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Top Rated Server Backup Software with Differential backup

Last updated: May 2026

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31 software options

NinjaOne logo

NinjaOne

Unified endpoint management & IT automation platform

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NinjaOne is a unified IT management platform designed for enterprise IT teams and managed service providers. The software consolidates endpoint management, autonomous patch management, remote monitoring and management, backup solutions, and mobile device management into a single console. It includes features such as policy-based control, automated ticketing, cross-platform remote access, and integrations with third-party security and service desk tools.

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VM Backup logo

Virtual machine backup and replication for Hyper-V & VMware

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Altaro VM Backup is a virtual machine backup & replication solution for Microsoft Hyper-V & VMware environments. The cloud-based platform ensures business data is always secure with automatic backup, WAN-optimized replication, cloud storage management, continuous data protection (CPD), and more.

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GRBackPro logo

Windows-based data backup software.

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GRBackPro is a Windows-based data backup software that helps businesses and individuals schedule backup jobs, monitor job status, restore data, and more. It lets users select backup destinations, add relevant notes, handle file logs and archive as well as verify files from a unified platform.

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Comet Backup logo

Deliver Fast, Secure Data Protection

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Fast, secure server backup software for businesses and IT providers.

Comet is a flexible, all-in-one backup platform available in 13 languages. You choose your backup environment and storage destinations.

Simple, profitable pricing. No contracts. 30-day FREE trial!

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HYCU R-Cloud logo

Data anywhere. Protected everywhere.

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HYCU is the fastest growing leader in the multi-cloud and SaaS data protection-as-a-service industry.






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Backblaze B2 Cloud Storage logo

Always-hot cloud storage to store, manage, and protect data

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A leading specialized cloud provider that makes it easy for businesses to store, use, and protect their data. Over 100K customers in 175 countries use B2 Cloud Storage to host content, build & run applications, manage media, back up & archive data, and protect and recover from ransomware attacks.

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Plesk logo

Simplified WebOps and web hosting

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Plesk is a WebOps and hosting platform designed to help users run, grow and automate their apps, sites, and business. The software offers a full set of technical, security and automation tools in a single hosting platform, including full & incremental backups, resource usage monitoring, and more.

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MSP360 Backup logo

Data Protection for MSPs And IT Teams

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MSP360 Managed Backup is a secure, scalable, and cost-effective backup solution that eliminates vendor lock-in, reduces maintenance time, and maximizes MSP profitability with flexible storage and automation.

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Vinchin Backup & Recovery logo

Easy-to-use & Powerful VM Backup Software.

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Vinchin Backup & Recovery is an enterprise-level data protection solution delivering comprehensive backup and disaster recovery strategies for your entire workloads including most mainstream virtualizations, databases, massive files, physical servers, and NAS devices in multiple environments.

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NovaBACKUP Server Agent logo

Local and Cloud Windows Server Backup

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NovaBACKUP Server Agent is a secure, flexible, and comprehensive solution for Windows Server, MS-SQL, Exchange, Hyper-V, and VMware backup. It provides fast, reliable, and all-inclusive data protection for physical servers and virtual machines with local and cloud storage (250GB of cloud included).

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Unitrends Backup logo

Data backup, recovery and protection solution

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Unitrends Server Backup - a prepackaged virtual appliance with integrated, backup, replication, deduplication, archive & instant recovery. Features include pattern recognition, predictive analytics, email alerts, and data replication and deduplication.

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EDpCloud logo

Real-Time Cross-Platform Replication and Synchronisation.

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Real-time cross-platform file replication, data distribution, and file synchronization between different operating systems, different cloud providers, and different geographic sites.

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Macrium Reflect Server logo

Server backup solution for Windows operating systems.

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Macrium Reflect Server is a server backup solution that provides full image, file, and folder-level restores for business-critical servers in a commercial environment. Designed for endpoint backup, Macrium Reflect Server offers a reliable way to recover everything from individual files to entire Windows Operating Systems. It provides virtual booting of backup images, allowing users to create, start, and manage Microsoft Hyper-V virtual machines.

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Cove Data Protection logo

Cloud-first data protection as a service

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Back up physical and virtual servers to our private cloud. Manage server, workstation and Microsoft 365 backups from one web-based console.

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Resilio Active Everywhere logo

Data transfer & synchronization for enterprises

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Resilio Connect is a scalable solution for automated server backup, moving data and syncing files. Securely backup critical data -- from millions of small files to terabyte server files. Resilio is trusted by many small and large companies, including Microsoft, Caterpillar, Cisco and Mercedes.

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Zmanda logo

Enterprise Backup and Recovery Solution

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Zmanda Pro is an enterprise-class backup, recovery, and data resiliency solution designed for businesses seeking robust protection without complexity.

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CyberFortress logo

Data, mobile & SaaS backup solutions, with disaster recovery

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KeepItSafe provides corporate business and Enterprise users with a holistic approach to data protection and security with a suite of services across hybrid online backups, disaster recovery as-a-Service, endpoint protection, mobile device backup, plus Cloud2Cloud backup of SaaS applications

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UltraBac logo

Backup and disaster recovery management software

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UltraBac is a backup software designed to help businesses of all sizes streamline data replication, disaster recovery management, and virtual backup operations. It enables professionals to mount image backups for folder recoveries and replicate data on various external applications such as Microsoft Azure, VMWare vSphere, and Hyper-V.

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Quorum onQ logo

Data backup and disaster recovery solution

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Quorum onQ is a backup and data recovery solution designed to help enterprises recover critical business data after storage, system, or site failure. The application enables IT professionals to schedule backups, configure workflows, maintain backup logs, and streamline data encryption operations via a unified platform.

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Commvault Cloud logo

Total Resilience. No Exceptions.

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Commvault® Cloud is the industry’s only platform for cyber resilience, built to meet the demands of the hybrid
enterprise at the lowest TCO, in the face of ransomware and other cyber threats.

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EaseUS Todo Backup Server logo

Windows server data backup software for businesses.

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EaseUS Todo Backup Server is a reliable data backup solution that helps protect and keep businesses running by automated backups and instant restoring from disaster. It covers four editions - Workstation, Server, Advanced Server, and Technician - suitable for different business sizes and environments, providing comprehensive protection for business-critical PCs and servers.

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Cloud Volumes ONTAP logo

Enterprise data storage management and encryption solution

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Cloud Volumes ONTAP is a cloud-based enterprise data management solution which assists medium to large sized businesses with data storage and encryption. Its key features include data synchronization, file sharing, information governance, disaster recovery, thin provisioning and compression.

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Cohesity logo

Server backup and data management software

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Cohesity is a leader in AI-powered data security and management, protecting the world’s most critical data workloads.

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Iperius Backup logo

Backup solution for databases, servers and workstations

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Iperius Backup is a data backup and recovery suite which helps small to large businesses with backups for image files and data restoration. Key features include hard drive cloning, data synchronization, scheduling, user authentication, backup verification, and file transfer.

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BDRSuite logo

#1 Robust & Cost-Effective Backup & DR Software.

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BDRSuite is a cost-effective, comprehensive Backup and Disaster Recovery solutions for businesses and service providers. It is designed to protect various IT workloads, including VMs, servers, endpoints, SaaS apps, cloud VMs, and databases.

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