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Clinical Trial Management Software with Randomization (2026)

Last updated: March 2026

Key features of Clinical Trial Management Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • 21 CFR Part 11 Compliance: Reviewers emphasize the importance of 21 CFR Part 11 compliance for secure, trustworthy electronic records and signatures, ensuring regulatory adherence. 99% of reviewers rated this feature as important or highly important.
  • HIPAA Compliant: Users value HIPAA compliance for safeguarding patient privacy and maintaining ethical standards in clinical research. 96% of reviewers rated this feature as important or highly important.
  • Audit Trail: An effective audit trail feature helps users track changes, ensuring transparency and compliance during audits. 96% of reviewers rated this feature as important or highly important.
  • Electronic Data Capture: Reviewers appreciate real-time data capture, reducing errors and improving efficiency in clinical trials. 94% of reviewers rated this feature as important or highly important.
  • Document Management: Users highlight the ease of organizing, uploading, and retrieving documents, which streamlines regulatory inspections and daily operations. 94% of reviewers rated this feature as important or highly important.
  • Clinical Study Management: Reviewers find it essential for tracking study progress, managing sites, and ensuring data integrity throughout clinical trials. 92% of reviewers rated this feature as important or highly important.
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46 software options

Castor EDC logo

The top-rated EDC system in the world *EDC + ePRO + eConsent

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The only GCP & 21 CFR compliant system that's affordable for every researcher and has all the features of expensive systems. Start now.

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RealTime-CTMS logo

Cloud-based clinical trial management system

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RealTime-CTMS is an end-to-end clinical trial management system designed to streamline clinical study information and company processes

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Viedoc logo

Electronic data capture for clinical trials

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Viedoc delivers powerful eClinical solutions that streamline clinical trials, making data collection, management, and analysis faster and easier. Trusted in 75+ countries, powering 7,000+ studies with more than 1.6M+ participants.

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Researchmanager – Clinical Research Suite logo

EDC, CTMS, eTMF, ePRO, RTSM, eConsent, RIMS, LIMS

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The Clinical Research Suite is an online platform tailored for managing clinical trials, facilitating organizations in planning, strategizing, and executing life science research. It empowers researchers to collect and analyze data in standardized formats, optimizing scientific research and decisio

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ShareCRF logo

EDC software for clinical research

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Take control of your clinical trial data with ShareCRF. Configure your study in hours—no coding or external help needed. Enjoy an intuitive interface, full regulatory compliance, and unmatched adaptability to fit your unique study needs. Simplicity, efficiency, and reliability in one platform.

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Medrio logo

Powering your research potential.

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Medrio is an electronic data capture (EDC) tool for clinical research teams with tools for capturing, storing, analyzing, & managing patient data during clinical trials. Medrio offers secure storage of patient data, automates regulatory compliance management & allows users to build custom studies.

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Ripple logo

Patient recruitment and management for clinical trails

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Ripple is a SaaS platform that automates patient recruitment, administrative tasks, and reporting activities for contract research organizations and academic centers that are conducting clinical research and trials, as well as translational and social studies.

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OpenClinica logo

Driving the future of clinical trials. Better data, faster.

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OpenClinica is a compliant, all-in-one clinical data management platform offering electronic data capture with collaborative drag and drop interface for designing studies, randomization and supply management, patient reported outcomes (ePRO & eCOA), plus reporting tools with chart visualizations

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TrialKit logo

Unified eClinical platform with embedded intelligence

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TrialKit is a global, cloud-based development platform for end-to-end, "direct-from-source" data collection and workflow management across all phases of clinical trials.

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ClinCapture logo

Clinical trial platform for research teams

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Captivate is a clinical trial management platform that offers multiple integrated modules for conducting research studies. The software includes electronic data capture, electronic patient-reported outcomes, electronic consent, randomization and trial supply management, electronic trial master file, and medical coding capabilities. Captivate is designed to support organizations involved in clinical research operations.

