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e-Prescribing Software with Credit Card Processing (2026)

Last updated: March 2026

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Key features of e-Prescribing Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • HIPAA Compliant: Reviewers emphasize the importance of secure patient data handling, encryption, and adherence to federal regulations for privacy protection. 97% of reviewers rated this feature as important or highly important.
  • Prescription Renewal: Users find prescription renewals easy and efficient, with helpful alerts and quick reordering processes improving workflow. 95% of reviewers rated this feature as important or highly important.
  • Medication History: Reviewers value seeing comprehensive patient medication records, aiding in accurate prescribing and reducing risks of polypharmacy. 93% of reviewers rated this feature as important or highly important.
  • EPCS Compliant: Users appreciate the secure, compliant handling of controlled substances, with multifactor authentication enhancing safety. 93% of reviewers rated this feature as important or highly important.
  • Charting: Reviewers highlight customizable templates and ease of use, which improve efficiency and meet specific practice needs. 92% of reviewers rated this feature as important or highly important.
  • Medication Alerts/Warnings: Users find medication alerts useful for enhancing patient safety by flagging potential drug interactions and contraindications. 90% of reviewers rated this feature as important or highly important.
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22 software options

PracticeSuite logo

PracticeSuite

Cloud-based Medical Billing & Practice Management platform

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PracticeSuite's e-prescribing platform enables providers to safely and securely transmit prescriptions to over 70,000 pharmacies, without having to navigate away from the patient's encounter in the EMR, meeting regulatory requirements while improving medication adherence.

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CharmHealth logo

CharmHealth

Category Leaders

AI-based healthcare platform for medical practices

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CharmHealth is an AI-based healthcare platform offering electronic health records, practice management, and medical billing solutions for medical practices of all sizes. The system features an AI scribe that automates documentation during patient encounters and integrates with pharmacies, labs, and devices. The platform includes patient engagement tools that allow individuals to schedule appointments, access records, and manage their healthcare information.

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TherapyNotes, LLC logo

Online mental health EMR and practice management software.

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Web-based practice management & electronic health records (EHR) software for behavioral health with thousands of active users, and unlimited customer support.

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Pabau logo
Category Leaders

Practice management system for healthcare

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Pabau is an all-in-one practice management software designed for healthcare businesses. The system offers digital patient records, online booking capabilities, calendar management, and integrated payment processing to streamline administrative workflows. Pabau also includes marketing tools, inventory management, and reporting features that help medical practices operate efficiently while maintaining secure patient data.

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Qualifacts Insync logo
Category Leaders

Cloud-based EHR and practice management software.

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Our EMR integrated e-prescribing is mobile-friendly for ease of access. Features include Eligibility and Formulary Checks, Medication History, EPCS, ePA, RTPB and APPRISS Integration for PMDP Checking. The end result is more accurate, easily-filled prescriptions for you and your practice.

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RXNT logo
Category Leaders

Cloud-based Practice Management, EHR, and eRx Software

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RXNT's cloud-based E-Prescribing solution is EPCS-certified and allows providers to easily, accurately write prescriptions from anywhere. Streamline your practice with a seamless connection to our EHR, and get instant access to medical and prescription history from a single platform.

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DrChrono logo

Cloud healthcare management platform

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DrChrono is a cloud-based healthcare platform that integrates electronic health records, practice management, and medical billing functionalities. The system offers customizable clinical notes, telehealth capabilities, and specialty-specific templates for medical practices of various sizes. DrChrono provides mobile accessibility through iOS apps, allowing healthcare providers to manage patient care from multiple devices.

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DocVilla logo
Category Leaders

Medical Practice Management Software

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DocVilla: transform your independent medical practice with a comprehensive suite of Cloud-Based EMR and EHR software, telemedicine, e-prescribing, lab integration, Fullscript, analytics, POS, Patient portal, and inventory management. Secure, efficient, and hosted on Google Cloud and AWS.

