Pearl - 2026 Pricing, Features, Reviews & Alternatives

Pearl brings FDA-cleared artificial intelligence to everyday dentistry, helping practices catch more disease, present cases with confidence, and run more efficiently. Pearl is the only dental AI company cleared to read both 2D and 3D imaging, with detection spanning more than 100 conditions — giving clinicians a consistent, objective second set of eyes on every radiograph.

At the core is Second Opinion, which analyzes x-rays chairside and instantly highlights findings like caries, calculus, periapical radiolucencies, and bone loss. The result is earlier detection, more standardized diagnoses across every provider in the practice, and clearer case presentation that patients trust and accept.

Pearl extends well beyond the operatory into the full business of running a practice. Practice Intelligence layers clinical AI onto day-to-day operations — flagging untreated disease across the patient base, strengthening recall, and turning diagnostic data into actionable opportunities for the front office and treatment coordinators. Pearl RCM combines insurance verification, claim evidence quality control and clean claim optimization to facilitate efficient and predictable revenue cycle management — reducing claim friction and helping practices get paid faster, working on behalf of the practice rather than the carrier.

Pearl Voice adds AI-powered ambient listening to enable hands-free clinical note create and perio charting. Transforming patient conversations and exams into complete, reliable, legally compliant documentation, Pearl Voice enables more accurate and complete patient records and insurance claims, while reducing manual work and enabling dental teams to stay focused on patients.

Whether a practice is adopting AI for the first time or looking to extend the value of tools it already uses, Pearl is built to scale — from the solo practitioner to the largest DSO. With clearances and CE marking trusted by practices across the U.S., U.K., and over 120 more countries worldwide, Pearl is the AI platform purpose-built for modern dentistry.