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Top Rated Managed Service Providers (MSP) Software with Microsoft 365

Last updated: May 2026

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18 software options

Freshservice logo

A complete IT service management (ITSM) tool for business

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Freshservice is an online ITIL service desk with ticketing & asset management capabilities, and incident, problem, change, release, and knowledge management tools.

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N-central logo

On-premise and hosted RMM software for MSPs

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N-central is an endpoint detection and response software designed to help managed service providers (MSPs) prevent, detect, respond to, and recover from threats.

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Acronis Cyber Protect Cloud logo

AI-powered data protection and cybersecurity

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Acronis Cyber Protect Cloud is AI-powered cyber protection for modern MSPs, natively integrating operations management, cybersecurity and data protection in one platform.

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Comet Backup logo

Deliver Fast, Secure Data Protection

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Fast, secure backup software for MSPs & IT providers who want to offer Backup-as-a-Service (BaaS).

Comet is a flexible, all-in-one backup platform available in 13 languages. You choose your backup environment and storage destinations.

Simple, profitable pricing. No contracts. 30-day FREE trial!

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IT Glue logo

Track, find and know everything in under 30 seconds.

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IT Glue is a cloud-based, SOC 2-compliant IT documentation solution which is designed to help MSPs manage documentation and reduce time spent searching for information. The platform offers flexible asset tracking, relationship mapping, documentation automation, workflows, checklists, and more.

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ServoDesk logo

Help Desk, ITSM, Service and Support management for SMBs

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Simplisys ServoDesk is an IT service and support management platform for SMB's. Features include facilities management, an agile service desk, IT service management, employee relations, and an enterprise service desk for managing inter-departmental relationships and service requests.

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MSP360 Backup logo

Data Protection for MSPs And IT Teams

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MSP360 Managed Backup is a secure, scalable, and cost-effective backup solution that eliminates vendor lock-in, reduces maintenance time, and maximizes MSP profitability with flexible storage and automation.

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Inserve logo

100% Dutch Servicedesk software

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Inserve is online helpdesk software for managing the support department of MSP's and Agencies.

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Guardz logo

Cybersecurity solution

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Guardz is a managed cybersecurity solution built for MSPs to holistically protect and provide insurance coverage to SMEs with a holistic and multilayered approach.

The Guardz platform continuously monitors businesses' digital landscapes to safeguard their assets.

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Beyond DLP logo

Product Data Protection Beyond Boundaries

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Beyond DLP is a data protection platform to track and protect scattered data. ITsMine's software brings data protection to enterprises in a clear API-based solution.

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metricVOICE logo

Cloud Hosted Voice & UCaaS - metricVOICE by Fastmetrics

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metricVOICE by Fastmetrics - cloud hosted phones, VoIP & UCaaS. Backed by LIVE USA SUPPORT.

Connect how you work, where you work. The ESSENTIALS plan starts from $15 per month.

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Versio.io logo

CMDB, IT Asset Management, Governance, Security

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Versio.io continuously and automatically detects and documents changes in businesses and IT landscapes. Data from third-party applications that companies use to run business processes, monitor the IT landscape and control IT service management can be seamlessly integrated.

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Syxsense logo

Unified Security and Endpoint Management

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Syxsense is a leading USEM solution designed to help SecOps departments, MSPs, and IT professionals in organizations with 100-100,000 endpoints manage and secure their environment.

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JumpCloud Directory Platform logo

A cloud directory platform for secure access to resources

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Scale Your MSP Business - Your customers are moving to the cloud. Now, you can manage their systems, apps, networks, & more – all from one pane of glass.

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Deepser logo

IT service desk, CRM, and asset management software

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Efficiently manage tickets, track devices and their data, keep a complete overview of your clients' IT infrastructure, optimizing the use of company resources and time. Measure service data, check performance with reports and dashboards, respect KPIs and improve customer satisfaction.

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Alloy Navigator logo

Award winning IT Asset Mgmt and Service Mgmt platform

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Alloy Navigator is an all-inclusive IT Service and Asset Management solution that provides thoughtful answers to your toughest IT challenges.

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Accelo logo

Transform the way you manage client work

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Accelo combines the key needs of a CRM, project planning, contracts, service tickets, and more in one platform for Managed Service Providers in small to medium sized IT businesses. Save time by automating and gaining visibility into the performance of your IT services, from prospect to close.

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JIRA Service Management logo

IT service platform for unified support

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JIRA Service Management is an AI-based platform that unites teams to deliver exceptional service experiences. It helps managers scale support across IT, HR, engineering, and customer service with customizable help centers, automated workflows, and self-service tools. Featuring virtual agents and integration with Atlassian's teamwork graph, it connects people, work, and goals while reducing disruptions and improving incident resolution.

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