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Top Rated HIPAA Compliance Software with Microsoft 365

Last updated: June 2026

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17 software options

Caspio logo

Low-code application development platform.

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Caspio is a low-code application development platform for building custom, data-driven business applications without coding. It combines a cloud database, visual app builder, workflow automation, and enterprise-grade compliance. Unlimited users with no per-user pricing on every plan.

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Onspring logo

Cloud-based GRC solution for enterprises and governments.

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Onspring is a cloud-based platform that helps businesses automate governance, risk, and compliance (GRC) management on a centralized interface. The platform offers a suite of ready-made products that work together seamlessly, allowing organizations to efficiently manage various GRC aspects including risk, compliance, third-party risk, audit, regulatory change, policy, and business continuity. It allows users to manage incident response, streamline problem management, and build workflows.

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Secureframe logo

Automate SOC 2, ISO 27001, HIPAA and PCI DSS compliance

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Secureframe helps hundreds of companies stay HIPAA compliant through automation and continuous monitoring. Secureframe enables companies to get compliant within weeks and monitors 100+ services, including AWS, GCP, and Azure, to ensure they stay compliant.

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Safetica logo

Intelligent Data Security

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Safetica Intelligent Data Security protects sensitive enterprise data wherever your team uses it.
With advanced data discovery, context-aware classification, proactive threat prevention and adaptive security, Safetica provides comprehensive visibility and control over your data.

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PowerDMS logo

Cloud-based platform to manage workforce cycle

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PowerDMS is a software designed to streamline operations and enhance compliance across the public safety and healthcare sectors. The solution offers a wide range of specialized features to address the unique needs of these industries. Its policy management capabilities enable organizations to manage, maintain, and prove staff and agency-wide compliance.

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LogicGate Risk Cloud logo

Cloud-based compliance solution for GRC.

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LogicGate Risk Cloud is a no-code governance, risk, and compliance (GRC) platform that scales and adapts to your changing business needs and regulatory requirements. It combines a suite of purpose-built applications with intuitive technology that allows risk professionals to form, evolve, and communicate a market-leading risk strategy.

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Digital Integrated Management System logo

Quality, compliance, governance, improvement & digitization

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Interfacing’s Enterprise Process Center (EPC) provides a process-driven approach to implement, manage and maintain HIPAA initiatives.

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Jatheon logo

Data archiving software

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Jatheon Cloud is an AI-powered data archiving and governance platform built on AWS. It securely captures, stores, searches, and produces communications like email, social, calls, texts, chats, and AI conversations, automating compliance, retention, FOIA, and ediscovery with embedded AI.

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JupiterOne logo

Security & Compliance. At the Speed of DevOps.

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Maintain complete visibility across your digital environments leveraging the graph-based, API-powered and data-driven JupiterOne. Simplify compliance evidence collection, shorten the time between findings and remediation and manage configuration of your critical resources.

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Drata logo

Cloud-based compliance and audit management software

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Designed for businesses of all sizes, Drata is a cloud-based compliance management software that allows users to monitor risk assessments, create treatment plans, and streamline auditing processes.

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LogicManager logo

Cloud-based risk management tool for organizations.

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LogicManager's enterprise risk management software centralizes risk management, governance, and compliance. Its AI-powered risk ripple analytics uncovers hidden risk connections, while tools like completeness checker ensure audit-ready assurance. Organizations can systematically identify, assess, mitigate, monitor, and report risks via an intuitive interface with interactive dashboards.

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ArcTitan Email Archiving logo

Secure Email Archiving. Compliant, Fast, Secure & Office365

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An email archiving product allowing users to securely archive your business emails and simply retrieve these emails. ArcTitan is compliant, very fast, secure and office365 friendly.

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TimeTap logo

HIPAA-compliant scheduling for complex booking needs

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TimeTap is a HIPAA- and GDPR-compliant appointment scheduling platform built for organizations with complex booking requirements. It automates scheduling, reminders, and availability while securely capturing client information across staff, locations, and time zones.

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Contentverse logo

Simple, secure document management for everyone

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Contentverse is a secure, versatile, fully-featured enterprise content management solution. 128-bit encryption. DocuSign integration. On-premise and/or cloud implementation. With a robust indexing module that can detect text, barcodes, and QR codes on scanned pages as searchable metadata.

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Vanta logo

Cloud-based audit solution for compliance.

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Vanta helps 9,000+ teams start and scale their security programs, like Atlassian, Quora to Chili Piper and incident.io. Automate 35+ compliance frameworks, centralize GRC, accelerate security reviews, and build trust.

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TriNet HR Plus logo

HR | Onboarding | Payroll | Benefits | Compliance

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Leverage a trusted solution to ensure you’re always within compliance across HR, payroll and benefits regulations.

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M365 Manager Plus logo
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Management, reporting, auditing, and monitoring of Microsoft

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M365 Manager Plus is a reporting, auditing, monitoring, management, and security solution for Microsoft 365. Designed for businesses of all sizes, it helps users manage Exchange Online, Azure AD, Microsoft Teams, OneDrive for Business, and other services from a centralized dashboard.

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