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Top Rated Patient Portal Software with One to one messaging

Last updated: May 2026

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42 software options

SimplePractice logo

SimplePractice

Appointment scheduling and reminder solution

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SimplePractice is an all-in-one practice management solution that helps businesses simplify administrative tasks, such as scheduling, billing, and documentation, allowing health and wellness professionals to focus on providing excellent client care. The platform offers a robust set of features designed to help practitioners thrive.

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TheraNest logo

TheraNest

Mental health practice management solution

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Prioritize clients, not paperwork. Therapists lose 8+ hours a week to admin tasks and 18% of revenue to billing inefficiencies—fueling burnout and making care harder to access. You deserve better. TheraNest automates and simplifies busy work so you can focus on being a therapist again.

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RXNT logo

RXNT

Cloud-based Practice Management, EHR, and eRx Software

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RXNT's cloud-based Patient Portal tool—part of our EHR system—boosts patient satisfaction, expands doctor-patient communication, and improves convenience. Empower your patients to easily schedule appointments, send secure messages, review lab results, sign documents and forms, and pay bills online.

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Practice Better logo

Practice Better

EHR & Practice Growth Software

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Practice Better is the leading all-in-one practice management software solution transforming how health and wellness professionals run their practices and support their clients.

Try any paid plan free for 14 days.

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myHealthPointe logo

myHealthPointe

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Web-based patient engagement app

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myHealthPointe Portal is a consumer-friendly web portal that provides individuals with access to their health plan and recovery through a user-friendly, secure solution. With myHealthPointe Portal, you can request appointments, receive reminder notifications and launch telehealth sessions. The consumer engagement portal connects individuals directly to their treatment through the convenience of their mobile devices.

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EHRYourWay logo

Streamlined care for mental health professionals.

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EHR YOUR WAY is a fully integrated behavioral health and clinical care EHR software. It is configurable for mental health and clinical health specific needs and is an ONC certified cloud-based EHR. EHR YOUR WAY is trusted by mental health professionals nationwide and is suitable for behavioral health agencies with 15 or more users.

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Pabau logo

Practice management system for healthcare

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Pabau is an all-in-one practice management software designed for healthcare businesses. The system offers digital patient records, online booking capabilities, calendar management, and integrated payment processing to streamline administrative workflows. Pabau also includes marketing tools, inventory management, and reporting features that help medical practices operate efficiently while maintaining secure patient data.

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Mend logo

The #1 Telehealth, Patient Engagement, & Automated Payments

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Single Digit No-Show Rates: Digital Forms, Telehealth, Appointment Reminders, &Patient Self-Scheduling. #1 Customer Rated Support & Custom Workflows.

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IntakeQ logo

Web-based intake forms management software

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IntakeQ is an online intake form solution that enables healthcare professionals to securely exchange electronic forms with their patients prior to appointments

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Klara logo

Patient engagement platform

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Klara’s patient engagement helps practices communicate with patients more effectively than a patient portal — and no log-in required!

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Healee logo

Healee Patient Access

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Healee is an integrated patient access solution with robust 24/7 self-scheduling, powerful rule-based patient-provider matching and sophisticated calendar management.

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My Best Practice logo

Software for managing healthcare operations and records

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My Best Practice, the EHR for evidence-based clinicians, simplifies creating and maintaining client accounts, scheduling appointments, managing client information, billing, and more.

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MediOffice logo

Next-generation practice management software

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MediOffice is the modern practice management solution for the modern practice. The software is packed full of features to streamline your practice saving you time and money. Our hero features include in-built dictation transcription, patient portal and online booking.

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Legwork logo

Cloud-based Dental Patient Engagement Suite of Applications

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Legwork is your one-stop shop for attracting, retaining, and delighting patients. Integrate your patient engagement software, dental marketing, websites, and office phones with Legwork innovative solutions.

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PtEverywhere logo

EMR+ software for cash-pay and hybrid rehab clinics

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PtEverywhere’s patient portal gives patients access to appointments, forms, invoices, payments, superbills, secure messages, telehealth visits, and home exercise program

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GVET logo

Veterinary Management System

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GVET is a cloud-based veterinary management system that allows users to access all vet management functionalities from any device.

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vcita logo

Appointment scheduling and reminder solution

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Customize your patient portal with your logo / clinic colors. Let patients log in and schedule consultations, sessions, book and pay, see the history with past interactions - 24/7 from any device.

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Nexus EHR logo

Modern, Certified EHR with Native AI & Rapid Rx

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A secure 24/7 gateway for patient self-service. Empower patients to book appointments, access lab results, and complete intake forms online. Reduce administrative overhead with secure document sharing and direct clinical alerts within a modern interface.

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WellWink logo

Patient Engagement and Care Management System

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WellWink is a cloud base patient relationship management system designed to help medical office engage with their patients health and communicate with them more effectively beyond office visit.

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Enablemypractice logo

Cloud-based EHR solution for medical professionals.

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Enablemypractice is an EHR (electronic health record) solution, which helps small to large healthcare organizations manage patient engagement, online billing, appointment schedules, medicine databases, and more. The platform provides several features such as communication tools, visit management, artificial intelligence (AI), reporting, electronic prescriptions, chronic care management (CCM), custom templates, live chat, mobile application, and bed management.

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DENmaar Guardian logo

DENmaar wants to be a true partner in your practices growth.

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DENmaar is different. Our EHR & Insurance Revenue Cycle system is designed for 6+ MH/SA providers, including medical EMR for Psychiatry and e-prescription, a wide variety of therapy progress notes - including Wiley Planners. We are reimbursed by claims revenue produced. Plus credentialing services.

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Hypnotes logo

All-in-one practice management solution

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Hypnotes is an all in one place platform for streamlining practice management operations. Hypnotherapists, yoga therapists, massage therapists, psychotherapists, and psychologists can benefit from advanced features.

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Collectly logo

Medical billing management platform

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Collectly is a patient interaction platform, designed to optimize the medical billing process in healthcare settings. Features like automated check-ins, multiple payments options, and billing handles patient cash flow.

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BeeHealthy logo

Patient engagement platform with proven business impact.

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BeeHealthy is a awarded* module based, white-label, software as a service (SaaS) platform for digitizing healthcare service provision - with proven business impact from primary and secondary care.

*) 2022 Impact of the Year Award (Finland)

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ClearGage logo

Comprehensive healthcare payments technology solution

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ClearGage cloud-based healthcare financial technology solutions optimize financial performance of small to mid-size healthcare organizations through automated patient billing, configurable payment solutions, online payment portals and integrations with EHR and practice management software vendors.

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