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Top Rated Medical Billing Software with Mid size business

Last updated: October 2026

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158 software options

Dentrix Ascend logo

Cloud-native dental software built to drive growth

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Cloud-based dental practice management software that combines AI-powered clinical tools, patient engagement, revenue cycle management,

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Euclid logo

Medical practice management system to process claims.

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Welcome to our cutting-edge medical billing processing platform, where we have redefined the way healthcare organizations handle their billing procedures. We have meticulously designed our platform to streamline the entire medical billing process, eliminating bottlenecks and saving you time.

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RCx logo

Aptarro helps revenue cycle teams make right easy.

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Cut manual claim edits by 82%+, free staff to focus on revenue—not rework, and see results in your first billing cycle. We help you make right easy.

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AdvancedMD Billing Services logo

Cloud based medical billing and claim processing software

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AdvancedBilling from AdvancedMD is a cloud based medical billing software that helps in automating and enhancing tasks related to revenue capturing

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Waystar logo

Simplify healthcare payments

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Waystar delivers an AI-powered, end-to-end platform that simplifies healthcare payments and advances the autonomous revenue cycle. Built for organizations of all sizes, Waystar supports 1M+ providers to help reduce complexity, prevent revenue leakage, and accelerate reimbursement.

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OpenPM logo

Medical Billing software for the healthcare sector

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OpenPM is designed to optimize and modernize the revenue cycle. Through the automation and streamlining of workflow processes, organizations reduce staff time and the overall cost of collections, while maximizing revenues.

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SimplePractice logo

Appointment scheduling and reminder solution

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SimplePractice is an all-in-one practice management solution that helps businesses simplify administrative tasks, such as scheduling, billing, and documentation, allowing health and wellness professionals to focus on providing excellent client care. The platform offers a robust set of features designed to help practitioners thrive.

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EHRYourWay logo

Streamlined care for mental health professionals.

EHR YOUR WAY is a fully integrated behavioral health and clinical care EHR software. It is configurable for mental health and clinical health specific needs and is an ONC certified cloud-based EHR. EHR YOUR WAY is trusted by mental health professionals nationwide and is suitable for behavioral health agencies with 15 or more users.

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Jane logo

Practice management software designed by real clinic owners.

Jane is a cloud-based practice management software designed to help health and wellness practitioners manage online booking, scheduling, billing, and more.

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Pabau logo

Practice management system for healthcare

Pabau is an all-in-one practice management software designed for healthcare businesses. The system offers digital patient records, online booking capabilities, calendar management, and integrated payment processing to streamline administrative workflows. Pabau also includes marketing tools, inventory management, and reporting features that help medical practices operate efficiently while maintaining secure patient data.

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IntakeQ logo

Web-based intake forms management software

IntakeQ is an online intake form solution that enables healthcare professionals to securely exchange electronic forms with their patients prior to appointments

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TriMed EHR logo

Integrated EHR, practice management and AI tools

TriMed is a customizable, cloud-based EHR and practice management platform for independent medical practices. It combines clinical, financial and patient engagement workflows with AI tools, mobile access, digital check-in, telemedicine and direct support from the team that develops the software.

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ClinicMind logo

Healthcare practice management platform

ClinicMind offers a healthcare practice management platform integrating electronic health records, revenue cycle management, and patient engagement tools. It provides solutions for specialties like chiropractic and mental health, featuring AI-powered documentation, telehealth, and virtual front desk services. ClinicMind enhances workflows and patient experience through interconnected modules.

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SPRY logo

AI-Native EMR, Billing & RCM Built for Outpatient Rehab

Cloud-based EMR and practice management platform for outpatient PT, OT, SLP, and chiropractic clinics, with AI-assisted documentation.

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ECP logo

All-in-one platform purpose-built for assisted living.

ECP is the all-in-one platform purpose-built for assisted living communities. It connects eMAR, EHR, CRM, Move-Ins, Billing, and Insights in one system built on a single resident record. Trusted by 8,500+ communities across all 50 states. 100% US-based support.

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Advanced Data Systems logo

AI-enabled healthcare software for medical practices

Advanced Data Systems provides comprehensive healthcare software solutions including Practice Management, Electronic Health Records, and Radiology Information Systems. The ONC-certified platform features AI-driven tools like MedicsScribeAI for voice-to-text documentation and integrates scheduling, billing, and clinical documentation functionalities. The system serves multiple medical specialties with customizable workflows designed to enhance operational efficiency.

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Practice Mate logo

Practice management software for healthcare organizations

Practice Mate by Office Ally is a HIPAA-compliant practice management solution that simplifies revenue cycle management, reporting, billing, and streamlined booking to increase efficiency in your practice. Get started today at no cost.

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ModMed logo

Cloud-based EHR & practice platform for specialists

ModMed® BOOST RCM combines certified specialty coders with AI-driven insights to help streamline billing, reduce denials and accelerate reimbursements. Integrated with EMA®, BOOST keeps revenue cycles healthy while freeing staff to focus on patient care

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StoriiCare logo

Software for adult day care and assisted living providers

StoriiCare helps nursing homes, adult day care centers, and assisted living providers manage patient admissions, staff scheduling, communication, reporting, and more. Users can create custom care plans, track progress, and upload documents in a centralized repository for future reference.

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Anagram logo

Vision insurance benefit management for eyecare providers

Anagram, formerly Patch, allows eye care providers to navigate all vision plans in a single software tool delivering eligibility, benefits, and claims for vision plans so that you can focus on patient care instead of vision insurance administration.

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Prompt Health logo

Cloud-based EMR for outpatient rehab therapy

Cloud-based, AI-powered EMR and practice management platform for U.S.

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MDnet EHR logo

Enabling Excellence: Empowering Doctors with Technology.

Unlocking Seamless Medical Billing: Experience the efficiency of our AI-powered system that automates front office tasks, streamlines admin processes, and accelerates reimbursements with automated claims

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TynetOnline logo

Electronic health record (EHR) and medical billing solution

Solutions to expedite Medicare / insurance claims reimbursement

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iCare logo

Focus on patient care, not software.

iCare is a cloud-based medical scheduling solution, which helps small to large healthcare organizations manage patient care plans, electronic health records, lab results, and more. The platform offers various features such as custom workflows, financial insights, compliance management, third-party integration, and pre-made templates.

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Luma Health logo

Patient engagement and medical billing solution

Luma Health offers a patient success platform designed to help businesses unify and automate patient journeys for healthcare organizations. The platform provides a comprehensive suite of tools to streamline patient access, retention, referrals, scheduling, waitlist management, and feedback. It can be integrated with all major electronic health record (EHR) systems, enabling bidirectional data exchange and a seamless patient experience.

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