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Endpoint Protection Software Integrated with Microsoft 365 (2026)

Last updated: February 2026

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15 software options

Acronis Cyber Protect Cloud logo

AI-powered data protection and cybersecurity

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Integrates with Microsoft 365, ConnectWise Automate, Microsoft Azure, …

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Acronis Cyber Protect logo

Integrated data protection and cybersecurity in one solution

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Integrates with Microsoft 365, ConnectWise Automate, Microsoft Azure, …

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Rippling logo

Workforce management across HR, finance, and IT. 

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Integrates with Microsoft 365, monday.com, Vanta, …

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Iru logo

Collapse the IT stack with Iru.

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Integrates with Microsoft 365, Vanta, Scrut Automation, …

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JumpCloud Directory Platform logo

A cloud directory platform for secure access to resources

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Integrates with Microsoft 365, Auvik, Scrut Automation, …

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Splunk Enterprise logo

Machine data management and analytics

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Integrates with Microsoft 365, Auvik, Callgoose SQIBS, …

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Safetica logo

Intelligent Data Security

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Integrates with Microsoft 365, LogRhythm SIEM, IBM QRadar Incident Forensics, …

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OneLogin logo

Cloud-Based Identity Management & Single Sign-On System

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Integrates with Microsoft 365, Vanta, GaggleAMP, …

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N-central logo

On-premise and hosted RMM software for MSPs

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Integrates with Microsoft 365, Auvik, Passportal, …

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Syxsense logo

Unified Security and Endpoint Management

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Integrates with Microsoft 365, ServiceNow, Ansible Automation Platform, …

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ConnectWise SIEM logo

Threat detection and response management software

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Integrates with Microsoft 365, ConnectWise Automate, TRaViS, …

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Unitrends Backup logo

Data backup, recovery and protection solution

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Integrates with Microsoft 365, Microsoft Azure, IT Glue, …

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Chimpa logo

Unified Endpoint Manageme software for iOS & Android devices

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Integrates with Microsoft 365, IFTTT, Google Workspace, …

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Beyond DLP logo

Product Data Protection Beyond Boundaries

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Integrates with Microsoft 365, Google Workspace, Dropbox Business, …

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Microsoft Enterprise Mobility + Security logo

Enterprise mobility management (EMM) for Microsoft Azure

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Integrates with Microsoft 365, TRaViS, Microsoft Azure, …

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