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Top Rated Data Loss Prevention Software with Hipaa compliance

Last updated: May 2026

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49 software options

Netwrix Endpoint Protector logo

Data loss prevention and endpoint protection tool

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Netwrix Endpoint Protector is a data loss prevention tool which assists businesses of all sizes with data encryption and file scanning. Key features of the platform include compliance management and reporting, policy management, device control, and sensitive data identification.

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Teramind logo

Employee Monitoring, UAM, ITM & IRM, DLP, and Compliance.

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Teramind is a unified employee monitoring, insider threat detection, data loss prevention, compliance and governance solution. Track digital interactions, optimize productivity, monitor privileged users, to enforce policies, prevent IP and data leaks and maintain and prove regulatory compliance.

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Backblaze B2 Cloud Storage logo

Always-hot cloud storage to store, manage, and protect data

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A leading specialized cloud provider that makes it easy for businesses to store, use, and protect their data. Over 100K customers in 175 countries use B2 Cloud Storage to host content, build & run applications, manage media, back up & archive data, and protect and recover from ransomware attacks.

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GoodAccess logo

Zero Trust Architecture as a Service

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Cybersecurity platform (SASE/SSE) that enables easy Zero Trust Architecture implementation for medium enterprises, any scale.

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NeoCertified logo

Secure email for confidential & sensitive documents

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NeoCertified provides secure email encryption with Outlook integration for businesses of all industries, including healthcare, finance, legal & education

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Cypherdog Encryption logo

One click. Complete protection.

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Cypherdog Encryption (CE) provides the ability to encrypt and decrypt e-mails with attachments with confirmation of the identity of the parties to the communication.

No "trusted" third party, zero-knowledge security model, asymmetric encryption.

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Keepit logo

Protecting Cloud Data is Your Responsibility

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Keepit is a software company specialized in Cloud-to-Cloud data backup and recovery.

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Comet Backup logo

Deliver Fast, Secure Data Protection

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Fast, secure data loss prevention software for businesses and IT providers.

Comet is a flexible, all-in-one backup platform available in 13 languages. You choose your backup environment and storage destinations.

Simple, profitable pricing. No contracts. 30-day FREE trial!

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NinjaOne logo

Unified endpoint management & IT automation platform

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The NinjaOne Unified IT Operations Platform delivers endpoint management, autonomous patching, backup, and remote access in a single console to improve efficiency, increase resilience, and reduce spend.

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DriveStrike logo

Data and device protection for businesses of all sizes

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DriveStrike is a cloud-based data and device protection solution which helps businesses of all sizes with data security and compliance. Key features include incident management, policy management, automated device recognition, real time monitoring, and remote locking.

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Malwarebytes for Business logo

Complete cybersecurity software for businesses

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Malwarebytes is a network security software that enables businesses to identify and detect potential cyberthreats across networks or enterprise servers. The cloud-based Malwarebytes Nebula platform lets administrators gain visibility into threat patterns from the centralized dashboard.

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Clumio logo

Data Protection Built for the Cloud

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Built to help simplify data protection on AWS, Clumio's secure isolated backup service enables organizations to meet strict compliance requirements, put a gap between data and bad actors, backup and restore data in minutes, and optimize cloud storage.

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Safetica logo

Intelligent Data Security

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Safetica protects your sensitive data against insider threats, and breaches by detecting security incidents.

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OpenText Cloudally Backup for Microsoft 365 logo

Never Face Data Loss Again!

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Enterprise-grade automated backup and recovery solution, since 2011. Backup all your business critical data, Protect your business-critical cloud data with CloudAlly. 

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Google Cloud logo

Modular platform for computing, hosting, storage and more

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Google Cloud Platform is a modular-based platform providing multiple build and scale services to businesses of any size within any industry. It offers tools for document storage, data warehousing, security key enforcement, app creation, API management, AI and machine learning, live chat, and more.

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EDpCloud logo

Real-Time Cross-Platform Replication and Synchronisation.

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Real-time cross-platform file replication, data distribution, and file synchronization between different operating systems, different cloud providers, and different geographic sites.

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Kitecyber logo

AI endpoint security for streamlined protection

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Kitecyber is an AI-enabled, endpoint-based security and compliance solution that protects users, SaaS apps, and sensitive data. It prevents phishing attacks, manages SaaS supply chain risks, and secures internet and SaaS access. Kitecyber offers user identity protection, data protection, and compliance capabilities, all in a unified solution that can be deployed without the need for cloud gateways or local appliances.

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ManageEngine AD360 logo

Identity and access management platform

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ManageEngine AD360 is an enterprise IAM software solution that helps businesses of all sizes manage identities securely and ensure compliance. Key functionalities include automated identity lifecycle management, secure single sign-on, adaptive multi-factor authentication, approval-based workflows.

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Exabeam New-Scale Fusion logo

Real Intelligence. Real Security. Real Fast.

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A scalable, cloud-native architecture provides rapid data ingestion, hyper-fast query performance, powerful behavioral analytics & AI.

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OneVault logo

The Most Secure Solution for Archiving, Governance & DLP

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Donoma OneVault delivers multi-data archiving of email and communication records for centralized, streamlined archiving.

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Beyond DLP logo

Product Data Protection Beyond Boundaries

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Beyond DLP is a data protection platform to track and protect scattered data. ITsMine's software brings data protection to enterprises in a clear API-based solution.

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SendGuard for Outlook logo

Governance, Risk & Compliance Solution for Outbound Emails

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SendGuard for Outlook prevents accidental data loss caused by misdirected emails and mis-attached files.

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Nightfall AI logo

Data loss prevention tool with deep learning capabilities

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Nightfall DLP is a cloud-based data loss prevention software designed to help businesses discover, manage, classify, and protect sensitive data using machine learning technology.

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Secure Remote Worker logo

Secure Endpoints for Remote & In-Office Environments

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Secure Remote Worker addresses the challenges faced by BPOs & Contact Centers enabling them to create a secure and compliant remote working environment that allows them to scale faster.

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SysCloud logo

Start making smarter cloud backups

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SysCloud is a BaaS provider offering automated backups, restores & unlimited retention for critical SaaS apps in a single pane of glass.

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