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Clinical Trial Management Software with Enrollments/Onboarding (2026)

Last updated: March 2026

Key features of Clinical Trial Management Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • 21 CFR Part 11 Compliance: Reviewers emphasize the importance of 21 CFR Part 11 compliance for secure, trustworthy electronic records and signatures, ensuring regulatory adherence. 99% of reviewers rated this feature as important or highly important.
  • HIPAA Compliant: Users value HIPAA compliance for safeguarding patient privacy and maintaining ethical standards in clinical research. 96% of reviewers rated this feature as important or highly important.
  • Audit Trail: An effective audit trail feature helps users track changes, ensuring transparency and compliance during audits. 96% of reviewers rated this feature as important or highly important.
  • Electronic Data Capture: Reviewers appreciate real-time data capture, reducing errors and improving efficiency in clinical trials. 94% of reviewers rated this feature as important or highly important.
  • Document Management: Users highlight the ease of organizing, uploading, and retrieving documents, which streamlines regulatory inspections and daily operations. 94% of reviewers rated this feature as important or highly important.
  • Clinical Study Management: Reviewers find it essential for tracking study progress, managing sites, and ensuring data integrity throughout clinical trials. 92% of reviewers rated this feature as important or highly important.
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42 software options

Castor EDC logo

The top-rated EDC system in the world *EDC + ePRO + eConsent

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The only GCP & 21 CFR compliant system that's affordable for every researcher and has all the features of expensive systems. Start now.

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RealTime-CTMS logo

Cloud-based clinical trial management system

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RealTime-CTMS is an end-to-end clinical trial management system designed to streamline clinical study information and company processes

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Researchmanager – Clinical Research Suite logo

EDC, CTMS, eTMF, ePRO, RTSM, eConsent, RIMS, LIMS

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The Clinical Research Suite is an online platform tailored for managing clinical trials, facilitating organizations in planning, strategizing, and executing life science research. It empowers researchers to collect and analyze data in standardized formats, optimizing scientific research and decisio

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EDGE logo

Real-time clinical trial management with in-depth reporting

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An innovative cloud-based clinical trial management program providing fast access to real-time data across the globe.

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Ripple logo

Patient recruitment and management for clinical trails

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Ripple is a SaaS platform that automates patient recruitment, administrative tasks, and reporting activities for contract research organizations and academic centers that are conducting clinical research and trials, as well as translational and social studies.

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eClinPro CTMS & eSource logo

Clinical trials made simple, compliant, and efficient

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eClinPro CTMS & eSource is a clinical trial management system (CTMS) that helps research centers manage clinical studies.

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TrialKit logo

Unified eClinical platform with embedded intelligence

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TrialKit is a global, cloud-based development platform for end-to-end, "direct-from-source" data collection and workflow management across all phases of clinical trials.

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ClinCapture logo

Clinical trial platform for research teams

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Captivate is a clinical trial management platform that offers multiple integrated modules for conducting research studies. The software includes electronic data capture, electronic patient-reported outcomes, electronic consent, randomization and trial supply management, electronic trial master file, and medical coding capabilities. Captivate is designed to support organizations involved in clinical research operations.

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Clinical Conductor CTMS logo

Comprehensive Hybrid Clinical Trial Managment System (CTMS)

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Clinical Conductor CTMS (CC CTMS) is the most used by research sites worldwide. Part of the CCTrialSuite, CC CTMS is helping leading hospitals and health systems of every size or complexity to maximize their decentralized trial results. Optimize recruiting, enrollment, finances, reporting and more.

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CRIO logo

Clinical research regulatory workflow management software

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CRIO, the leader in eSource technology, is a health tech company helping pharma, biotech, research sites, and academic research centers streamline regulatory workflows with one system that delivers a single source of clinical data capture.

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Prelude EDC logo

Clinical trial management system for researchers

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Prelude EDC is a web-based EDC solution that helps researchers and clinicians with clinical trial management. Key features include electronic data capture, data management, project management, custom fields, audit trail, automatic notifications, and compliance management.

