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Top Rated HIPAA Compliance Software with Microsoft 365

Last updated: September 2026

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20 software options

Onspring logo

Cloud-based GRC solution for enterprises and governments.

Onspring is a cloud-based platform that helps businesses automate governance, risk, and compliance (GRC) management on a centralized interface. The platform offers a suite of ready-made products that work together seamlessly, allowing organizations to efficiently manage various GRC aspects including risk, compliance, third-party risk, audit, regulatory change, policy, and business continuity. It allows users to manage incident response, streamline problem management, and build workflows.

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Secureframe logo

Automate SOC 2, ISO 27001, HIPAA and PCI DSS compliance

Secureframe helps hundreds of companies stay HIPAA compliant through automation and continuous monitoring. Secureframe enables companies to get compliant within weeks and monitors 100+ services, including AWS, GCP, and Azure, to ensure they stay compliant.

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Safetica logo

Intelligent Data Security

Safetica Intelligent Data Security protects sensitive enterprise data wherever your team uses it.
With advanced data discovery, context-aware classification, proactive threat prevention and adaptive security, Safetica provides comprehensive visibility and control over your data.

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PowerDMS logo

Cloud-based platform to manage workforce cycle

PowerDMS is a software designed to streamline operations and enhance compliance across the public safety and healthcare sectors. The solution offers a wide range of specialized features to address the unique needs of these industries. Its policy management capabilities enable organizations to manage, maintain, and prove staff and agency-wide compliance.

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LogicGate logo

Cloud GRC platform for enterprise risk & compliance

Cloud-based enterprise GRC platform centralizing cyber risk, TPRM, controls compliance, ERM, and AI governance for mid-to-large.

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Digital Integrated Management System logo

Quality, compliance, governance, improvement & digitization

Interfacing’s Enterprise Process Center (EPC) provides a process-driven approach to implement, manage and maintain HIPAA initiatives.

Read more about Digital Integrated Management System

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Jatheon logo

Data archiving software

Jatheon Cloud is an AI-powered data archiving and governance platform built on AWS. It securely captures, stores, searches, and produces communications like email, social, calls, texts, chats, and AI conversations, automating compliance, retention, FOIA, and ediscovery with embedded AI.

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JupiterOne logo

Security & Compliance. At the Speed of DevOps.

Maintain complete visibility across your digital environments leveraging the graph-based, API-powered and data-driven JupiterOne. Simplify compliance evidence collection, shorten the time between findings and remediation and manage configuration of your critical resources.

Read more about JupiterOne

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LogicManager logo

Cloud-based risk management tool for organizations.

LogicManager's enterprise risk management software centralizes risk management, governance, and compliance. Its AI-powered risk ripple analytics uncovers hidden risk connections, while tools like completeness checker ensure audit-ready assurance. Organizations can systematically identify, assess, mitigate, monitor, and report risks via an intuitive interface with interactive dashboards.

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ArcTitan Email Archiving logo

Secure Email Archiving. Compliant, Fast, Secure & Office365

An email archiving product allowing users to securely archive your business emails and simply retrieve these emails. ArcTitan is compliant, very fast, secure and office365 friendly.

Read more about ArcTitan Email Archiving

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Caspio logo

AI platform for building custom business applications.

Caspio is an AI platform for building custom business applications: the databases, portals, dashboards, and workflow tools organizations rely on to run operations.

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TimeTap logo

HIPAA-compliant scheduling for complex booking needs

TimeTap is a HIPAA- and GDPR-compliant appointment scheduling platform built for organizations with complex booking requirements. It automates scheduling, reminders, and availability while securely capturing client information across staff, locations, and time zones.

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Contentverse logo

Simple, secure document management for everyone

Contentverse is a secure, versatile, fully-featured enterprise content management solution. 128-bit encryption. DocuSign integration. On-premise and/or cloud implementation. With a robust indexing module that can detect text, barcodes, and QR codes on scanned pages as searchable metadata.

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Vanta logo

Cloud-based audit solution for compliance.

Vanta helps 9,000+ teams start and scale their security programs, like Atlassian, Quora to Chili Piper and incident.io. Automate 35+ compliance frameworks, centralize GRC, accelerate security reviews, and build trust.

Read more about Vanta

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TriNet HR Plus logo

HR | Onboarding | Payroll | Benefits | Compliance

Leverage a trusted solution to ensure you’re always within compliance across HR, payroll and benefits regulations.

Read more about TriNet HR Plus

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Zivver logo

Email Security Made Effortless

Zivver is email security software which helps enterprises transfer business documents and ensure secure e-mail communication. It allows users to retract emails, view risks, causes, and impact of data breaches, configure workflows, and generate custom reports.

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Upvio logo

Remote vitals in 30 seconds from a camera.


Vitals AI turns a 30-second camera face scan into 20+ vital and risk markers, with template-based scans, secure link sharing, and enterprise-ready deployment.

Read more about Upvio

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StoriiCare logo

Software for adult day care and assisted living providers

StoriiCare helps nursing homes, adult day care centers, and assisted living providers manage patient admissions, staff scheduling, communication, reporting, and more. Users can create custom care plans, track progress, and upload documents in a centralized repository for future reference.

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M365 Manager Plus logo
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Management, reporting, auditing, and monitoring of Microsoft

M365 Manager Plus is a reporting, auditing, monitoring, management, and security solution for Microsoft 365. Designed for businesses of all sizes, it helps users manage Exchange Online, Azure AD, Microsoft Teams, OneDrive for Business, and other services from a centralized dashboard.

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Avochato logo

SMS texting and live chat for sales, support & ops teams

Avochato is an SMS/text messaging and live chat solution for marketing, sales & support teams, which allows users to send, receive, and collaborate on messages from customers

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