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Top Rated Quality Management Software with Electronic signature capture

Last updated: July 2026

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164 software options

Dot Compliance logo

Cloud-based quality management tool for life science firms.

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Dot Compliance provides a truly off-the-shelf quality management solution for record-fast deployments that scale with your business. Benefit from pre-configured modules, complete with a validation package, natively built on the Salesforce platform.

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HSI Donesafe logo

Cloud-based EHS management tool for workplace safety.

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Ensure quality at every step with centralized processes. Log non-conformances, track corrective actions, and monitor trends to drive improvements and maintain high standards.

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Qualio logo

Cloud-based quality management tool for life science firms.

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Achieve 100% FDA/ISO/GxP compliance. 5x faster Document Control, Training, CAPA, NCRs, Audits and more. 2x faster accreditation.

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Propel logo

Unified PLM, QMS, and PIM for modern product companies.

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Maintain product compliance globally and integrate quality with design to improve products before they reach the market. Take corrective actions more efficiently after launch. Our cloud-native QMS helps track and quickly resolve product issues, non-conformances and customer complaints.

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Qualityze Suite logo

Intelligent Quality, Powered by AI

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Qualityze Quality Management software helps organizations standardize quality processes, improve compliance, and drive continuous improvement. Centralize nonconformance, CAPA, audits, document control, and risk management in one unified, AI-powered platform.

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MasterControl Quality Excellence logo

Cloud-based quality management system for life sciences.

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The MasterControl Quality Management System (QMS), called "MasterControl Quality Excellence", enables companies to eliminate their paper-based quality processes, while increasing their efficiency in compliance.

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Sierra QMS logo

Automate Regulatory Compliance and Speed Your Innovations!

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Sierra QMS makes it easy for your team to design, plan, and track your quality roadmap's progress and regulatory goals! Strategically map out your quality journey by utilizing Sierra QMS, ensuring you reach each of your compliance milestones in your desired timeframes.

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SBS Quality Database logo

The Best Value in Quality Management Software

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The SBS Quality Management Software suite consists of 5 modules that dramatically improve the efficiency and efficacy of your QMS. The SBS QMS Suite manages document lifecycle, employee training, CAPA, Nonconformances, audits, risk management, calibration, preventive maintenance, inspection & SPC.

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QT9 QMS logo

Fully Validated QMS for Compliance and Quality Automation

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The most adaptable & easy to use quality management software. The QT9 QMS is a highly modular web-based system designed for biomedical, pharmaceutical, medical device, aerospace and general manufacturing companies. Automate ISO 9001, ISO 13485 with FDA 21 CFR Part 11 electronic signature compliance.

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Digital Integrated Management System logo

Quality, compliance, governance, improvement & digitization

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Interfacing’s EPC ensures full visibility from audit management, CAPA, regulatory training and management of standard operating procedu

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CAQ.Net logo

Quality Management Software Solutions

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CAQ.Net quality management software supports building, maintaining and improving your QM system with modular process, document, risk, audit and action management plus AI assistants – fully traceable PDCA workflows for staying audit-ready.

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VLX logo

Digital Inspection, Audit and Verification Software

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Visualogyx is a cloud-based platform that streamlines quality assurance inspections and audits. With an intuitive design, users can use built-in or custom forms to streamline the entire quality management process with centralized data storage, real-time monitoring, and instant reporting.

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Web QMS logo

All-in-one software to maintain ISO or API certifications.

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Web QMS is a cloud-based, management systems software that helps you achieve, maintain and improve your ISO or API certifications. Give your employees full access and visibility to your quality, environmental, occupational health & safety or information security management system- anytime, anywhere!

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Grand Avenue Software logo

Purpose-built eQMS for medical device and life science teams

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Grand Avenue Software provides a modular electronic Quality Management System (eQMS) specifically designed for medical device companies. The cloud-based solution supports compliance with industry standards including ISO 13485, ISO 9001, FDA regulations, and EU MDR while automating key quality processes for improved audit readiness. Organizations can start with essential modules and expand functionality as their compliance needs evolve.

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Redzone logo

Redzone: Connected manufacturing for better execution.

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Redzone's digital QMS embeds line-side quality checks, audits, and corrective actions directly into operator workflows. Connected production data creates meaningful context automatically. It replaces paper, eliminates lag, and keeps teams permanently audit-ready — with 75% less admin burden.

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1factory logo

Quality and manufacturing operations platform

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1factory is a quality and manufacturing operations platform that provides solutions for product quality, supplier quality, and compliance management. The software includes features such as automated PDF ballooning, first article inspection, PPAP and APQP documentation, CMM data import, statistical process control, gage calibration, and nonconformance management. The platform offers document control, training management, supplier qualification, and incoming quality control capabilities.

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WorkClout logo

# 1 Rated Quality Platform for the Automotive Industry

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WorkClout centralizes digital inspections, corrective actions, safety & quality procedures, knowledge building, and data reporting. Get your quality back on track with the best quality tool that money can buy.

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flowdit logo

Streamlining Quality, Empowering Compliance

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flowdit’s quality management solution ensures high standards by streamlining inspections, audits, and compliance tracking. With real-time updates and powerful analytics, businesses can maintain product quality and improve operational performance.

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Checklist Fácil logo

Checklist Fácil is software for audits and inspections

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Checklist Fácil is a solution focused on operational efficiency and simplifies the execution of auditing and inspection process checklists. Users can create intelligent checklists with the option to add dependent questions, images, barcodes, and more. Available in English, Spanish, and Portuguese.

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Process Street logo

AI-enabled compliance operations platform.

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Process Street is an AI-powered compliance operations platform that turns policies into automated workflows, enabling teams to manage controlled documents, run no-code processes, and stay audit-ready.

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GoAudits logo

Audit and inspection management software

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GoAudits is a mobile inspection and auditing platform that enables businesses to conduct digital inspections across multiple industries. The application offers customizable checklists, offline functionality, and automated report generation to streamline quality control processes. GoAudits works across web, iOS, and Android devices, allowing teams to capture data, assign follow-up actions, and analyze performance trends through interactive dashboards.

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ShopXpert logo

A simple and powerful ERP Software for your Business

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A simple and powerful ERP Software for your Business, Job Shop, Fabrication, Service Shop and more.

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AssetPool logo

Assets and inspection management software

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AssetPool's smart inspection solution is highly customisable to suit your unique processes. AssetPool requires a once-off input of the asset types and checklists, which are specific to your business. Create the client, create the site, onboard your assets and let AssetPool do the rest.

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Qualcy QMS logo

QMS for complex engineering, bio-medical devices & pharma

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Qualcy QMS is a quality management system which enables complex engineering, bio-medical device and pharma companies to manage their records, assets and documents with ISO and FDA compliance, audit trails, role-based identification, automated reminders, e-signature functionality, and more.

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KAWAK logo

Business management and document control solution

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kawak is a business management and document control solution that helps businesses manage audits, equipment, risks, human talent, and more from a centralized platform. It allows staff members to utilize the built-in customer service module to set up PQRS

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