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Top Rated Chemical Manufacturing Software with Mid size business

Last updated: May 2026

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42 software options

Guidewheel logo

Guidewheel

AI-enabled and cloud-based factoryOps platform

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Guidewheel is a cloud-based and AI-enabled factoryOps platform that enables factories to reach sustainable peak performance. The platform provides visibility across all operations and helps deliver return on investment (ROI).

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MasterControl Manufacturing Excellence logo

MasterControl Manufacturing Excellence

SaaS manufacturing and production scheduling software

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MasterControl Manufacturing Excellence is a SaaS platform designed to help businesses streamline inventory tracking, resource planning, and supply chain operations. The integrated EBR module enables manufacturers to organize electronic batch records (EBR) and conduct quality checks.

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Intuiflow logo

Empowering supply chain leaders to achieve tangible results.

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End-to-end Supply Chain Software for manufacturers and distributors that provides superior materials planning, demand planning, S&OP and production scheduling capabilities in an intuitive platform. Integrates with all ERPs.

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Acumatica Cloud ERP logo

Cloud-based enterprise resource planning software

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Acumatica Cloud ERP supports chemical manufacturing with Formula Management, Material Ordering, Inventory Control, and Lot Tracking. It ensures Traceability, aids Compliance Management, and integrates processes seamlessly with robust ERP Integration.

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SmartMon logo

Intuitive MES/OEE system for real-time production control.

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Smartmon is a MES/OEE platform developed under the concept of User friendly, being intuitive and easy to use. Software designed to help businesses of all sizes capture data from manufacturing machines and store it in a centralized repository to gauge productivity.

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Datacor ERP logo

ERP Software - Process Manufacturers, Chemical Distributors

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Datacor ERP is a web-based ERP solution specifically designed for the process manufacturing and chemical distribution industries.

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Asprova logo

Production scheduling management software

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Asprova APS is a production scheduling system for the efficient creation of multi-product and process schedules. It seamlessly integrates with ERPs, optimizes processes, tracks resource utilization, and provides visibility into daily schedules, driving productivity and increasing efficiency.

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Mar-Kov logo

Cloud-based & on-premise MRP tool for chemical manufacturers

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Software that mondernizes Manufacturing at batch and process manufacturers. Scale up without extra staff using Mar-Kov.

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LogicBox logo

Custom-built business management software.

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Custom business management software that simplifies. One simple system to incorporate all facets of your workflows, from account management to invoicing to payment processing. Best of all, because Logicbox builds a system specifically for you, choose only the modules you need, with no bloatware.

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TME CMMS logo

One Platform. Zero Spreadsheets. Total Visibility.

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Traceability Made Easy® (TME®) CMMS is a cloud-based asset management software that specializes in utilization, warehouse and inventory management, SPC/SQC and maintenance management.

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Sage X3 logo

Cloud-based enterprise resource planning solution

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Sage X3 is a cloud-based solution designed to help businesses within manufacturing, distribution, chemical & food & beverage sectors manage business operations, including accounting, payroll, purchasing, budgeting, quality control, and more.

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FactoryTalk View logo

Cloud-based HMI solution for manufacturing companies.

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FactoryTalk View HMI Software delivers real-time visualization for industrial automation. It includes Site Edition for supervisory monitoring, Machine Edition for machine-level interfaces, and ViewPoint for secure web access. With rich graphics, a shared programming language, and faceplate libraries, it ensures consistent operational views. Supporting process, batch, and discrete applications, it helps operators, technicians, and engineers make informed decisions with timely production data.

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Petrofly logo

Put Wings on our Energy Operation

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The oil and gas software made for upstream, midstream, and downstream companies. Streamline your operational tasks and remove bottlenecks.

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Axolt logo

Axolt — Run your business operations inside Salesforce.

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Axolt is a Salesforce-native application that unifies supply chain, inventory, manufacturing, finance, and operations into one smart, scalable solution. Trusted by fast-growing businesses across industries, Axolt delivers real-time visibility, intelligent automation, and seamless collaboration.

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BatchMaster logo

ERP software for recipe- and formula-based manufacturing

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BatchMaster offers cloud and on-premise ERP software solutions for recipe- and formula-based manufacturers, such as those in food and beverage, chemicals, cosmetics, paints, nutraceuticals, pharmaceuticals, and others. It is pre-configured and provides a fully integrated suite of purchasing, financials, distribution, sales, quality management, and other applications.

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24SevenOffice logo

Online project and business management software

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All business applications integrated in one system!

* CRM tool
* Accounting
* Invoice
* Online Project Management Software
* E-mail
* Calendar
* File/documents

Contact us for a trial or a demonstration.

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Opcenter Execution Process logo

Manufacturing execution system for process industries

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Opcenter Execution Process is a manufacturing execution system designed specifically for process manufacturing industries including consumer packaged goods, food and beverage, and chemical manufacturing.

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Kenandy Cloud ERP logo

Now You Can With Kenandy

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Built on the Salesforce platform, Kenandy’s ERP adapts to how a business operates today and empowers them to be ready for growth.

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R4 Enterprise logo

Enterprise resource planning (ERP) solution

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R4 Enterprise is an enterprise resource planning (ERP) solution that helps businesses streamline operations related to inventory management, manufacturing execution, financial planning, and more on a centralized platform. It enables staff members to utilize the built-in CRM tool to track sales processes and access customer information to optimize overall businesses operations.

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Business Manager Enterprise (BME) logo

Complete Business Management solution (CRM, ERP, MRP, WHM)

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BME allows companies to manage all aspects of their business from prospect first contact to invoice. Supply chain, inventory, and warehousing, along with Human Resources, Project Management, Asset and Service Management, plus much more..

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Enterprise 21 ERP logo

Enterprise resource planning software for SMBs

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Enterprise 21 ERP is a supply chain management software designed to help small and midsize businesses manage warehouse, inventory, finance, manufacturing, and customer relationships. The platform enables administrators to receive, select, replenish, and ship stocks.

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SAP S/4HANA Cloud logo

A complete, intelligent ERP system for enterprises.

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SAP S/4HANA Cloud is a cloud-based intelligent ERP system specifically developed for companies in all industries offering them a broad and flexible functionality.

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Oracle Fusion Cloud PLM logo

Agile product lifestyle management software

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Oracle Fusion Cloud PLM is a cloud-based product lifecycle management solution for managing the product value chain. The platform helps users innovate profitably, centralize product data, streamline processes, and launch quality products.

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Accolade logo

Cloud-based InnovationOps software for portfolio planning

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Accolade® is an InnovationOps software product that empowers innovation,
product, and R&D teams to advance portfolio planning.

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Nexelem logo

Manufacturing Management Software with Gen-Z-enabled UI/UX

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Nexelem offers a specialized suite of manufacturing software – MES, APS, WMS, and KPI Dashboards – fostering efficient production planning and streamlined material flow management. It cuts production costs by adeptly handling material demand and adhering to schedules.

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