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Top Rated Encryption Software with Hipaa compliance - Page 2

Last updated: May 2026

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47 software options

DriveLock logo

Cloud-based tool for protecting company data & end-devices

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DriveLock is a cloud-based software that helps with encryption of all information and protection against unauthorized access.

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JumpCloud Directory Platform logo

A cloud directory platform for secure access to resources

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Two-way TLS authentication and encryption to third-party assessments and independent audits (e.g. Type 1 SOC)

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Files.com logo

Secure File Orchestration for a Cloud World

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Files.com is a cloud-native MFT and file orchestration platform for secure file transfer, storage, automation, and compliance — with deep integrations across cloud providers, protocols, and enterprise workflows.

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Syxsense logo

Unified Security and Endpoint Management

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Syxsense is a leading USEM solution designed to help SecOps departments, MSPs, and IT professionals in organizations with 100-100,000 endpoints manage and secure their environment.

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ConnectWise SIEM logo

Threat detection and response management software

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ConnectWise SIEM is a threat detection and response management software designed to help enterprises create, launch, and manage cybersecurity programs. The platform enables organizations to identify potential threats and malicious activities across networks & connected devices via a unified portal.

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x360Cloud logo

Back up for Microsoft 365

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Designed for business use, Axcient x360Cloud - formerly CloudFinder - provides automatic, reliable and secure backup of Microsoft 365.

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WebTitan logo

DNS-based web filter, malware/phishing protection & security

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DNS Based Web Security Layer

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Hushmail logo

Email, web form, and e-signature solution for healthcare

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Hushmail is a web-based email, web form, and e-signature service that enables businesses to send and receive encrypted client communications. The drag-and-drop form builder, template directory, and integrated e-signatures are perfect for healthcare, legal, and other fields requiring confidentiality.

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Proton VPN logo

VPN with DNS filter function and Secure Core architecture.

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Lock down sensitive data with Proton VPN. Everything is safe with unbreakable encryption — no leaks, no logs, no complexity.

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Proton Mail logo

Web-based email management platform

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ProtonMail is a web-based email management platform that helps businesses securely transmit encrypted emails between users both inside and outside of the organisation.

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Progress ShareFile logo

Secure file sharing and sync

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Progress ShareFile provides users with the ability to send, receive and share large business files securely. Through the ShareFile portal, offer clients a personalized, company-branded and password-protected platform from which to collaborate on files.

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Confidencial logo
(0)

Cloud-based data protection and security solution

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Confidencial is a document security solution that enables users to protect sensitive data with granular encryption controls.

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Xecrets Ez logo
(0)

Encryption software for macOS, Linux, and Windows

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Xecrets Ez is a free, cross-platform desktop app for Windows, macOS, and Linux. It offers AES-256 file encryption, a simple UI, and secure deletion of originals. Works fully offline, with optional premium features like YubiKey support and Shamir’s Secret Sharing.

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LAN Crypt File and Folder Encryption logo
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Designed for businesses of all sizes and all in industries.

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u.trust LAN Crypt protects your confidential files against unauthorized external or internal access.

Furthermore, u.trust LAN Crypt uses a strict role split approach: The network administrator can access and
manage files and the security officer manages keys and security policies.

Read more about LAN Crypt File and Folder Encryption

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TeraCryption logo
(0)

Tool that offers file security for HIPAA and CMMC compliance

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TeraCryption is a file encryption management system that helps businesses protect sensitive files and control access to information to achieve HIPAA and CMMC compliance.

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MeSign logo
(0)

End-to-End encryption and digital signature app for emails.

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Provides email encryption, digital signing and timestamping service for your corporate emails.

Auto-configure email certificates, encrypt email message automatically by default with S/MIME standard.

Cloud and on-premise key management are both supported.

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Proton Drive logo
(0)

Encrypted cloud storage and collaboration tools for teams

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Keep your business data truly private with Proton Drive's zero-access, end-to-end encryption across all files, documents, and spreadsheets. Built on open-source, independently audited code and ISO 27001 certified.

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Cornerstone MFT Server logo
(0)

Network security and managed file transfer solution

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Cornerstone MFT is a cloud-based solution, which assists enterprises, financial services and healthcare organizations with managing security and file transfers across servers. Key features include process automation, compliance management, collaboration, and data encryption.

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strongDM logo
(0)

strongDM is the Infrastructure Access Platform.

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strongDM’s infrastructure access platform gives businesses confidence in their access and audit controls at scale. It combines authentication, authorization, networking, and observability in simplifying workflows and making it easier for technical staff to access the tools they need.

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ANKASecure logo
(0)

Quantum-safe encryption for enterprise data

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ANKASecure is encryption software protecting enterprise data from quantum threats using certified post-quantum algorithms. It offers quantum-resilient encryption with NIST certification, flexible deployment via CLI, API, and SaaS, and supports migration from RSA and ECC. Features include cryptographic sovereignty with full key control, crypto-agility for adaptable algorithms, and centralized key management.

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Basis Theory logo
(0)

A compliant platform to secure, use, and manage your data

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A compliant and developer-friendly platform to secure, use, and manage the data that matters most to you.

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TDAccess logo
(0)

Encryption software

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Latest cross-platform compression and transmission capabilities that meets (FIPS) 140-2 requirements.

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