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Patient Portal Software with One-to-One Messaging (2026)

Last updated: April 2026

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Key features of Patient Portal Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • Appointment Management: Users value customizable booking options, online self-scheduling, easy rescheduling, and automated reminders for efficient appointment handling. 98% of reviewers rated this feature as important or highly important.
  • Billing & Invoicing: Reviewers highlight ease of use, automated billing, integration with payment processors, and the ability to store credit cards for quick payments. 96% of reviewers rated this feature as important or highly important.
  • HIPAA Compliant: Users emphasize the importance of data security, privacy, and compliance with HIPAA regulations for protecting patient information. 96% of reviewers rated this feature as important or highly important.
  • Appointment Scheduling: Reviewers appreciate intuitive scheduling, customizable time slots, direct chart scheduling, and automated reminders for smooth appointment handling. 95% of reviewers rated this feature as important or highly important.
  • Document Management: Users find value in easily uploading, organizing, and accessing documents, maintaining a paperless office, and customizable document templates. 94% of reviewers rated this feature as important or highly important.
  • Charting: Reviewers highlight intuitive charting with customizable templates, efficient note-taking, and easy access to patient records for streamlined workflows. 92% of reviewers rated this feature as important or highly important.
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41 software options

SimplePractice logo
Category Leaders

Appointment scheduling and reminder solution

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SimplePractice is an all-in-one practice management solution that helps businesses simplify administrative tasks, such as scheduling, billing, and documentation, allowing health and wellness professionals to focus on providing excellent client care. The platform offers a robust set of features designed to help practitioners thrive.

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Mend logo
Category Leaders

The #1 Telehealth, Patient Engagement, & Automated Payments

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Single Digit No-Show Rates: Digital Forms, Telehealth, Appointment Reminders, &Patient Self-Scheduling. #1 Customer Rated Support & Custom Workflows.

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Pabau logo
Category Leaders

Practice management system for healthcare

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Pabau is an all-in-one practice management software designed for healthcare businesses. The system offers digital patient records, online booking capabilities, calendar management, and integrated payment processing to streamline administrative workflows. Pabau also includes marketing tools, inventory management, and reporting features that help medical practices operate efficiently while maintaining secure patient data.

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TheraNest logo
Category Leaders

Mental health practice management solution

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Prioritize clients, not paperwork. Therapists lose 8+ hours a week to admin tasks and 18% of revenue to billing inefficiencies—fueling burnout and making care harder to access. You deserve better. TheraNest automates and simplifies busy work so you can focus on being a therapist again.

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IntakeQ logo

Web-based intake forms management software

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IntakeQ is an online intake form solution that enables healthcare professionals to securely exchange electronic forms with their patients prior to appointments

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NextGen Office logo
Category Leaders

Empowering our clients to make healthcare better

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NextGen Healthcare provides ambulatory practices with award-winning solutions along with dedicated support & professional services.

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RXNT logo
Category Leaders

Cloud-based Practice Management, EHR, and eRx Software

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RXNT's cloud-based Patient Portal tool—part of our EHR system—boosts patient satisfaction, expands doctor-patient communication, and improves convenience. Empower your patients to easily schedule appointments, send secure messages, review lab results, sign documents and forms, and pay bills online.

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vcita logo
Category Leaders

Appointment scheduling and reminder solution

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Customize your patient portal with your logo / clinic colors. Let patients log in and schedule consultations, sessions, book and pay, see the history with past interactions - 24/7 from any device.

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Klara logo

Patient engagement platform

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Klara’s patient engagement helps practices communicate with patients more effectively than a patient portal — and no log-in required!

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DrChrono logo

Cloud healthcare management platform

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DrChrono is a cloud-based healthcare platform that integrates electronic health records, practice management, and medical billing functionalities. The system offers customizable clinical notes, telehealth capabilities, and specialty-specific templates for medical practices of various sizes. DrChrono provides mobile accessibility through iOS apps, allowing healthcare providers to manage patient care from multiple devices.

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Office Practicum logo

Pediatric practice management & EHR solution

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Office Practicum is a comprehensive pediatric management solution designed to help practices organize EHR, control billing & simplify patient engagement

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Practice Better logo
Category Leaders

EHR & Practice Growth Software

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Practice Better is the leading all-in-one practice management software solution transforming how health and wellness professionals run their practices and support their clients.

Try any paid plan free for 14 days.

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Healthie logo

HIPAA compliant health records for providers

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Healthie is a HIPAA-compliant electronic health record platform for health and wellness providers, including private practices, group practices, and digital health startups. It offers cloud-based charting, scheduling, billing, telehealth, patient engagement tools, and workflow automation. Features include an AI scribe, multi-provider support, insurance management, and integrations with third-party apps like wearable devices and business intelligence tools.

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AlayaCare logo

End-to-end home care software

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AlayaCare’s unique home care software offers a complete solution to manage the entire client lifecycle in a secure, integrated cloud-based system.

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Healee logo

Healee Patient Access

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Healee is an integrated patient access solution with robust 24/7 self-scheduling, powerful rule-based patient-provider matching and sophisticated calendar management.

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MediOffice logo

Next-generation practice management software

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MediOffice is the modern practice management solution for the modern practice. The software is packed full of features to streamline your practice saving you time and money. Our hero features include in-built dictation transcription, patient portal and online booking.

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My Best Practice logo

Software for managing healthcare operations and records

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My Best Practice, the EHR for evidence-based clinicians, simplifies creating and maintaining client accounts, scheduling appointments, managing client information, billing, and more.

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Legwork logo

Cloud-based Dental Patient Engagement Suite of Applications

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Legwork is your one-stop shop for attracting, retaining, and delighting patients. Integrate your patient engagement software, dental marketing, websites, and office phones with Legwork innovative solutions.

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Nexus EHR logo
Category Leaders

Certified, Modern and affordable healthcare platform.

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Nexus Patient portal allows patients to view their past visit details, request appointments, self-service update to their record, fill online forms and make payments.

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Elation logo

Clinical-First EHR & Billing Software

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Elation Health is the leading platform for primary care, empowering 32,000 clinicians to deliver personalized care to over 16 million patients. With a clinical-first EHR, integrated billing, and AI-powered tools, Elation simplifies care workflows to help independent practices thrive.

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Pomelo Health logo

A fresh approach to patient engagement.

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Pomelo by TELUS Health is a patient engagement platform that automates online booking, reminders, secure messaging and digital intake helping clinics reduce admin work and improve the patient experience.

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DENmaar Guardian logo

DENmaar wants to be a true partner in your practices growth.

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DENmaar is different. Our EHR & Insurance Revenue Cycle system is designed for 6+ MH/SA providers, including medical EMR for Psychiatry and e-prescription, a wide variety of therapy progress notes - including Wiley Planners. We are reimbursed by claims revenue produced. Plus credentialing services.

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PtEverywhere logo

All-in-one growth Solution for physical therapy clinics

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PtEverywhere is an all-in-one growth solution designed for physical therapy practices.

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Semble logo

Cloud-based clinic management system

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Semble is a cloud-based clinic management system, that helps healthcare practices manage patient data and administrative tasks, generate invoices, and process payments. Features include reminders, task allocation, questionnaire creation, access control, activity log, and user management.

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ClearGage logo

Comprehensive healthcare payments technology solution

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ClearGage cloud-based healthcare financial technology solutions optimize financial performance of small to mid-size healthcare organizations through automated patient billing, configurable payment solutions, online payment portals and integrations with EHR and practice management software vendors.

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