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Document Control Software with Digital Signature (2026) - Page 2

Last updated: April 2026

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65 software options

SimplerQMS logo

Cloud-based quality management software for life sciences.

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Expert-driven, fully validated eQMS for Life Science companies to streamline quality processes, ensure compliance, and stay audit-ready.

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Avokaado logo

Contract intelligence platform for legal, revenue, and ops.

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Avokaado is an all-in-one contract lifecycle management platform that helps teams manage their documents without ever leaving the platform enabled by: clause-based contract automation, drafting based on smart templates, workflow management with digital signing and electronic storing.

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ACE logo

Enterprise Quality Management System

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Adaptive Compliance Engine (ACE) is a cloud-based quality management system designed to help businesses in biotechnology, cosmetics, pharmaceuticals, healthcare, manufacturing, and other industries manage compliance, quality, and efficiency across all operations in real-time.

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Singlepoint logo

Cloud-based QMS and workflow management software

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Singlepoint is a cloud-based QMS and workflow management software that helps businesses automate and streamline internal audit programs, handle official documents, and track projects across teams. The tool allows users to capture, triage, resolve and analyze multiple workplace incidents.

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Orcanos logo

Compliance for Design Control, Risk and Quality Management

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21 CFR Part 11 Compliant e-DMS

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Digital Integrated Management System logo

Quality, compliance, governance, improvement & digitization

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Digital Integrated Management System is an AI-powered IMS that connects QMS, DMS, BPM, and GRC to standardize processes, strengthen compliance, and surface real-time insights. Purpose-built for regulated sectors and certified to ISO 27001 with CSV validation, it ensures full traceability and audit readiness.

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altaFlow logo

No-Code Workflow Automation Platform

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AirSlate is a no-code business automation platform that can configure and automate any business process. The platform allows users to create and automate complex workflows using robotic process automation (RPA), document process automation (DPA) and a drag-and-drop flow creator.

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ViewCenter logo

Document management platform

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A secure digital environment where your business-critical documents live, and your important processes can be optimized & automated to achieve a strong Return on Investment.

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dMACQ DMS+ logo

Document management system for legal, HR & finance teams

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dMACQ DMS+ offers robust document control features, including AI-driven auto-indexing, dynamic metadata and seamless integration with third-party apps. Designed for high compliance needs, it ensures secure storage, version control and access management.

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Nintex DocGen for Salesforce logo

Document automation for Salesforce (formerly Drawloop)

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DocGen - formerly Drawloop - is a document generation software designed to automate document processes in Salesforce with Dynamic Document Packages (DDP).

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QISS Quality Management System logo

Cloud-based Quality Management Software

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QISS QMS is software for quality management systems. It is designed to streamline your organization’s processes and support compliance.

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Sierra QMS logo

Automate Regulatory Compliance and Speed Your Innovations!

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Sierra QMS allows you to publish information from your QMS into templatized documents to share with regulatory bodies. Generate validation artifacts directly from source data in application lifecycle projects. Transition published documents through approval workflows using Sierra QMS.

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Read & Sign logo

Document management and digital signature tracking tool

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read&sign is a digital signature solution, providing essential features, such as policy acknowledgment tracking, automated reminders, and secure document handling. read&sign ensures compliant engagement with critical documents.

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ZenQMS logo

Quality and compliance management solution for businesses

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ZenQMS is a cloud-based solution that assists businesses with quality management, employee training, and regulatory compliance. Key features include document management, change control, issue tracking, auditing, data export, notifications, and reporting.

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isoTracker Document Management logo

Web-based document storage & workflow automation for SMBs

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isoTracker Document Management Software provides automated version and document control for regulatory compliance. This cloud-based system features approval workflows, task notifications, and document archiving while ensuring proper review and restricted access. It offers secure storage with encryption, daily backups, and activity tracking for organizations complying with ISO standards and FDA requirements.

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Assai logo

Document management tool for handling assets and projects

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Assai offers a DMS, allowing complex projects and operations to be managed from a document perspective. We provide document control, document management, and asset information management to industries such as oil and gas, renewable energy, construction and engineering, and others.

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Trackmedium eQMS logo

Cloud-based Quality Management System (eQMS)

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Trackmedium eQMS is a cloud-based platform designed to help businesses of all sizes automate document control and regulatory compliance processes for various industry standards and global regulations, including ISO 9001, ISO 14001, IATF 16949, and OSHA.

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Agatha Applications logo

Solution for clinical and quality operations

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Agatha provides a suite of applications for biotech, pharmaceutical, and medical device companies to manage their processes. Agatha applications include Solution Manager, Formulary Management, Quality Control Reporting, Clinical Research Management and Regulatory Compliance.

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Melento logo

Productivity Expert For Every Business

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SignDesk is a global provider of document & workflow automation solutions to help businesses achieve digital transformation goals & optimize productivity. Our award-winning & globally compliant solutions automate digital onboarding, document execution, contract management, and recurring payments.

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Docusoft CloudFiler logo

Cloud-based document and collaboration management software

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Docusoft CloudFiler is built with businesses at the fourth front of its mind. The system is made with key applications to help businesses save, amend, and collaborate on documents internally and with their outbound contacts.

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Contentverse logo

Simple, secure document management for everyone

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Contentverse is a secure, versatile, fully-featured enterprise content management solution. 128-bit encryption. DocuSign integration. On-premise and/or cloud implementation. With a robust indexing module that can detect text, barcodes, and QR codes on scanned pages as searchable metadata.

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netLex logo

Simple and secure agreements

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netLex is an end-to-end platform used by leading companies to manage their contracts’ lifecycle. Gain +240% productivity by automating document creation and configuring intelligent workflows, as well as extracting data for management and intelligence panels.

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Matrix Requirements logo

Spend your time building Medical Devices, not on paperwork!

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Matrix Requirements allows you to build documents of building blocks, like audit trails, signatures boxes etc. They are connected to the project and can have sections which are automatically populated with the latest project data. Each controlled document can be frozen at any time.

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SYDLE ONE logo

BPMS, ECM, CRM & Service Desk- All-in-one platform

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In a single platform, it combines the tools to customize document approval flows, have full versioning control, search within document content, learn physical file storage location, ensure authenticity with digital signatures, and more.

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Bounsel Flow logo

Create documents in minutes with Bounsel Flow

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The all-in-one CLM software powered by artificial intelligence.

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