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Encryption Software with HIPAA Compliant (2026)

Last updated: February 2026

Key features of Encryption Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • File Encryption: Reviewers value the ease of encrypting files, protecting sensitive data, and offering various encryption options for secure sharing. 97% of reviewers rated this feature as important or highly important.
  • Authentication: Users highlight the importance of two-factor authentication and integration with other platforms for enhanced security and ease of use. 96% of reviewers rated this feature as important or highly important.
  • Password Management: Reviewers appreciate the ability to securely manage multiple passwords, generate strong passwords, and centralize password control. 96% of reviewers rated this feature as important or highly important.
  • Data Security: Users emphasize the effectiveness of encryption in protecting sensitive data, preventing breaches, and ensuring secure file transfers. 94% of reviewers rated this feature as important or highly important.
  • Access Controls/Permissions: Reviewers mention the flexibility in setting permissions to control who can access, view, and modify files, ensuring confidentiality. 85% of reviewers rated this feature as important or highly important.
  • Compliance Management: Users note the importance of compliance features in adhering to regulations and mitigating risks associated with data breaches. 76% of reviewers rated this feature as important or highly important.
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45 software options

Diplomat Managed File Transfer logo

File sharing software for the healthcare and other sectors

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Diplomat MFT by Coviant Software is a secure, scalable managed file transfer solution. Automate SFTP, FTPS, HTTPS, and AS2 workflows, integrate with AWS or Azure, and meet HIPAA, PCI/DSS, or GDPR requirements, with zero breaches in 20+ years. Start your free trial today.

Read more about Diplomat Managed File Transfer

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Virtru logo

Cloud-based data privacy and security platform

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Virtru offers a range of data protection products that provide encryption, access controls, key management, and persistent audit to meet security and privacy needs. Supports HIPAA, GDPR, CCPA, ITAR, CJIS, NIST, FERPA and CCMC compliance & integrates seamlessly into the platforms you already use.

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MySQL logo

One database service for transactions, analytics, and ML

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MySQL is a relational database management system (RDBMS) designed to help businesses record, update, and manage data and deploy cloud-native applications. Features include data masking and de-identification, multi-document transaction support, intrusion detection, alerts & configuration management.

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Progress ShareFile logo

Secure file sharing and sync

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Progress ShareFile provides users with the ability to send, receive and share large business files securely. Through the ShareFile portal, offer clients a personalized, company-branded and password-protected platform from which to collaborate on files.

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JumpCloud Directory Platform logo

A cloud directory platform for secure access to resources

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Two-way TLS authentication and encryption to third-party assessments and independent audits (e.g. Type 1 SOC)

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Bitwarden logo
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The Most Trusted Open Source Password Manager for Business

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Bitwarden is an open source password manager that uses end-to-end encryption to enable users to securely store and share sensitive data.

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WebTitan logo

DNS-based web filter, malware/phishing protection & security

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DNS Based Web Security Layer

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GoAnywhere MFT logo

Managed File Transfer to secure and automate data exchanges.

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Fortra's GoAnywhere helps to encrypt enterprise files transfers and meet compliance requirements. Request a free demo today.

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GoodAccess logo
Category Leaders

Zero Trust Architecture as a Service

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Top-rated Zero Trust SASE/SSE for network security and regulatory compliance. Protect your business, anytime, anywhere.

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Cypherdog Encryption logo
Category Leaders

One click. Complete protection.

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Cypherdog Encryption (CE) provides the ability to encrypt and decrypt e-mails with attachments with confirmation of the identity of the parties to the communication.

No "trusted" third party, zero-knowledge security model, asymmetric encryption.

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Progress MOVEit logo
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Secure data & file transfer for enterprise-level users

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MOVEit Managed File Transfer (MFT) software provides secure collaboration and automated file transfers of sensitive data. Organizations get complete visibility of all file transfers along with automated workflows that can replace scripting.

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Proton Mail logo

Web-based email management platform

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ProtonMail is a web-based email management platform that helps businesses securely transmit encrypted emails between users both inside and outside of the organisation.

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Mailock logo
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Secure emails with encryption and recipient authentication

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Exchange confidential information securely using your existing email setup. Encrypt messages and authenticate recipients.

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Syxsense logo

Unified Security and Endpoint Management

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Syxsense is a leading USEM solution designed to help SecOps departments, MSPs, and IT professionals in organizations with 100-100,000 endpoints manage and secure their environment.

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ConnectWise SIEM logo

Threat detection and response management software

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ConnectWise SIEM is a threat detection and response management software designed to help enterprises create, launch, and manage cybersecurity programs. The platform enables organizations to identify potential threats and malicious activities across networks & connected devices via a unified portal.

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Proton VPN logo

VPN with DNS filter function and Secure Core architecture.

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Lock down sensitive data with Proton VPN. Everything is safe with unbreakable encryption — no leaks, no logs, no complexity.

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Sealit logo
Category Leaders

Full Security - Just 1 Click.

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Sealit protects your data, no matter how it's shared. End-to-end email and file encryption for small businesses or individuals.

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AxCrypt logo

AxCrypt, File encryption software, Password manager

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AxCrypt is a file encryption software that provides secure data storage and sharing. AxCrypt is designed to be user-friendly while maintaining a high level of encryption for sensitive information.

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EventSentry logo

Real-time log & event log hybrid SIEM monitoring solution

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EventSentry is a hybrid SIEM (security information & event management) solution which offers a range of tools including event log monitoring, reporting, health monitoring, compliance management, network monitoring, environment tracking, data consolidation, Active Directory integration & more

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Hushmail logo

Email, web form, and e-signature solution for healthcare

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Hushmail is a web-based email, web form, and e-signature service that enables businesses to send and receive encrypted client communications. The drag-and-drop form builder, template directory, and integrated e-signatures are perfect for healthcare, legal, and other fields requiring confidentiality.

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DriveStrike logo

Data and device protection for businesses of all sizes

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DriveStrike is a cloud-based data and device protection solution which helps businesses of all sizes with data security and compliance. Key features include incident management, policy management, automated device recognition, real time monitoring, and remote locking.

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Trustifi logo

Protect Your Business Emails with AI-Powered Security

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Email security solution that helps manage threat detection, regulatory compliance, data encryption, whitelisting/blacklisting, and more.

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Files.com logo

Automation-Focused Cloud Platform for Secure File Transfer

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Unlike "MFT" Competitors, Files.com runs entirely in the cloud, offering 7 storage regions & direct connectivity to Amazon S3, Azure, Google Cloud Platform, Box, Dropbox, Wasabi & On-Premise Storage.

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BlueFiles logo

File encryption and transfer for confidential data

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BlueFiles is a Managed File Transfer (MFT) solution based on end-to-end encryption.

BlueFiles enables users to send encrypted files securely. BlueFiles is secure, easy to use, and allows users 100% privacy in their file exchanges.

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GhostVolt logo

Powerful encryption software with all the features you need.

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GhostVolt Solo enables users to easily password-protect files, photos, tax and health records, tax forms, or any other digital file or document with seamless and proven 256-bit enterprise-level encryption.

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