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Climedo  logo

Powerful, modular and secure solutions for DCTs.

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Climedo is a secure and modular cloud-based electronic data capture (EDC) tool for decentralized clinical trials. It enables the clinical validation and post-market surveillance of of medtech and pharma products using tools such as cOA/ePRO, eCRF, clinical study tracking, input forms, etc.

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Datacapt logo

One unified Platform. Datacapt is reimagining your Trials.

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Datacapt is an intuitive and easy-to-use EDC platform with eCRF, ePRO, eConsult, and eConsent. Access real-rime reports, high-quality data capture, and fully compliant.

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Jeeva eClinical Cloud logo

Streamline and automate clinical trials with software and AI

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Jeeva eClinical cloud helps clinical researchers, CROs, and Biopharma sponsors to accelerate the clinical trial process from patient screening and enrollment, clinical data capture, protocol scheduling, patient adherence, and retention with user-friendly software, integrations, and Agentic AI.

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AQ Platform logo

Clinical trial management software

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AQ is a clinical trial management solution integrating multiple modules for study management, operations, recruitment, electronic investigator site file (eISF) and patient source file (PSF), and reporting. It offers real-time analytics to gain visibility into data-driven insights for optimized trial accuracy.

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Flex Databases platform logo

Unified platform for handling clinical trials and documents

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One system for clinical development process and beyond. Scalable and flexible CTMS with all the features you may need. Cloud based and on-premises options. Validated and complaint with regulations.

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Studypages logo

Cloud and mobile-based clinical research software

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Studypages is a cloud and mobile-based clinical research management platform that helps simplify clinical operations and connect participants, sites, and sponsors in one place.

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MainEDC logo

EDC, IWRS, Drug Supply, Logistic and ePRO Cloud Platform

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Cloud-based EDC, IWRS, Drug Supply, Logistic, ePRO, Registries, PharmMarketing, eConsent, eCOA, eSource easy-to-use and powerful integrated platform.

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RAYLYTIC Platform logo

Medical Data Automation

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The UNITY platform contains modules for clinical study planning, PROM/CRF collection, and an advanced module for the highly precise, AI-supported analysis of medical images (X-Ray, CT, MRI).

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SimpleTrials CTMS/eTMF logo

Web-based CTMS & eTMF Solution

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SimpleTria is a web-based Clinical Trial Management System (CTMS) designed to support the biotechnology, pharmaceutical and device industries. It provides intuitive, project management tools that bridge clinical expertise with technical expertise in software development. SimpleTria provides a flexible, scalable, and easily adaptable eClinical management system which will improve study management efficiencies and reduce operating costs.

Read more about SimpleTrials CTMS/eTMF

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DFdiscover logo

Clinical data management system for research organizations

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DFdiscover is a clinical data management system which helps academic and non-profit research organizations handle clinical trials, inventories, and remote adjudication processes. It enables researchers to upload case report forms and study documents, photos, and videos across existing data records.

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Trial 360 logo

Site operations and compliant CTMS software

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Trial 360 for research sites is an all-in-one, web-based compliant software. This robust tool streamlines workflows and improves quality across clinical trial conduction and site operations.

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BSI CTMS logo

The most efficient tool for your clinical trials

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BSI CTMS is a clinical trial management system with integrated eTMF, eMVR & Trial Supply Management for Pharma, MedTech, BioTech, CROs, and research hospitals.

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TrialX logo

Platform for managing clinical trial operations

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TrialX allows organizations to manage their clinical trial process. It offers TrialX Connect and TrialX Advance to streamline operations related to patient recruitment management and remote research data collection management.

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ClinVigilant eClinical logo

Cloud cost-effective platform to manage clinical trials

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Streamline your clinical studies, reduce set-up times and capture compliant data automatically from multiple sources with ClinVigilant eClinical. Simple, user-friendly & scalable tools.

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