  • Zavanta
  • Zendesk Suite
  • Zinc
  • Zoho BugTracker
  • Zoho Desk
  • Zoho People
  • myPolicies
  • timetoreply
  • Total integrations86
  • 1Password
  • 360Learning
  • ADP Workforce Now
  • Arena
  • Asana
  • BambooHR
  • Bitbucket
  • Certn
  • Checkr
  • ClickUp
  • ComplianceWire
  • Datadog
  • DigitalOcean
  • Elium
  • Freshservice
  • GitHub
  • Google Cloud Storage
  • Google Workspace
  • Gusto
  • Heroku
  • Iru
  • Jamf Pro
  • Jira
  • Justworks
  • Microsoft 365
  • Microsoft Azure
  • Microsoft SQL Server
  • MongoDB
  • Namely
  • NetSuite
  • Netlify
  • NinjaOne
  • NordPass Business
  • Notion
  • Officient
  • Okta
  • OneLogin
  • PayCaptain
  • Paychex
  • Paycom
  • Paycor
  • Paylocity
  • Payworks
  • Personio
  • Pivotal Tracker
  • Priority Matrix
  • Probely
  • QuickBooks Payroll
  • Ramp
  • Re:amaze
  • Retool
  • Rippling
  • Rollbar
  • SAP BTP
  • SAP SuccessFactors HCM
  • SafeStack
  • ServiceNow
  • Shopify
  • Shortcut
  • SimpleMDM
  • Slack
  • SmartFile
  • Snowflake
  • Snyk
  • Square Payroll
  • Tableau
  • Trello
  • TriNet HR Plus
  • TriNet PEO
  • Tribeloo
  • Twingate
  • UKG Pro
  • VMware Workspace ONE UEM
  • Vendr
  • Vonage Business Communications
  • Webex Suite
  • Whimsical
  • Wiz
  • Workable
  • Workday HCM
  • Workday Peakon Employee Voice
  • Wrike
  • Xero
  • YouTrack
  • Zapier
  • Zavanta
  • Zendesk Suite
  • Zinc
  • Zoho BugTracker
  • Zoho Desk
  • Zoho People
  • myPolicies
  • timetoreply