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Clinical Conductor CTMS logo

Comprehensive Hybrid Clinical Trial Managment System (CTMS)

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Clinical Conductor CTMS (CC CTMS) is the most used by research sites worldwide. Part of the CCTrialSuite, CC CTMS is helping leading hospitals and health systems of every size or complexity to maximize their decentralized trial results. Optimize recruiting, enrollment, finances, reporting and more.

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Health Cloud logo

Patient relationship management software in the cloud

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Salesforce Health Cloud is a collaborative, all-round healthcare CRM and patient management software for healthcare providers, payers, and patients

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Prelude EDC logo

Clinical trial management system for researchers

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Prelude EDC is a web-based EDC solution that helps researchers and clinicians with clinical trial management. Key features include electronic data capture, data management, project management, custom fields, audit trail, automatic notifications, and compliance management.

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Datacapt logo

One unified Platform. Datacapt is reimagining your Trials.

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Datacapt is an intuitive and easy-to-use EDC platform with eCRF, ePRO, eConsult, and eConsent. Access real-rime reports, high-quality data capture, and fully compliant.

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Climedo  logo

Powerful, modular and secure solutions for DCTs.

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Climedo is a secure and modular cloud-based electronic data capture (EDC) tool for decentralized clinical trials. It enables the clinical validation and post-market surveillance of of medtech and pharma products using tools such as cOA/ePRO, eCRF, clinical study tracking, input forms, etc.

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Jeeva eClinical Cloud logo

Streamline and automate clinical trials with software and AI

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Jeeva eClinical cloud helps clinical researchers, CROs, and Biopharma sponsors to accelerate the clinical trial process from patient screening and enrollment, clinical data capture, protocol scheduling, patient adherence, and retention with user-friendly software, integrations, and Agentic AI.

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AQ Platform logo

Clinical trial management software

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AQ is a clinical trial management solution integrating multiple modules for study management, operations, recruitment, electronic investigator site file (eISF) and patient source file (PSF), and reporting. It offers real-time analytics to gain visibility into data-driven insights for optimized trial accuracy.

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Medicai logo

AI-Powered Medical Imaging Infrastructure & Healthcare APIs

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Manage imaging in clinical research with centralized access, standardized reporting, audit trails, and secure cross-site collaboration. Streamlines investigator review and sponsor communication.

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Flex Databases platform logo

Unified platform for handling clinical trials and documents

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One system for clinical development process and beyond. Scalable and flexible CTMS with all the features you may need. Cloud based and on-premises options. Validated and complaint with regulations.

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CRFweb logo

Electronic data capture software for clinical trials

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CRFWEB is an electronic data capture (EDC) software that helps organizations collect, manage, and analyze clinical data in compliance with FDA guidelines. With the eCRF module, staff members can handle queries, formulas, audit logs, edit checks, and more from within a centralized dashboard.

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StudyPal logo

Cloud-based clinical trial software

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StudyPal is a cloud-based clinical trial software that offers features such as multilingual support, wearable technology, eConsent, gamification, patient-reported outcomes, and automated engagement solutions.

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Dacima Clinical Suite logo

Electronic data capture solution

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Dacima's Clinical Suite ePCTR is meticulously crafted to deliver unmatched quality in electronic data capture for clinical trials.

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MainEDC logo

EDC, IWRS, Drug Supply, Logistic and ePRO Cloud Platform

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Cloud-based EDC, IWRS, Drug Supply, Logistic, ePRO, Registries, PharmMarketing, eConsent, eCOA, eSource easy-to-use and powerful integrated platform.

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DFdiscover logo

Clinical data management system for research organizations

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DFdiscover is a clinical data management system which helps academic and non-profit research organizations handle clinical trials, inventories, and remote adjudication processes. It enables researchers to upload case report forms and study documents, photos, and videos across existing data records.

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Clinicubes CTMS logo

Comprehensive CTMS for hospitals with focus on budgeting

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Designed and developed with the latest technologies Clinicubes CTMS simplifies the conduct of clinical trials, provides streamlined processes, and ensures fast and smooth workflows, saving a lot of time and effort, while avoiding errors.

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