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Top Rated e-Prescribing Software with Free trial

Last updated: September 2026

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23 software options

MDToolbox-Rx logo

Surescripts & EPCS certified e-prescribing system

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MDToolbox e-Prescribing is a Surescripts & EPCS certified e-Prescribing software which can be used standalone on desktops, tablets, or phones, or integrated

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Tebra logo

Automated solution for medical practice management

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Tebra helps medical providers optimize clinical processes by handling administrative tasks so that doctors can focus on patient care

Tebra is popular with physician practices with 1-10 providers and medical billing companies with 1-100 providers.

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CarePaths EHR logo

E-Health Records & Practice Management System w/ Telehealth

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ONC-Certified & HIPAA compliant cloud-based EHR and practice management platform with telehealth. Accept e-referrals, FREE claim submissions, online payments, E-statements, online scheduling, appointment reminders, clinical documentation, customizable forms, secure messaging, outcomes monitoring.

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OrderConnect logo
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E-prescribing software with real-time interaction checking

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OrderConnect is a web-based electronic prescribing software designed to help businesses in the healthcare industry view the current medication profile of patients with primary diagnoses and known allergies. The platform lets teams pull up patients' complete medical history using devices across multiple locations.

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TherapyNotes, LLC logo

Online mental health EMR and practice management software.

Web-based practice management & electronic health records (EHR) software for behavioral health with thousands of active users, and unlimited customer support.

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DocVilla logo

Medical Practice Management Software

DocVilla: transform your independent medical practice with a comprehensive suite of Cloud-Based EMR and EHR software, telemedicine, e-prescribing, lab integration, Fullscript, analytics, POS, Patient portal, and inventory management. Secure, efficient, and hosted on Google Cloud and AWS.

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OptiMantra logo

EMR and practice management solution

OptiMantra is a practice management and EMR solution specifically created for integrative and wellness practices.

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My Best Practice logo

Software for managing healthcare operations and records

My Best Practice, the EHR for evidence-based clinicians, simplifies creating and maintaining client accounts, scheduling appointments, managing client information, billing, and more.

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75health logo

Cloud-based EMR / EHR for doctors, clinics & hospitals

75health platform is easy to use and helps doctors, clinics, and hospitals to stay up-to-date. Streamlining the process to cloud-based software gives them more time and energy.

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iClinic logo

Medical practice management solution with EMR

iClinic is a medical practice management solution that is available in Portuguese and offered in Brazil. The platform is designed to help businesses with teleconsultation, online marketing, calendar management, and electronic medical records.

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Nexus EHR logo

Modern, Certified EHR with Native AI & Rapid Rx

Secure medication management with Rapid Rx. Import 2 years of Surescripts history instantly. Features fully compliant EPCS/PDMP integration, automated pharmacy search, and smart "favorites" lists for rapid-fire prescribing with real-time safety alerts.

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Intergy logo

Enterprise EHR & practice management with mobile app support

Greenway’s electronic health record (EHR) and practice management platform Intergy offers a user-friendly, specialty-focused solution for ambulatory healthcare practices. It provides tools to manage chronic conditions, capture payer incentives, and thrive in the world of value-based healthcare.

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H2H DigitalRx logo

by H2H Solutions

H2H Digital Rx is a surescript-certified HIPAA-compliant cloud-based e-prescribing solution that helps healthcare professionals manage patient medication history, formulary, and refills. Features include EPCS, PDMP, RTPB, EPA, favorite Drugs, prescription templates, and many more.

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Enablemypractice logo

Cloud-based EHR solution for medical professionals.

Enablemypractice is an EHR (electronic health record) solution, which helps small to large healthcare organizations manage patient engagement, online billing, appointment schedules, medicine databases, and more. The platform provides several features such as communication tools, visit management, artificial intelligence (AI), reporting, electronic prescriptions, chronic care management (CCM), custom templates, live chat, mobile application, and bed management.

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Genamet logo

All-in-one clinic management software in the cloud

Genamet is a comprehensive Clinic Management Software that enables users to streamline their processes by digitizing their workflow, thereby improving accessibility and efficiency.

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MNprogram logo

Sales management software for legal and medical industries

MNprogram is a cloud-based system designed to help businesses in legal, medical, healthcare, and other industries manage sales, customers, billing, accounting, and more. It enables supervisors to automate employee scheduling, run marketing campaigns, and store documents in a centralized repository.

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Insta logo

Hospital management system for healthcare operations

Insta is a cloud-based hospital management software that offers tools for digitizing and automating workflows, streamlining operations, enhancing patient engagement, and managing patient health records. The platform can be used by speciality clinics, medical centers, day care centers, and hospitals.

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athenaOne logo

AI healthcare software for medical practices

AthenaOne is a fully-integrated healthcare solution combining electronic health records, medical billing, practice management, and patient engagement. The AI-native platform streamlines clinical documentation, automates data exchange, and simplifies administrative tasks for providers. With features like customizable workflows, automated wellness outreach, and telehealth, the system helps medical practices enhance clinical outcomes and operational efficiency.

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Practice Fusion logo

Cloud-based electronic health record platform

Practice Fusion is a cloud-based electronic health record management solution offering features such as e-prescription, charting, scheduling and lab integration

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ClinBase logo
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EMR with an AI scribe for physicians in Mexico

Cloud EMR for independent physicians in Mexico: charts and visit notes, prescriptions as signed PDFs with a QR code, scheduling with online booking and reminders, video visits, and an AI scribe that drafts the note from the recorded visit. Free plan, paid plans from $149 MXN per month.

Read more about ClinBase

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Doctor108 logo
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Medical practice management software

Doctor108 is a Windows-based medical practice management software that helps doctors manage their clinics and hospitals. This software is designed to streamline administrative and managerial processes, making it a beneficial tool for doctors.

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Docline 360 logo
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Telemedicine platform

Docline is a comprehensive telemedicine platform offering video consultations, an e-prescription network, AI symptom checker, and patient management tools. It enables diagnosis, treatment, and remote decision-making with virtual visits, e-prescriptions, and appointment scheduling. The secure platform enhances healthcare efficiency, boosts provider productivity, and fosters digital health transformation for businesses, hospitals, and health professionals.

Read more about Docline 360

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Convenient Care logo
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Multi-specialty hospital management software

Convenient Care is a white-labeled hospital management application designed for multi-speciality hospitals that bridge disparate patient data (lab, pharmacy, and EMR) and gives a paradigm shift in standard and quality of care.

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