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Clinical Trial Management Software with Audit Management (2026)

Last updated: March 2026

Key features of Clinical Trial Management Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • 21 CFR Part 11 Compliance: Reviewers emphasize the importance of 21 CFR Part 11 compliance for secure, trustworthy electronic records and signatures, ensuring regulatory adherence. 99% of reviewers rated this feature as important or highly important.
  • HIPAA Compliant: Users value HIPAA compliance for safeguarding patient privacy and maintaining ethical standards in clinical research. 96% of reviewers rated this feature as important or highly important.
  • Audit Trail: An effective audit trail feature helps users track changes, ensuring transparency and compliance during audits. 96% of reviewers rated this feature as important or highly important.
  • Electronic Data Capture: Reviewers appreciate real-time data capture, reducing errors and improving efficiency in clinical trials. 94% of reviewers rated this feature as important or highly important.
  • Document Management: Users highlight the ease of organizing, uploading, and retrieving documents, which streamlines regulatory inspections and daily operations. 94% of reviewers rated this feature as important or highly important.
  • Clinical Study Management: Reviewers find it essential for tracking study progress, managing sites, and ensuring data integrity throughout clinical trials. 92% of reviewers rated this feature as important or highly important.
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63 software options

Castor EDC logo

The top-rated EDC system in the world *EDC + ePRO + eConsent

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The only GCP & 21 CFR compliant system that's affordable for every researcher and has all the features of expensive systems. Start now.

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Viedoc logo

Electronic data capture for clinical trials

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Viedoc delivers powerful eClinical solutions that streamline clinical trials, making data collection, management, and analysis faster and easier. Trusted in 75+ countries, powering 7,000+ studies with more than 1.6M+ participants.

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Florence eBinders is a cloud-based solution designed to help businesses digitize their duty binder workflows via a unified portal. The platform allows organizations to remotely access, monitor, and source review data from sponsors.

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Researchmanager – Clinical Research Suite logo

EDC, CTMS, eTMF, ePRO, RTSM, eConsent, RIMS, LIMS

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The Clinical Research Suite is an online platform tailored for managing clinical trials, facilitating organizations in planning, strategizing, and executing life science research. It empowers researchers to collect and analyze data in standardized formats, optimizing scientific research and decisio

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ShareCRF logo

EDC software for clinical research

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Take control of your clinical trial data with ShareCRF. Configure your study in hours—no coding or external help needed. Enjoy an intuitive interface, full regulatory compliance, and unmatched adaptability to fit your unique study needs. Simplicity, efficiency, and reliability in one platform.

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Medrio logo

Powering your research potential.

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Medrio is an electronic data capture (EDC) tool for clinical research teams with tools for capturing, storing, analyzing, & managing patient data during clinical trials. Medrio offers secure storage of patient data, automates regulatory compliance management & allows users to build custom studies.

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EDGE logo

Real-time clinical trial management with in-depth reporting

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An innovative cloud-based clinical trial management program providing fast access to real-time data across the globe.

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Ripple logo

Patient recruitment and management for clinical trails

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Ripple is a SaaS platform that automates patient recruitment, administrative tasks, and reporting activities for contract research organizations and academic centers that are conducting clinical research and trials, as well as translational and social studies.

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eClinPro CTMS & eSource logo

Clinical trials made simple, compliant, and efficient

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eClinPro CTMS & eSource is a clinical trial management system (CTMS) that helps research centers manage clinical studies.

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TrialKit logo

Unified eClinical platform with embedded intelligence

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TrialKit is a global, cloud-based development platform for end-to-end, "direct-from-source" data collection and workflow management across all phases of clinical trials.

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ClinCapture logo

Clinical trial platform for research teams

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Captivate is a clinical trial management platform that offers multiple integrated modules for conducting research studies. The software includes electronic data capture, electronic patient-reported outcomes, electronic consent, randomization and trial supply management, electronic trial master file, and medical coding capabilities. Captivate is designed to support organizations involved in clinical research operations.

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Health Cloud logo

Patient relationship management software in the cloud

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Salesforce Health Cloud is a collaborative, all-round healthcare CRM and patient management software for healthcare providers, payers, and patients

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Prelude EDC logo

Clinical trial management system for researchers

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Prelude EDC is a web-based EDC solution that helps researchers and clinicians with clinical trial management. Key features include electronic data capture, data management, project management, custom fields, audit trail, automatic notifications, and compliance management.

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Datacapt logo

One unified Platform. Datacapt is reimagining your Trials.

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Datacapt is an intuitive and easy-to-use EDC platform with eCRF, ePRO, eConsult, and eConsent. Access real-rime reports, high-quality data capture, and fully compliant.

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Florence eTMF logo

Improve study workflows with the industry-standard eTMF

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Emerging and scaling organizations demand eTMF workflows that adjust to their processes. We don’t force you into a box. You choose how you work in our platform, and you can trust you’re always compliant with global regulations.

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Jeeva eClinical Cloud logo

Streamline and automate clinical trials with software and AI

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Jeeva eClinical cloud helps clinical researchers, CROs, and Biopharma sponsors to accelerate the clinical trial process from patient screening and enrollment, clinical data capture, protocol scheduling, patient adherence, and retention with user-friendly software, integrations, and Agentic AI.

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AQ Platform logo

Clinical trial management software

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AQ is a clinical trial management solution integrating multiple modules for study management, operations, recruitment, electronic investigator site file (eISF) and patient source file (PSF), and reporting. It offers real-time analytics to gain visibility into data-driven insights for optimized trial accuracy.

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Agatha Applications logo

Solution for clinical and quality operations

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Agatha provides a suite of applications for biotech, pharmaceutical, and medical device companies to manage their processes. Agatha applications include Solution Manager, Formulary Management, Quality Control Reporting, Clinical Research Management and Regulatory Compliance.

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EMR, Practice Management, behavioral, educational and mental health data collection software including curricula.

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STARLIMS logo

Clinical trial management software for laboratories

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STARLIMS is a laboratory information management system that helps businesses interpret and manage clinical data. The platform enables managers to handle clinical trials, research and development (R&D), and manufacturing processes.

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Flex Databases platform logo

Unified platform for handling clinical trials and documents

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One system for clinical development process and beyond. Scalable and flexible CTMS with all the features you may need. Cloud based and on-premises options. Validated and complaint with regulations.

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Macro logo

Cloud-based electronic data capture for clinical research

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MACRO, by Elsevier, is an electronic data capture solution that helps clinical research with data entry, customer support, compliance, audit, data management, system security, & more. The platform enables users to input, monitor, & run reports to derive insights from subject data.

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CRFweb logo

Electronic data capture software for clinical trials

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CRFWEB is an electronic data capture (EDC) software that helps organizations collect, manage, and analyze clinical data in compliance with FDA guidelines. With the eCRF module, staff members can handle queries, formulas, audit logs, edit checks, and more from within a centralized dashboard.

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Florence SiteLink logo

Remote clinical research site monitoring software

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Florence SiteLink is a remote site monitoring software designed to help medical institutions and clinical research assistants (CRAs) monitor multiple study sites via a centralized portal. SiteLink provides real-time data on each site’s status, including temperature, humidity, CO2 levels, power usage, and more.

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Data+ logo

Data management system for clinical research & bio-banks

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Data+ Research is a fully compliant & customizable application development platform for health and life-science industries, offering a wide range of apps for clinical data management, drug development, patient registries, biobank and lab management and more

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