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TriMed Complete logo

EHR, PM, Portal, Mobile, Check In Module, & Telehealth

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TriMed offers a complete software suite that includes: EHR, Practice Management, Patient Portal, Mobile, Digital Check-in and Telemed.

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My Best Practice logo

Software for managing healthcare operations and records

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My Best Practice, the EHR for evidence-based clinicians, simplifies creating and maintaining client accounts, scheduling appointments, managing client information, billing, and more.

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Provet logo

One veterinary workspace. Tailored to how you practice.

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Cloud veterinary software that runs your clinic from booking to invoice in one workspace — with 150+ integrations and built-in AI.

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iCare logo

Focus on patient care, not software.

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iCare is a cloud-based medical scheduling solution, which helps small to large healthcare organizations manage patient care plans, electronic health records, lab results, and more. The platform offers various features such as custom workflows, financial insights, compliance management, third-party integration, and pre-made templates.

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Intelligent Medical Software logo

Intelligent technology that adapts to your practice.

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Intelligent Medical Software is an electronic medical records (EMR) suite of solutions designed to help healthcare businesses. Key features include chronic care management, health maintenance, clinical flow charts, a care portal, claims scrubbing, e-faxing, and clinical decision support.

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Nexus EHR logo

Certified, Modern and affordable healthcare platform.

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Nexus EHR includes ePrescribing with EPCS and PDMP. Easy workflow, maintain doctors medication lists, preferred pharmacy selection for each patient from self-service.Pull surescript medication history for patients.

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ChartLogic EHR logo

Cloud-based EHR solution for hospitals and clinics

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ChartLogic is an integrated electronic health recording (EHR) solution offering benefits of electronic medical recording (EMR), practice management and medical billing services in a combined suite. The solution helps to streamline clinical operations and ensures paperless workflow.

Read more about ChartLogic EHR

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HARMONY Medical logo

Fully integrated HIPPA compliant practice management

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Harmony is a fully integrated HIPPA compliant practice management software with color-coded scheduling, comprehensive insurance and patient billing

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DENmaar Guardian logo
Category Leaders

DENmaar wants to be a true partner in your practices growth.

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DENmaar is different. Our EHR & Insurance Revenue Cycle system is designed for 6+ MH/SA providers, including medical EMR for Psychiatry and e-prescription, a wide variety of therapy progress notes - including Wiley Planners. We are reimbursed by claims revenue produced. Plus credentialing services.

Read more about DENmaar Guardian

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CarePaths EHR logo

E-Health Records & Practice Management System w/ Telehealth

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ONC-Certified & HIPAA compliant cloud-based EHR and practice management platform with telehealth. Accept e-referrals, FREE claim submissions, online payments, E-statements, online scheduling, appointment reminders, clinical documentation, customizable forms, secure messaging, outcomes monitoring.

Read more about CarePaths EHR

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Consentz logo

Clinic management system for building patient relationships

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Consentz is a clinic management software with a range of features designed to enhance the patient experience, improve revenue, and mitigate risks for businesses. With Consentz, users can educate patients about their treatments, ensuring they have all the necessary information.

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MicroMD logo

Cloud or on-site Practice Management, EHR, and eRx Software

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Henry Schein MicroMD provides simple, customizable practice management and 2015 ONC Certified Electronic Medical Records & e-Prescribing software.

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Enablemypractice logo

Cloud-based EHR solution for medical professionals.

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Enablemypractice is an EHR (electronic health record) solution, which helps small to large healthcare organizations manage patient engagement, online billing, appointment schedules, medicine databases, and more. The platform provides several features such as communication tools, visit management, artificial intelligence (AI), reporting, electronic prescriptions, chronic care management (CCM), custom templates, live chat, mobile application, and bed management.

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Meddbase logo

Improving business efficiency, security, and patient care.

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A fully-secure and scalable healthcare management solution empowering businesses to improve efficiency, security and patient care. Covering; booking, clinical, billing, communications, analytics and support modules, Meddbase is securely accessed from any web-enabled device, anywhere any time.

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