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Top Rated Document Control Software with Change Management

Last updated: May 2026

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96 software options

Document Locator logo

Windows-based document management solution.

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Document control software to comply with regulations and standards that's easy to use because of intelligent integration with Windows.

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MasterControl Quality Excellence logo

Cloud-based quality management system for life sciences.

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MasterControl's document control software handles the most stringent regulations and standards from around the globe. It reduces overall compliance cost and increases efficiency, thus accelerates time to market.

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QT9 QMS logo

Fully Validated QMS for Compliance and Quality Automation

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Eliminate your paper documents and centrally manage documents from anywhere. The QT9 QMS is a cloud-based solution that allows you to easily interconnect documents with other locations, departments and people. Control both a master file and a display file (locked PDF) for any document.

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ComplianceQuest logo

Cloud-based quality management tool for manufacturing firms.

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ComplianceQuest is a cloud-based, enterprise quality and safety management system (QHSE) that helps businesses streamline quality, safety, compliance, content, and collaboration management processes across globally distributed supply chain networks. The system is designed to support organizations in managing complex operations and ensuring adherence to regulatory and safety standards.

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Digital Integrated Management System logo

Quality, compliance, governance, improvement & digitization

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Digital Integrated Management System is an AI-powered IMS that connects QMS, DMS, BPM, and GRC to standardize processes, strengthen compliance, and surface real-time insights. Purpose-built for regulated sectors and certified to ISO 27001 with CSV validation, it ensures full traceability and audit readiness.

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Intellect QMS AI logo

QMS AI SaaS and on-premises solution for quality management.

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Intellect is an AI-powered Quality Management System (QMS) designed for manufacturing, life sciences, and other regulated industries. The SaaS and on-premises platform is designed for quality teams to automate processes, ensure compliance, streamline document control, and lowers operational costs.

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QBD.Net logo

Create, control, and manage documents

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QBD.Net document control software supports creation, approval and versioning of documented information, with role-based access, full audit trails, e-signatures, and automatic change notifications/acknowledgement – keeping you paperless and ISO 9001-compliant.

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CapLinked logo

Caplinked Virtual Data Room Better Platform Better Price

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CapLinked is a web-based Virtual Data Room platform that provides a central platform for businesses and their partners to share business documents and sensitive data during critical business transactions.
https://www.caplinked.com/

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Orcanos logo

Compliance for Design Control, Risk and Quality Management

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21 CFR Part 11 Compliant e-DMS

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Mitratech HotDocs logo

Template-driven, automated document & form assembly software

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HotDocs is a document automation solution that turns frequently used documents or forms into intelligent templates for faster reproduction with greater accuracy

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Trackmedium eQMS logo

Cloud-based Quality Management System (eQMS)

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Trackmedium eQMS is a cloud-based platform designed to help businesses of all sizes automate document control and regulatory compliance processes for various industry standards and global regulations, including ISO 9001, ISO 14001, IATF 16949, and OSHA.

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Harrington Quality Management System (HQMS) logo

QMS with customization and integration. On-premise or hosted

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Highly secure Document Control, Audits, Corrective Action, Calibration, Training, and the HQMS Supplier Portal with personalization, configuration, customization, and integration.

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SOLABS QM10 logo

Learn from experience

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A mobile-friendly, integrated, scalable Enterprise Quality Management Software (EQMS) system designed to learn from your experiences.

With SOLABS organization builds all the required controls and visibility to continuously improve in real time. 

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BPAQuality365 logo

Disruptive Quality Software on Microsoft Teams & Office 365

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Prebuilt workflows ensure documents are provisioned correctly, electronically signed, published, revised, archived and users get trained on documents. BPAQuality365 is a modern app for integrated quality, risk and compliance management to run in your Office 365 tenant, with Teams or SharePoint.

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Sierra QMS logo

Automate Regulatory Compliance and Speed Your Innovations!

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Sierra QMS allows you to publish information from your QMS into templatized documents to share with regulatory bodies. Generate validation artifacts directly from source data in application lifecycle projects. Transition published documents through approval workflows using Sierra QMS.

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DocTract logo

AI policy management and collaboration software

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DocTract is a cloud-based policy management software that streamlines the creation, approval, and tracking of organizational policies. The platform features AI-powered capabilities including natural language search, automated document summaries, policy creation templates, and regulatory compliance verification. It includes automated workflow engines, version control, periodic review systems, and integrations with Microsoft Word, Google Docs, Microsoft Entra ID, Okta, and OpenAI.

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Qualityze Suite logo

Intelligent Quality, Powered by AI

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Qualityze Document Control software helps organizations manage, approve, and distribute controlled documents with full version tracking and audit trails. Automate review cycles, ensure compliance with regulatory standards, and maintain accurate, up-to-date documentation across departments.

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Legito logo

Processes. People. Documents. No code automation platform.

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Controlled Document Flow. End-to-end document lifecycle management with automated routing, approvals, dashboards, collaboration and reusable data.

Rich workflow tools to power efficiency or growth. No-code rapid deployment for fast ROI. Regular new features.

400k+ users globally.

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Boxcore logo

Simple-to-use Construction Safety Software.

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Boxcore is a cloud-based solution for construction businesses of all sizes to capture, share and track on-site safety documents.

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FileHold logo

Simple. Flexible. Document Management that Works!

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FileHold’s document review and workflow software is designed for organizations with 10+ users. Includes version control, automated workflows, mobile access, and Microsoft Office integration, making it easy for your team to adopt. Available on-premise or in the cloud, and fully mobile-ready.

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Avokaado logo

Contract intelligence platform for legal, revenue, and ops.

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Avokaado is an all-in-one contract lifecycle management platform that helps teams manage their documents without ever leaving the platform enabled by: clause-based contract automation, drafting based on smart templates, workflow management with digital signing and electronic storing.

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PowerDMS logo

Cloud-based platform to manage workforce cycle

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PowerDMS is a software designed to streamline operations and enhance compliance across the public safety and healthcare sectors. The solution offers a wide range of specialized features to address the unique needs of these industries. Its policy management capabilities enable organizations to manage, maintain, and prove staff and agency-wide compliance.

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BIS Safety Software logo

Learning and Compliance for high-risk industries.

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BIS Safety Software unites training, compliance, and safety management into one platform. With tools for learning, audits, incidents, assets, drivers, and certifications, BIS is built for high-risk industries to ensure compliance, safety, and workforce readiness.

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Document Compliance Network logo

Cloud-based automation for food safety documentation

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Document Compliance Network automates food safety documentation. It allows organizations to eliminate the need for paperwork and is used to automatically collect, store, track, audit, and share food safety documentation for suppliers and customers.

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Momentum QMS logo

Quality and Safety software with no User License Fees

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Momentum QMS is an solution designed to help manufacturing, mining, & aviation sectors maintain the quality standards of their products/services, & ensure regulatory compliance.

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