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Document Control Software with ISO Standards Management (2026)

Last updated: March 2026

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Key features of Document Control Software

Based on GetApp's analysis of verified user reviews collected between July 2021 and August 2024.

  • Electronic Signature: Reviewers emphasize security, compliance, workflow efficiency, and audit traceability, highlighting ease of remote signing and integration with signature platforms. 91% of reviewers rated this feature as important or highly important.
  • Document Management: Users value centralized storage, version control, easy retrieval, and streamlined workflows, enhancing compliance and collaboration across the organization. 87% of reviewers rated this feature as important or highly important.
  • Access Controls/Permissions: Reviewers appreciate precise control over document access, enhanced security, compliance, and the ability to manage user roles and permissions effectively. 85% of reviewers rated this feature as important or highly important.
  • Quality Control: Users highlight standardized templates, timely updates, and integrated QC processes ensuring compliance and continuous improvement in quality management. 84% of reviewers rated this feature as important or highly important.
  • Version Control: Reviewers value tracking and comparing document versions, maintaining audit trails, and ensuring the use of the most current versions for compliance and accuracy. 80% of reviewers rated this feature as important or highly important.
  • Corrective and Preventive Actions (CAPA): Users highlight automated workflows, integration with other modules, compliance tracking, and the ability to efficiently manage and resolve quality issues. 74% of reviewers rated this feature as important or highly important.
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53 software options

Document Locator logo

Windows-based document management solution.

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Document control software to comply with regulations and standards that's easy to use because of intelligent integration with Windows.

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Fully Validated QMS for Compliance and Quality Automation

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Eliminate your paper documents and centrally manage documents from anywhere. The QT9 QMS is a cloud-based solution that allows you to easily interconnect documents with other locations, departments and people. Control both a master file and a display file (locked PDF) for any document.

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Cloud-based quality management system for life sciences.

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MasterControl's document control software handles the most stringent regulations and standards from around the globe. It reduces overall compliance cost and increases efficiency, thus accelerates time to market.

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Business management and document control solution

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kawak is a business management and document control solution that helps businesses manage audits, equipment, risks, human talent, and more from a centralized platform. It allows staff members to utilize the built-in customer service module to set up PQRS

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Quality, compliance, safety and risk management

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Ideagen Quality Management is a quality, safety and risk management system offering tools for audit management, document control incident management, corrective actions and more

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Software to automate quality management processes.

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Qualio logo

Cloud-based quality management tool for life science firms.

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Document control software for compliant document management.

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ComplianceQuest logo

Cloud-based quality management tool for manufacturing firms.

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ComplianceQuest is a cloud-based, enterprise quality and safety management system (QHSE) that helps businesses streamline quality, safety, compliance, content, and collaboration management processes across globally distributed supply chain networks. The system is designed to support organizations in managing complex operations and ensuring adherence to regulatory and safety standards.

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Qualityze Suite logo

Intelligent Quality, Powered by AI

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Qualityze Document Control software helps organizations manage, approve, and distribute controlled documents with full version tracking and audit trails. Automate review cycles, ensure compliance with regulatory standards, and maintain accurate, up-to-date documentation across departments.

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QMS AI SaaS and on-premises solution for quality management.

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Intellect is an AI-powered Quality Management System (QMS) designed for manufacturing, life sciences, and other regulated industries. The SaaS and on-premises platform is designed for quality teams to automate processes, ensure compliance, streamline document control, and lowers operational costs.

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Arena QMS logo

Cloud-based quality and compliance management software

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Dot Compliance logo

Cloud-based quality management tool for life science firms.

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Dot Compliance streamlines document and content management across their entire lifecycle, offering version control, lifecycle management, annotations, revisions, and electronic signatures. Office365 integration simplifies collaboration and editing and more.

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ISO 9001 Quality Management System Software

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Collaborative & user friendly approach to implement & maintain ISO 9001 compliance through a complete ISO 9001 software

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eQMS integrates data to reduce risk and ensure compliance.

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Identify, control, track all documented processes and procedures in a centralized and secure location with document control software. Octave Reliance® (formerly ETQ Reliance) is a comprehensive, flexible and proven QMS software for large manufacturing organizations in dozens of industries.

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Document Management System

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Loyal DMS is a solution that can help with the management of documents & contents.

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Momentum QMS is an solution designed to help manufacturing, mining, & aviation sectors maintain the quality standards of their products/services, & ensure regulatory compliance.

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Cloud-based quality management software for life sciences.

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Expert-driven, fully validated eQMS for Life Science companies to streamline quality processes, ensure compliance, and stay audit-ready.

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Enterprise Quality Management System

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Adaptive Compliance Engine (ACE) is a cloud-based quality management system designed to help businesses in biotechnology, cosmetics, pharmaceuticals, healthcare, manufacturing, and other industries manage compliance, quality, and efficiency across all operations in real-time.

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Cloud-based QMS and workflow management software

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Singlepoint is a cloud-based QMS and workflow management software that helps businesses automate and streamline internal audit programs, handle official documents, and track projects across teams. The tool allows users to capture, triage, resolve and analyze multiple workplace incidents.

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21 CFR Part 11 Compliant e-DMS

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Quality, compliance, governance, improvement & digitization

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Digital Integrated Management System is an AI-powered IMS that connects QMS, DMS, BPM, and GRC to standardize processes, strengthen compliance, and surface real-time insights. Purpose-built for regulated sectors and certified to ISO 27001 with CSV validation, it ensures full traceability and audit readiness.

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QISS QMS is software for quality management systems. It is designed to streamline your organization’s processes and support compliance.

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AppQual is a web quality and QHSE management software.

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AppQual is a web quality and QHSE management software. It allows you to manage all your audits, action plans, non-conformities, claims

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Automate Regulatory Compliance and Speed Your Innovations!

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Sierra QMS allows you to publish information from your QMS into templatized documents to share with regulatory bodies. Generate validation artifacts directly from source data in application lifecycle projects. Transition published documents through approval workflows using Sierra QMS.

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Quality and compliance management solution for businesses

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ZenQMS is a cloud-based solution that assists businesses with quality management, employee training, and regulatory compliance. Key features include document management, change control, issue tracking, auditing, data export, notifications, and reporting.

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